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Results for Disease Models, Animal

Publications & Outputs

  1. Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models

    Lobo, D. S. S., Aleksandrova, L., Knight, J., Casey, D. M., el-Guebaly, N., Nobrega, J. N. & Kennedy, J. L., 08/2015, In : Molecular Psychiatry. 20, 8, p. 1002-1010 9 p.

    Research output: Contribution to journalJournal article

  2. Integrin αvβ8-mediated TGF-β activation by effector regulatory T sells is essential for suppression of T-Cell-mediated inflammation

    Worthington, J. J., Kelly, A., Smedley, C., Bauché, D., Campbell, S., Marie, J. C. & Travis, M. A., 19/05/2015, In : Immunity. 42, 5, p. 903-915 13 p.

    Research output: Contribution to journalJournal article

  3. Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease

    McClean, P. L. & Holscher, C., 11/2014, In : Neuropharmacology. 86, p. 241-258 18 p.

    Research output: Contribution to journalJournal article

  4. Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

    Muñoz-Lobato, F., Rodríguez-Palero, M. J., Naranjo-Galindo, F. J., Shephard, F., Gaffney, C. J., Szewczyk, N. J., Hamamichi, S., Caldwell, K. A., Caldwell, G. A., Link, C. D. & Miranda-Vizuete, A., 10/01/2014, In : Antioxidants and Redox Signaling. 20, 2, p. 217-235 19 p.

    Research output: Contribution to journalJournal article

  5. Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia

    Douvaras, P., Mort, R. L., Edwards, D., Ramaesh, K., Dhillon, B., Morley, S. D., Hill, R. E. & West, J. D., 13/08/2013, In : PLoS ONE. 8, 8, 18 p., e71117.

    Research output: Contribution to journalJournal article

  6. A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy

    Jadeja, S., Mort, R. L., Keighren, M., Hart, A. W., Joynson, R., Wells, S., Potter, P. K. & Jackson, I. J., 1/05/2013, In : Investigative Ophthalmology and Visual Science. 54, 5, p. 3569-3578 10 p.

    Research output: Contribution to journalJournal article

  7. The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease

    Long-Smith, C. M., Manning, S., McClean, P. L., Coakley, M. F., O'Halloran, D. J., Holscher, C. & O'Neill, C., 03/2013, In : NeuroMolecular Medicine. 15, 1, p. 102-114 13 p.

    Research output: Contribution to journalJournal article

  8. The incretin analogue D-Ala2GIP reduces plaque load, astrogliosis and oxidative stress in an APP/PS1 mouse model of Alzheimer's disease

    Duffy, A. M. & Hölscher, C., 3/01/2013, In : Neuroscience. 228, p. 294-300 7 p.

    Research output: Contribution to journalJournal article

  9. The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease

    Hamilton, A. & Holscher, C., 17/04/2012, In : Brain Research. 1449, p. 83-93 11 p.

    Research output: Contribution to journalJournal article

  10. Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain

    Hamilton, A., Patterson, S., Porter, D., Gault, V. A. & Hölscher, C., 04/2011, In : Journal of Neuroscience Research. 89, 4, p. 481-489 9 p.

    Research output: Contribution to journalJournal article

  11. Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans

    Benedetto, A., Au, C., Avila, D. S., Milatovic, D. & Aschner, M., 26/08/2010, In : PLoS Genetics. 6, 8

    Research output: Contribution to journalJournal article

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