Home > Research > Browse

Results for Mendelian Randomization Analysis

Publications & Outputs

  1. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

    Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., Cavadino, A., Drogan, D., Padmanabhan, S., Li, S., Yesupriya, A., Leusink, M., Sundstrom, J., Hubacek, J. A., Pikhart, H., Swerdlow, D. I. & 31 others, Panayiotou, A. G., Borinskaya, S. A., Finan, C., Shah, S., Kuchenbaecker, K. B., Shah, T., Engmann, J., Folkersen, L., Eriksson, P., Ricceri, F., Melander, O., Sacerdote, C., Gamble, D. M., Rayaprolu, S., Ross, O. A., McLachlan, S., Vikhireva, O., Sluijs, I., Scott, R. A., Adamkova, V., Flicker, L., Bockxmeer, F. M. V., Power, C., Marques-Vidal, P., Meade, T., Marmot, M. G., Ferro, J. M., Paulos-Pinheiro, S., Humphries, S. E., Palmer, T. M. & InterAct Consortium, 10/07/2014, In : BMJ. 349, 16 p., g4164.

    Research output: Contribution to journalJournal article

  2. Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis

    Holmes, M. V., Lange, L. A., Palmer, T., Lanktree, M. B., North, K. E., Almoguera, B., Buxbaum, S., Chandrupatla, H. R., Elbers, C. C., Guo, Y., Hoogeveen, R. C., Li, J., Li, Y. R., Swerdlow, D. I., Cushman, M., Price, T. S., Curtis, S. P., Fornage, M., Hakonarson, H., Patel, S. R. & 14 others, Redline, S., Siscovick, D. S., Tsai, M. Y., Wilson, J. G., van der Schouw, Y. T., FitzGerald, G. A., Hingorani, A. D., Casas, J. P., de Bakker, P. I. W., Rich, S. S., Schadt, E. E., Asselbergs, F. W., Reiner, A. P. & Keating, B. J., 6/02/2014, In : American Journal of Human Genetics. 94, 2, p. 198-208 11 p.

    Research output: Contribution to journalJournal article

  3. Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

    Holmes, M. V., Simon, T., Exeter, H. J., Folkersen, L., Asselbergs, F. W., Guardiola, M., Cooper, J. A., Palmen, J., Hubacek, J. A., Carruthers, K. F., Horne, B. D., Brunisholz, K. D., Mega, J. L., van Iperen, E. P. A., Li, M., Leusink, M., Trompet, S., Verschuren, J. J. W., Hovingh, G. K., Dehghan, A. & 93 others, Nelson, C. P., Kotti, S., Danchin, N., Scholz, M., Haase, C. L., Rothenbacher, D., Swerdlow, D. I., Kuchenbaecker, K. B., Staines-Urias, E., Goel, A., van 't Hooft, F., Gertow, K., de Faire, U., Panayiotou, A. G., Tremoli, E., Baldassarre, D., Veglia, F., Holdt, L. M., Beutner, F., Gansevoort, R. T., Navis, G. J., Mateo Leach, I., Breitling, L. P., Brenner, H., Thiery, J., Dallmeier, D., Franco-Cereceda, A., Boer, J. M. A., Stephens, J. W., Hofker, M. H., Tedgui, A., Hofman, A., Uitterlinden, A. G., Adamkova, V., Pitha, J., Onland-Moret, N. C., Cramer, M. J., Nathoe, H. M., Spiering, W., Klungel, O. H., Kumari, M., Whincup, P. H., Morrow, D. A., Braund, P. S., Hall, A. S., Olsson, A. G., Doevendans, P. A., Trip, M. D., Tobin, M. D., Hamsten, A., Watkins, H., Koenig, W., Nicolaides, A. N., Teupser, D., Day, I. N. M., Carlquist, J. F., Gaunt, T. R., Ford, I., Sattar, N., Tsimikas, S., Schwartz, G. G., Lawlor, D. A., Morris, R. W., Sandhu, M. S., Poledne, R., Maitland-van der Zee, A. H., Khaw, K-T., Keating, B. J., van der Harst, P., Price, J. F., Mehta, S. R., Yusuf, S., Witteman, J. C. M., Franco, O. H., Jukema, J. W., de Knijff, P., Tybjaerg-Hansen, A., Rader, D. J., Farrall, M., Samani, N. J., Kivimaki, M., Fox, K. A. A., Humphries, S. E., Anderson, J. L., Boekholdt, S. M., Palmer, T. M., Eriksson, P., Paré, G., Hingorani, A. D., Sabatine, M. S., Mallat, Z., Casas, J. P. & Talmud, P. J., 19/11/2013, In : Journal of the American College of Cardiology. 62, 21, p. 1966-1976 11 p.

    Research output: Contribution to journalJournal article

  4. Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

    Palmer, T. M., Nordestgaard, B. G., Benn, M., Tybjærg-Hansen, A., Davey Smith, G., Lawlor, D. A. & Timpson, N. J., 18/07/2013, In : BMJ. 347, 10 p., f4262.

    Research output: Contribution to journalJournal article

  5. Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies

    Harbord, R. M., Didelez, V., Palmer, T. M., Meng, S., Sterne, J. A. C. & Sheehan, N. A., 30/03/2013, In : Statistics in Medicine. 32, 7, p. 1246-1258 13 p.

    Research output: Contribution to journalJournal article

  6. Re: "credible mendelian randomization studies: approaches for evaluating the instrumental variable assumptions"

    Palmer, T. M., Ramsahai, R. R., Lawlor, D. A., Sheehan, N. A. & Didelez, V., 1/09/2012, In : American Journal of Epidemiology. 176, 5, p. 457-458; author reply 458 2 p.

    Research output: Contribution to journalJournal article

  7. Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis

    Theodoratou, E., Palmer, T., Zgaga, L., Farrington, S. M., McKeigue, P., Din, F. V. N., Tenesa, A., Davey-Smith, G., Dunlop, M. G. & Campbell, H., 6/06/2012, In : PLoS ONE. 7, 6, 10 p., e37662.

    Research output: Contribution to journalJournal article

  8. Using multiple genetic variants as instrumental variables for modifiable risk factors

    Palmer, T. M., Lawlor, D. A., Harbord, R. M., Sheehan, N. A., Tobias, J. H., Timpson, N. J., Davey Smith, G. & Sterne, J. A. C., 06/2012, In : Statistical Methods in Medical Research. 21, 3, p. 223-242 20 p.

    Research output: Contribution to journalJournal article

  9. The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

    Nordestgaard, B. G., Palmer, T. M., Benn, M., Zacho, J., Tybjaerg-Hansen, A., Davey Smith, G. & Timpson, N. J., 1/05/2012, In : PLoS Medicine. 9, 5, 13 p., e1001212.

    Research output: Contribution to journalJournal article

  10. Smoking is associated with, but does not cause, depressed mood in pregnancy--a mendelian randomization study

    Lewis, S. J., Araya, R., Smith, G. D., Freathy, R., Gunnell, D., Palmer, T. & Munafò, M., 07/2011, In : PLoS ONE. 6, 7, 5 p., e21689.

    Research output: Contribution to journalJournal article

  11. Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses

    Palmer, T. M., Sterne, J. A. C., Harbord, R. M., Lawlor, D. A., Sheehan, N. A., Meng, S., Granell, R., Smith, G. D. & Didelez, V., 15/06/2011, In : American Journal of Epidemiology. 173, 12, p. 1392-1403 12 p.

    Research output: Contribution to journalJournal article

More results »