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Results for Mice, Knockout

Publications & Outputs

  1. Type I interferon is required for T helper (Th) 2 induction by dendritic cells

    Webb, L. M., Lundie, R. J., Borger, J. G., Brown, S. L., Connor, L. M., Cartwright, A. N., Dougall, A. M., Wilbers, R. H., Cook, P. C., Jackson-Jones, L. H., Phythian-Adams, A. T., Johansson, C., Davis, D. M., Dewals, B. G., Ronchese, F. & MacDonald, A. S., 15/08/2017, In : EMBO Journal. 36, 16, p. 2404-2418 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha

    Jackson-Jones, L. H., Rückerl, D., Svedberg, F., Duncan, S., Maizels, R. M., Sutherland, T. E., Jenkins, S. J., McSorley, H. J., Bénézech, C., MacDonald, A. S. & Allen, J. E., 10/2016, In : European Journal of Immunology. 46, 10, p. 2311-2321 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Inflammation-induced formation of fat-associated lymphoid clusters

    Bénézech, C., Luu, N-T., Walker, J. A., Kruglov, A. A., Loo, Y., Nakamura, K., Zhang, Y., Nayar, S., Jones, L. H., Flores-Langarica, A., McIntosh, A., Marshall, J., Barone, F., Besra, G., Miles, K., Allen, J. E., Gray, M., Kollias, G., Cunningham, A. F., Withers, D. R. & 6 others, Toellner, K. M., Jones, N. D., Veldhoen, M., Nedospasov, S. A., McKenzie, A. N. J. & Caamaño, J. H., 29/06/2015, In : Nature Immunology. 16, 8, p. 819-828 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

    Cook, P. C., Owen, H., Deaton, A. M., Borger, J. G., Brown, S. L., Clouaire, T., Jones, G-R., Jones, L. H., Lundie, R. J., Marley, A. K., Morrison, V. L., Phythian-Adams, A. T., Wachter, E., Webb, L. M., Sutherland, T. E., Thomas, G. D., Grainger, J. R., Selfridge, J., McKenzie, A. N. J., Allen, J. E. & 5 others, Fagerholm, S. C., Maizels, R. M., Ivens, A. C., Bird, A. & MacDonald, A. S., 24/04/2015, In : Nature Communications. 6, 11 p., 6920.

    Research output: Contribution to journalJournal articlepeer-review

  5. LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis

    Nakamura, T., Hamuro, J., Takaishi, M., Simmons, S., Maruyama, K., Zaffalon, A., Bentley, A. J., Kawasaki, S., Nagata-Takaoka, M., Fullwood, N. J., Itami, S., Sano, S., Ishii, M., Barrandon, Y. & Kinoshita, S., 2/01/2014, In : Journal of Clinical Investigation. 124, 1, p. 385-397 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia

    Douvaras, P., Mort, R. L., Edwards, D., Ramaesh, K., Dhillon, B., Morley, S. D., Hill, R. E. & West, J. D., 13/08/2013, In : PLoS ONE. 8, 8, 18 p., e71117.

    Research output: Contribution to journalJournal articlepeer-review

  7. IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation

    Sandig, H., Jobbings, C. E., Roldan, N. G., Whittingham-Dowd, J. K., Orinska, Z., Takeuchi, O., Akira, S. & Bulfone-Paus, S., 04/2013, In : European Journal of Immunology. 43, 4, p. 979-988 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion

    Worthington, J. J., Samuelson, L. C., Grencis, R. K. & McLaughlin, J. T., 17/01/2013, In : PLoS Pathogens. 9, 1, 8 p., e1003122.

    Research output: Contribution to journalJournal articlepeer-review

  9. Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity

    Worthington, J. J., Klementowicz, J. E., Rahman, S., Czajkowska, B. I., Smedley, C., Waldmann, H., Sparwasser, T., Grencis, R. K. & Travis, M. A., 2013, In : PLoS Pathogens. 9, 10, 12 p., e1003675.

    Research output: Contribution to journalJournal articlepeer-review

  10. P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

    Lindsay, C. R., Lawn, S., Campbell, A. D., Faller, W. J., Rambow, F., Mort, R. L., Timpson, P., Li, A., Cammareri, P., Ridgway, R. A., Morton, J. P., Doyle, B., Hegarty, S., Rafferty, M., Murphy, I. G., McDermott, E. W., Sheahan, K., Pedone, K., Finn, A. J., Groben, P. A. & 14 others, Thomas, N. E., Hao, H., Carson, C., Norman, J. C., Machesky, L. M., Gallagher, W. M., Jackson, I. J., Van Kempen, L., Beermann, F., Der, C., Larue, L., Welch, H. C., Ozanne, B. W. & Sansom, O. J., 22/11/2011, In : Nature Communications. 2, 9 p., 555.

    Research output: Contribution to journalJournal articlepeer-review

  11. Intestinal dendritic cells specialize to activate transforming growth factor-β and induce Foxp3+ regulatory T cells via integrin αvβ8

    Worthington, J. J., Czajkowska, B. I., Melton, A. C. & Travis, M. A., 11/2011, In : Gastroenterology. 141, 5, p. 1802-1812 11 p.

    Research output: Contribution to journalJournal articlepeer-review

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