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Research

Results for alpha-Synuclein

Publications & Outputs

  1. Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases

    Muñoz-Lobato, F., Rodríguez-Palero, M. J., Naranjo-Galindo, F. J., Shephard, F., Gaffney, C. J., Szewczyk, N. J., Hamamichi, S., Caldwell, K. A., Caldwell, G. A., Link, C. D. & Miranda-Vizuete, A., 10/01/2014, In: Antioxidants and Redox Signaling. 20, 2, p. 217-235 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Parkinson disease: progress towards a molecular biomarker for Parkinson disease

    Foulds, P., Mann, D. M. A., Mitchell, J. D. & Allsop, D., 07/2010, In: Nature Reviews Neurology. 6, 7, p. 359-361 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Evaluation of beta-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation

    Madine, J., Wang, X., Brown, D. R. & Middleton, D. A., 17/08/2009, In: June 2002. ISSN 1460-4582. 10, 12, p. 1982-7 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Inhibitors of protein aggregation and toxicity

    Amijee, H., Madine, J., Middleton, D. A. & Doig, A. J., 08/2009, In: Biochemical Society Transactions. 37, Pt 4, p. 692-6 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Exploiting a (13)C-labelled heparin analogue for in situ solid-state NMR investigations of peptide-glycan interactions within amyloid fibrils

    Madine, J., Clayton, J. C., Yates, E. A. & Middleton, D. A., 7/06/2009, In: Organic and Biomolecular Chemistry . 7, 11, p. 2414-20 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies

    Paleologou, K. E., Kragh, C. L., Mann, D. M. A., Salem, S. A., Al-Shami, R., Allsop, D., Hassan, A. H., Jensen, P. H. & El-Agnaf, O. M. A., 2009, In: Brain. 132, 4, p. 1093-1101 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. The effects of alpha-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron microscopy

    Madine, J., Hughes, E., Doig, A. J. & Middleton, D. A., 09/2008, In: Molecular Membrane Biology. 25, 6-7, p. 518-27 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Design of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR

    Madine, J., Doig, A. J. & Middleton, D. A., 25/06/2008, In: Journal of the American Chemical Society. 130, 25, p. 7873-81 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. An investigation into the lipid-binding properties of α-, β- and γ-synucleins in human brain and cerebrospinal fluid

    Salem, S. A., Allsop, D., Mann, D. M. A., Tokuda, T. & El-Agnaf, O. M. A., 19/09/2007, In: Experimental Brain Research. 1170, p. 103-111 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review