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Research

Dr Andrew Fielding

Senior Lecturer in Cancer Research

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  1. 2022
  2. Published

    Aggressive uveal melanoma displays a high degree of centrosome amplification, opening the door to therapeutic intervention

    Sabat‐Pośpiech, D., Fabian‐Kolpanowicz, K., Kalirai, H., Kipling, N., Coupland, S. E., Coulson, J. M. & Fielding, A. B., 31/07/2022, In: The Journal of Pathology: Clinical Research. 8, 4, p. 383-394 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2019
  4. Published

    Targeting centrosome amplification, an Achilles' heel of cancer

    Sabat-Pośpiech, D., Fabian-Kolpanowicz, K., Prior, I. A., Coulson, J. M. & Fielding, A. B., 31/10/2019, In: Biochemical Society Transactions. 47, 5, p. 1209-1222 14 p.

    Research output: Contribution to Journal/Magazine › Review article › peer-review

  5. 2018
  6. Published

    Altered Nuclear Expression of the Deubiquitylase BAP1 Cannot be Used as a Prognostic Marker for Canine Melanoma

    Jama, N., Farquhar, N., Butt, Z., Coupland, S. E., Sacco, J. J., Scase, T., Fielding, A. B., Coulson, J. M., Kalirai, H. & Killick, D. R., 07/2018, In: Journal of Comparative Pathology. 162, p. 50-58 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity

    Fielding, A. B., Concannon, M., Darling, S., Rusilowicz-Jones, E. V., Sacco, J. J., Prior, I. A., Clague, M. J., Urbé, S. & Coulson, J. M., 04/2018, In: Oncogene. 37, p. 2326-2342 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. 2017
  9. Published

    Regulation of the cell cycle and centrosome biology by deubiquitylases

    Darling, S., Fielding, A. B., Sabat-Pośpiech, D., Prior, I. A. & Coulson, J. M., 15/10/2017, In: Biochemical Society Transactions. 45, 5, p. 1125-1136 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. 2014
  11. Published

    Isolating HeLa cell fractions enriched for clathrin-coated vesicles

    Borner, G. H. H. & Fielding, A. B., 3/11/2014, In: Cold Spring Harbor Protocols. 2014, 11, p. 1184-1187 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Isolation of clathrin-coated vesicles from tissue culture cells

    Borner, G. H. H. & Fielding, A. B., 3/11/2014, In: Cold Spring Harbor Protocols. 2014, 11, p. 1136-1138 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Using in-gel digestion and an Orbitrap mass spectrometer to analyze the proteome of clathrin-coated vesicles

    Borner, G. H. H. & Fielding, A. B., 3/11/2014, In: Cold Spring Harbor Protocols. 2014, 11, p. 1188-1191 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Using in-solution digestion, peptide fractionation, and a Q exactive mass spectrometer to analyze the proteome of clathrin-coated vesicles

    Borner, G. H. H. & Fielding, A. B., 3/11/2014, In: Cold Spring Harbor Protocols. 2014, 11, p. 1192-1195 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis

    Kaur, S., Fielding, A. B., Gassner, G., Carter, N. J. & Royle, S. J., 18/02/2014, In: eLife. 3, 17 p., e00829.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. 2013
  17. Published

    Identification of novel small molecule inhibitors of centrosome clustering in cancer cells

    Kawamura, E., Fielding, A. B., Kannan, N., Balgi, A., Eaves, C. J., Roberge, M. & Dedhar, S., 10/2013, In: Oncotarget. 4, 10, p. 1763-1776 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Mitotic inhibition of clathrin-mediated endocytosis

    Fielding, A. B., 09/2013, In: Cellular and Molecular Life Sciences : CMLS. 70, 18, p. 3423-3433 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Integrin-linked kinase regulates interphase and mitotic microtubule dynamics

    Lim, S., Kawamura, E., Fielding, A. B., Maydan, M. & Dedhar, S., 21/01/2013, In: PLoS ONE. 8, 1, 11 p., e53702.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. 2012
  21. Published

    Clathrin-mediated endocytosis is inhibited during mitosis

    Fielding, A. B., Willox, A. K., Okeke, E. & Royle, S. J., 24/04/2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 17, p. 6572-6577 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. 2011
  23. Published

    A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells

    Fielding, A. B., Lim, S., Montgomery, K., Dobreva, I. & Dedhar, S., 3/02/2011, In: Oncogene. 30, 5, p. 521-534 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. 2009
  25. Published

    The mitotic functions of integrin-linked kinase

    Fielding, A. B. & Dedhar, S., 06/2009, In: Cancer Metastasis Reviews. 28, 1-2, p. 99-111 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. 2008
  27. Published

    Integrin-linked kinase--essential roles in physiology and cancer biology

    McDonald, P. C., Fielding, A. B. & Dedhar, S., 1/10/2008, In: Journal of Cell Science. 121, 19, p. 3121-3132 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Beyond focal adhesions: integrin-linked kinase associates with tubulin and regulates mitotic spindle organization

    Fielding, A. B., Dobreva, I. & Dedhar, S., 1/07/2008, In: Cell Cycle. 7, 13, p. 1899-1906 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  29. Published

    Mapping the integrin-linked kinase interactome using SILAC

    Dobreva, I., Fielding, A., Foster, L. J. & Dedhar, S., 04/2008, In: Journal of Proteome Research. 7, 4, p. 1740-1749 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. Published

    Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

    Fielding, A. B., Dobreva, I., McDonald, P. C., Foster, L. J. & Dedhar, S., 25/02/2008, In: Journal of Cell Biology. 180, 4, p. 681-9 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  31. 2005
  32. Published

    Membrane traffic in cytokinesis

    Matheson, J., Yu, X., Fielding, A. B. & Gould, G. W., 12/2005, In: Biochemical Society Transactions. 33, Pt 6, p. 1290-1294 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  33. Published

    Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis

    Schonteich, E., Fielding, A. B., Matheson, J., Wilson, G., Yu, X., Hickson, G. R. X., Srivastava, S., Baldwin, S. A., Prekeris, R. & Gould, G. W., 5/10/2005, In: EMBO Journal. 24, 19, p. 3389-99 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  34. Published

    The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis

    Wilson, G. M., Fielding, A. B., Simon, G. C., Yu, X., Andrews, P. D., Hames, R. S., Frey, A. M., Peden, A. A., Gould, G. W. & Prekeris, R., 02/2005, In: Molecular Biology of the Cell. 16, 2, p. 849-860 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  35. 2003
  36. Published

    Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout

    Hickson, G. R. X., Matheson, J., Riggs, B., Maier, V. H., Fielding, A. B., Prekeris, R., Sullivan, W., Barr, F. A. & Gould, G. W., 07/2003, In: Molecular Biology of the Cell. 14, 7, p. 2908-2920 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  37. 2000
  38. Published

    Structure-function relationships of a novel bacterial toxin, hemolysin E. The role of alpha G

    Atkins, A., Wyborn, N. R., Wallace, A. J., Stillman, T. J., Black, L. K., Fielding, A. B., Hisakado, M., Artymiuk, P. J. & Green, J., 29/12/2000, In: Journal of Biological Chemistry. 275, 52, p. 41150-41155 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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