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Supervised by

Anthony Aggidis

Research student

Anthony Aggidis

Furness Building Lancaster University Bailrigg Lancaster LA1 4YG


United Kingdom

Current Research

Prof David Allsop’s research group have recently developed a novel retro-inverted peptide-based amyloid beta aggregation inhibitor that may be useful for treatment of Alzheimer’s disease. Under Prof Allsop’s supervision my research will be investigating how selective the free peptide and nanoparticle versions of this inhibitor are by testing interactions with protein aggregation systems other than amyloid beta, such as Tau, which forms tangles consisting of paired helical filaments.  If the peptide based inhibitors also prevent tangle formation, my research will focus on the mechanism behind this. Otherwise the research will investigate and attempt to find the critical region in tau to make tangle-specific peptide based inhibitors

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