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Research

Professor Christian Holscher

Formerly at Lancaster University

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  1. 2022
  2. Published

    Beyond appetite: Acylated ghrelin as a learning, memory and fear behavior-modulating hormone

    Reich, N. & Hölscher, C., 31/12/2022, In: Neuroscience and Biobehavioral Reviews. 143, 27 p., 104952.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Entropy of city street networks linked to future spatial navigation ability

    Coutrot, A., Manley, E., Goodroe, S., Gahnstrom, C., Filomena, G., Yesiltepe, D., Conroy-Dalton, R., Wiener, J. M., Hölscher, C., Hornberger, M. & Spiers, H. J., 7/04/2022, In: Nature. 604, 7904, p. 104–110 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. 2021
  5. Published

    Glucagon like peptide-1 receptor agonists as neuroprotective agents for ischemic stroke: a systematic scoping review

    Maskery, M. P., Holscher, C., Jones, S. P., Price, C. I., Strain, W. D., Watkins, C. L., Werring, D. J. & Emsley, H. C. A., 1/01/2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 1, p. 14-30 17 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. 2020
  7. Published

    Acylated Ghrelin as a Multi-Targeted Therapy for Alzheimer's and Parkinson's Disease.

    Reich, N. & Hölscher, C., 14/12/2020, In: Frontiers in Neuroscience. 14, 35 p., 614828.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. 2019
  9. Published

    DA-JC1 improves learning and memory by antagonizing Aβ31-35-induced circadian rhythm disorder

    Wang, L., Zhang, R., Hou, X., Wang, C., Guo, S., Ning, N., Sun, C., Yuan, Y., Li, L., Hölscher, C. & Wang, X., 11/02/2019, In: Molecular Brain. 12, 1, 14 p., 12.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Liraglutide and a lipidized analog of prolactin-releasing peptide show neuroprotective effects in a mouse model of β-amyloid pathology

    Holubová, M., Hrubá, L., Popelová, A., Bencze, M., Pražienková, V., Gengler, S., Kratochvílová, H., Haluzík, M., Železná, B., Kuneš, J., Hölscher, C. & Maletínská, L., 01/2019, In: Neuropharmacology. 144, p. 377-387 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. 2018
  12. Published

    Prolonged Drug-Releasing Fibers Attenuate Alzheimer's Disease-like Pathogenesis

    Salles, G. N., Calió, M. L., Afewerki, S., Pacheco-Soares, C., Porcionatto, M., Hölscher, C. & Lobo, A. O., 31/10/2018, In: ACS Applied Materials and Interfaces. 10, 43, p. 36693-36702 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    The Novel DA-CH3 Dual Incretin Restores Endoplasmic Reticulum Stress and Autophagy Impairments to Attenuate Alzheimer-Like Pathology and Cognitive Decrements in the APPSWE/PS1ΔE9 Mouse Model

    Panagaki, T., Gengler, S. & Hölscher, C., 16/10/2018, In: Journal of Alzheimer's Disease. 66, 1, p. 195-218 24 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model

    Zhang, L., Zhang, L., Li, L. & Hölscher, C., 10/2018, In: Neuropeptides. 71, p. 70-80 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Liraglutide Attenuates the Depressive- and Anxiety-like Behaviour in the Corticosterone Induced Depression Model Via Improving Hippocampal Neural Plasticity

    Weina, H., Yuhu, N., Hölscher, C., Birong, L., Feiyu, S. & Le, W., 1/09/2018, In: Brain Research. 1694, p. 55-62 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Are Alzheimer's disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones?

    Hölscher, C., De Felice, F. G., Greig, N. & Ferreira, S. T., 1/07/2018, In: Neuropharmacology. 136, Part B, p. 159 1 p.

    Research output: Contribution to Journal/Magazine › Editorial › peer-review

  17. Published

    Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models

    Hölscher, C., 1/07/2018, In: Neuropharmacology. 136, Part B, p. 251-259 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of Alzheimer's disease

    Cao, Y., Hölscher, C., Hu, M-M., Wang, T., Zhao, F., Bai, Y., Zhang, J., Wu, M-N. & Qi, J-S., 15/05/2018, In: European Journal of Pharmacology. 827, p. 215-226 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Two novel dual GLP-1/GIP receptor agonists are neuroprotective in the MPTP mouse model of Parkinson's disease

    Feng, P., Zhang, X., Li, D., Ji, C., Yuan, Z., Wang, R., Xue, G., Li, G. & Hölscher, C., 1/05/2018, In: Neuropharmacology. 133, p. 385-394 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus

    Wang, R-F., Xue, G-F., Hölscher, C., Tian, M-J., Feng, P., Zheng, J-Y. & Li, D-F., 05/2018, In: Epilepsy Research. 142, p. 45-52 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    GLP-1 receptor agonists show neuroprotective effects in animal models of diabetes

    Gault, V. A. & Hölscher, C., 02/2018, In: Peptides. 100, p. 101-107 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease

    Tai, J., Liu, W., Li, Y., Li, L. & Hölscher, C., 1/01/2018, In: Brain Research. 1678, p. 64-74 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. 2017
  24. Published

    Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells

    Panagaki, T., Michael, M. & Hölscher, C., 23/11/2017, In: Scientific Reports. 7, 16 p., 16158.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    A novel bioresorbable device as a controlled release system for protecting cells from oxidative stress from Alzheimer’s Disease

    Salles, G. N., Pereira, F. A. D. S., Pacheco-Soares, C., Marciano, F. R., Holscher, C., Webster, T. J. & Lobo, A. O., 11/2017, In: Molecular Neurobiology. 54, 9, p. 6827-6838 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    A novel GLP-1/GIP dual agonist is more effective than liraglutide in reducing inflammation and enhancing GDNF release in the MPTP mouse model of Parkinson's disease

    Yuan, Z., Li, D., Feng, P., Xue, G., Ji, C., Li, G. & Hölscher, C., 5/10/2017, In: European Journal of Pharmacology. 812, p. 82-90 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  27. Published

    Integrating microRNA and messenger RNA expression profiles in a rat model of deep vein thrombosis

    Jin, Q-Q., Sun, J-H., Du, Q-X., Lu, X-J., Zhu, X-Y., Fan, H-L., Holscher, C. & Wang, Y-Y., 10/2017, In: International Journal of Molecular Medicine. 40, 4, p. 1019-1028 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Therapeutic Potential of Baicalein in Alzheimer's Disease and Parkinson's Disease

    Li, Y., Zhao, J. & Holscher, C., 08/2017, In: CNS Drugs. 31, 8, p. 639-652 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  29. Published

    A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model

    Shi, L., Zhang, Z. & Hölscher, C., 1/06/2017, In: Behavioural Brain Research. 327, p. 65-74 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. Published

    A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease

    Jalewa, J., Sharma, M. K., Gengler, S. & Hölscher, C., 1/05/2017, In: Neuropharmacology. 117, p. 238-248 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  31. Published

    GLP-1/GIP/Gcg三受体激动剂改善3xTg-AD小鼠认知行为和病理特征研究

    Jiao, J-J., Hölscher, C., Li, T., Dong, X-F., Qu, X-S., Cao, Y., Wu, M-N., Wang, Z-J. & Qi, J-S., 25/04/2017, In: Acta Physiologica Sinica. 69, 2, p. 135-145 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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