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Professor Christian Holscher

Formerly at Lancaster University

  1. 2019
  2. Published

    DA-JC1 improves learning and memory by antagonizing Aβ31-35-induced circadian rhythm disorder

    Wang, L., Zhang, R., Hou, X., Wang, C., Guo, S., Ning, N., Sun, C., Yuan, Y., Li, L., Hölscher, C. & Wang, X., 11/02/2019, In : Molecular Brain. 12, 1, 14 p., 12.

    Research output: Contribution to journalJournal article

  3. Published

    Liraglutide and a lipidized analog of prolactin-releasing peptide show neuroprotective effects in a mouse model of β-amyloid pathology

    Holubová, M., Hrubá, L., Popelová, A., Bencze, M., Pražienková, V., Gengler, S., Kratochvílová, H., Haluzík, M., Železná, B., Kuneš, J., Hölscher, C. & Maletínská, L., 01/2019, In : Neuropharmacology. 144, p. 377-387 11 p.

    Research output: Contribution to journalJournal article

  4. 2018
  5. Published

    Prolonged Drug-Releasing Fibers Attenuate Alzheimer's Disease-like Pathogenesis

    Salles, G. N., Calió, M. L., Afewerki, S., Pacheco-Soares, C., Porcionatto, M., Hölscher, C. & Lobo, A. O., 31/10/2018, In : ACS Applied Materials and Interfaces. 10, 43, p. 36693-36702 10 p.

    Research output: Contribution to journalJournal article

  6. Published

    The Novel DA-CH3 Dual Incretin Restores Endoplasmic Reticulum Stress and Autophagy Impairments to Attenuate Alzheimer-Like Pathology and Cognitive Decrements in the APPSWE/PS1ΔE9 Mouse Model

    Panagaki, T., Gengler, S. & Hölscher, C., 16/10/2018, In : Journal of Alzheimer's Disease. 66, 1, p. 195-218 24 p.

    Research output: Contribution to journalJournal article

  7. Published

    Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model

    Zhang, L., Zhang, L., Li, L. & Hölscher, C., 10/2018, In : Neuropeptides. 71, p. 70-80 11 p.

    Research output: Contribution to journalJournal article

  8. Published

    Liraglutide Attenuates the Depressive- and Anxiety-like Behaviour in the Corticosterone Induced Depression Model Via Improving Hippocampal Neural Plasticity

    Weina, H., Yuhu, N., Hölscher, C., Birong, L., Feiyu, S. & Le, W., 1/09/2018, In : Brain Research. 1694, p. 55-62 8 p.

    Research output: Contribution to journalJournal article

  9. Published

    Are Alzheimer's disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones?

    Hölscher, C., De Felice, F. G., Greig, N. & Ferreira, S. T., 1/07/2018, In : Neuropharmacology. 136, Part B, p. 159 1 p.

    Research output: Contribution to journalEditorial

  10. Published

    Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models

    Hölscher, C., 1/07/2018, In : Neuropharmacology. 136, Part B, p. 251-259 9 p.

    Research output: Contribution to journalJournal article

  11. Published

    DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of Alzheimer's disease

    Cao, Y., Hölscher, C., Hu, M-M., Wang, T., Zhao, F., Bai, Y., Zhang, J., Wu, M-N. & Qi, J-S., 15/05/2018, In : European Journal of Pharmacology. 827, p. 215-226 12 p.

    Research output: Contribution to journalJournal article

  12. Published

    Two novel dual GLP-1/GIP receptor agonists are neuroprotective in the MPTP mouse model of Parkinson's disease

    Feng, P., Zhang, X., Li, D., Ji, C., Yuan, Z., Wang, R., Xue, G., Li, G. & Hölscher, C., 1/05/2018, In : Neuropharmacology. 133, p. 385-394 10 p.

    Research output: Contribution to journalJournal article

  13. Published

    Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus

    Wang, R-F., Xue, G-F., Hölscher, C., Tian, M-J., Feng, P., Zheng, J-Y. & Li, D-F., 05/2018, In : Epilepsy Research. 142, p. 45-52 8 p.

    Research output: Contribution to journalJournal article

  14. Published

    GLP-1 receptor agonists show neuroprotective effects in animal models of diabetes

    Gault, V. A. & Hölscher, C., 02/2018, In : Peptides. 100, p. 101-107 7 p.

    Research output: Contribution to journalJournal article

  15. Published

    Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease

    Tai, J., Liu, W., Li, Y., Li, L. & Hölscher, C., 1/01/2018, In : Brain Research. 1678, p. 64-74 11 p.

    Research output: Contribution to journalJournal article

  16. 2017
  17. Published

    Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells

    Panagaki, T., Michael, M. & Hölscher, C., 23/11/2017, In : Scientific Reports. 7, 16 p., 16158.

    Research output: Contribution to journalJournal article

  18. Published

    A novel bioresorbable device as a controlled release system for protecting cells from oxidative stress from Alzheimer’s Disease

    Salles, G. N., Pereira, F. A. D. S., Pacheco-Soares, C., Marciano, F. R., Holscher, C., Webster, T. J. & Lobo, A. O., 11/2017, In : Molecular Neurobiology. 54, 9, p. 6827-6838 12 p.

    Research output: Contribution to journalJournal article

  19. Published

    A novel GLP-1/GIP dual agonist is more effective than liraglutide in reducing inflammation and enhancing GDNF release in the MPTP mouse model of Parkinson's disease

    Yuan, Z., Li, D., Feng, P., Xue, G., Ji, C., Li, G. & Hölscher, C., 5/10/2017, In : European Journal of Pharmacology. 812, p. 82-90 9 p.

    Research output: Contribution to journalJournal article

  20. Published

    Integrating microRNA and messenger RNA expression profiles in a rat model of deep vein thrombosis

    Jin, Q-Q., Sun, J-H., Du, Q-X., Lu, X-J., Zhu, X-Y., Fan, H-L., Holscher, C. & Wang, Y-Y., 10/2017, In : International Journal of Molecular Medicine. 40, 4, p. 1019-1028 10 p.

    Research output: Contribution to journalJournal article

  21. Published

    Therapeutic Potential of Baicalein in Alzheimer's Disease and Parkinson's Disease

    Li, Y., Zhao, J. & Holscher, C., 08/2017, In : CNS Drugs. 31, 8, p. 639-652 14 p.

    Research output: Contribution to journalJournal article

  22. Published

    A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model

    Shi, L., Zhang, Z. & Hölscher, C., 1/06/2017, In : Behavioural Brain Research. 327, p. 65-74 10 p.

    Research output: Contribution to journalJournal article

  23. Published

    A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease

    Jalewa, J., Sharma, M. K., Gengler, S. & Hölscher, C., 1/05/2017, In : Neuropharmacology. 117, p. 238-248 11 p.

    Research output: Contribution to journalJournal article

  24. Published

    GLP-1/GIP/Gcg三受体激动剂改善3xTg-AD小鼠认知行为和病理特征研究

    Jiao, J-J., Hölscher, C., Li, T., Dong, X-F., Qu, X-S., Cao, Y., Wu, M-N., Wang, Z-J. & Qi, J-S., 25/04/2017, In : Acta Physiologica Sinica. 69, 2, p. 135-145 11 p.

    Research output: Contribution to journalJournal article

  25. Published

    D-Ala2-GIP-glu-PAL is neuroprotective in a chronic Parkinson's disease mouse model and increases BNDF expression while reducing neuroinflammation and lipid peroxidation

    Li, Y., Liu, W., Li, L. & Holscher, C., 15/02/2017, In : European Journal of Pharmacology. 797, p. 162-172 11 p.

    Research output: Contribution to journalJournal article

  26. Published

    Lixisenatide attenuates the detrimental effects of amyloid β protein on spatial working memory and hippocampal neurons in rats

    Cai, H-Y., Wang, Z-J., Holscher, C., Yuan, L., Zhang, J., Sun, P., Li, J., Yang, W., Wu, M-N. & Qi, J-S., 1/02/2017, In : Behavioural Brain Research. 318, p. 28-35 8 p.

    Research output: Contribution to journalJournal article

  27. Published

    Levo-tetrahydropalmatine inhibits the acquisition of ketamine-induced conditioned place preference by regulating the expression of ERK and CREB phosphorylation in rats

    Du, Y., Du, L., Cao, J., Holscher, C., Feng, Y., Su, H., Wang, Y. & Yun, K-M., 15/01/2017, In : Behavioural Brain Research. 317, p. 367-373 7 p.

    Research output: Contribution to journalJournal article

  28. Published

    Therapeutic potential of flavonoids in spinal cord injury

    Zhang, P., Holscher, C. & Ma, X., 01/2017, In : Reviews in the Neurosciences. 28, 1, p. 87-101 15 p.

    Research output: Contribution to journalJournal article

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