Home > Research > Researchers > Professor David Allsop > Publications

Professor David Allsop

Professor

  1. 2019
  2. Forthcoming

    Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS: A comprehensive analysis on diagnostic and prognostic significance of plasma and CSF NfL, TDP-43, and tau

    Kasai, T., Kojima, Y., Ohmichi, T., Tatebe, H., Tsuji, Y., Noto, Y., Kitani-Morii, F., Shinomoto, M., Allsop, D., Mizuno, T. & Tokuda, T., 21/10/2019, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

    Research output: Contribution to journalJournal article

  3. E-pub ahead of print

    Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis

    Martin, G. P., McDonald, K. R., Allsop, D., Diggle, P. J. & Leroi, I., 15/10/2019, In : Journal of Neurology. 14 p.

    Research output: Contribution to journalJournal article

  4. Published

    Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

    Shinomoto, M., Kasai, T., Tatebe, H., Kondo, M., Ohmichi, T., Morimoto, M., Chiyonobu, T., Terada, N., Allsop, D., Yokota, I., Mizuno, T. & Tokuda, T., 5/04/2019, In : PLoS ONE. 14, 4, 13 p., e0211575.

    Research output: Contribution to journalJournal article

  5. 2018
  6. Published

    Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer’s disease

    Paraskevaidi, M., Morais, C., Freitas, D., Lima, K., Mann, D., Allsop, D., Martin-Hirsch, P. & Martin, F. L., 21/12/2018, In : Analyst. 143, 24, p. 5959-5964 6 p.

    Research output: Contribution to journalJournal article

  7. Published

    Liposome delivery systems for the treatment of Alzheimer’s disease

    Ross, C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 12/12/2018, In : International Journal of Nanomedicine. 2018, 13, p. 8507-8522 16 p.

    Research output: Contribution to journalJournal article

  8. Published

    Raman spectroscopy to diagnose Alzheimer's disease and dementia with Lewy bodies in blood

    Paraskevaidi, M., Morais, C., Halliwell, D., Mann, D., Allsop, D., Martin-Hirsch, P. & Martin, F. L., 2018, In : ACS Chemical Neuroscience. 9, 11, p. 2786–2794 9 p.

    Research output: Contribution to journalJournal article

  9. Published

    Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease

    Allsop, D., Aggidis, A., Fullwood, N. J., Taylor, M. N., Foulds, P., Vincent, S. & Dale, M., 2018, In : Journal of Prevention of Alzheimer's Disease. 5, Suppl 1, p. S15-S16 2 p.

    Research output: Contribution to journalMeeting abstract

  10. 2017
  11. Published

    Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes

    Obasse, I. C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 6/12/2017, In : Interface Focus. 7, 6, 11 p., 20160127.

    Research output: Contribution to journalJournal article

  12. Published

    Increased levels of plasma total tau in adult Down syndrome

    Kasai, T., Tatebe, H., Kondo, M., Ishii, R., Ohmichi, T., Yeung, W. T. E., Morimoto, M., Chiyonobu, T., Terada, N., Allsop, D., Nakagawa, M., Mizuno, T. & Tokuda, T., 30/11/2017, In : PLoS ONE. 12, 11, 12 p., e0188802.

    Research output: Contribution to journalJournal article

  13. Published

    A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation

    Allsop, D., Taylor, M. N., Fullwood, N. J., Michael, M., Aggidis, A., Vincent, S. & Dale, M., 1/11/2017, In : Journal of Prevention of Alzheimer's Disease. 4, 4, p. 385-386 2 p.

    Research output: Contribution to journalMeeting abstract

  14. Published

    α-Synuclein interacts with lipoproteins in plasma

    Nouri Emamzadeh, F. & Allsop, D., 10/2017, In : Journal of Molecular Neuroscience . 63, 2, p. 165-172 8 p.

    Research output: Contribution to journalJournal article

  15. Published

    Differential diagnosis of Alzheimer’s disease using spectrochemical analysis of blood

    Paraskevaidi, M., Morais, C., Lima, K., Snowden, J., Saxon, J., Richardson, A., Jones, M., Mann, D., Allsop, D., Martin-Hirsch, P. & Martin, F., 19/09/2017, In : Proceedings of the National Academy of Sciences of the USA. 114, 38, p. E7929–E7938 10 p.

    Research output: Contribution to journalJournal article

  16. Published

    Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and Down syndrome

    Tatebe, H., Kasai, T., Ohmichi, T., Kishi, Y., Kakeya, T., Waragai, M., Kondo, M., Allsop, D. & Tokuda, T., 4/09/2017, In : Molecular Neurodegeneration. 12, 63, 11 p., 63.

    Research output: Contribution to journalJournal article

  17. Published

    Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

    Kasai, T., Kondo, M., Ishii, R., Tanaka, A., Ataka, S., Shimada, H., Tomiyama, T., Mori, H., Taylor, M. N., Allsop, D., Nakagawa, M., Mizuno, T. & Tokuda, T., 10/04/2017, In : PLoS ONE. 12, 4

    Research output: Contribution to journalJournal article

  18. Published

    Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

    Castelletto, V., Ryumin, P., Cramer, R., Hamley, I., Taylor, M. N., Allsop, D., Reza, M., Ruokolainen, J., Arnold, T., Hermida-Merino, D., Garcia, C. I., Leal, M. C. & Castaño, E., 8/03/2017, In : Scientific Reports. 7, 12 p., 43637.

    Research output: Contribution to journalJournal article

  19. Published

    ß-Hairpin mimics containing a piperidine-pyrrolidine scaffold modulate the ß-amyloid aggregation process preserving the monomer species

    Pellegrino, S., Tonali, N., Erba, E., Kaffy, J., Taverna, M., Contini, A., Taylor, M. N., Allsop, D., Gelmi, M. L. & Ongeri, S., 1/02/2017, In : Chemical Science. 8, 2, p. 1295-1302 8 p.

    Research output: Contribution to journalJournal article

  20. Published

    Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer’s Aβ peptide

    Gregori, M., Taylor, M. N., Salvati, E., Re, F., Mancini, S., Balducci, C., Forloni, G., Zambelli, V., Sesana, S., Michael, M., Michail, C., Kolosov, O. V., Tinker-Mill, C. L., Sherer, M., Harris, S., Fullwood, N. J., Masserini, M. & Allsop, D., 02/2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 2, p. 723-732 10 p.

    Research output: Contribution to journalJournal article

  21. 2016
  22. Published

    Development and automation of a novel [18F]Fprosthetic group, 2-[18F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

    Morris, O., Gregory, J., Kadirvel, M., Henderson, F., Blykers, A., McMahon, A., Taylor, M. N., Allsop, D., Allan, S., Grigg, J., Boutin, H. & Prenant, C., 10/2016, In : Applied Radiation and Isotopes. 116, p. 120-127 8 p.

    Research output: Contribution to journalJournal article

  23. Published

    Magnetite pollution nanoparticles in the human brain

    Maher, B. A., Ahmed, I., Karloukovski, V. V., MacLaren, D., Foulds, P., Allsop, D., Mann, D., Torres-Jardon, R. & Calderon-Garciduenas, L., 27/09/2016, In : Proceedings of the National Academy of Sciences. 113, 39, p. 10797-10801 5 p.

    Research output: Contribution to journalJournal article

  24. Published

    Effects of different isoforms of apoE on aggregation of the α- synuclein protein implicated in Parkinson's disease

    Nouri Emamzadeh, F., Aojula, H., McHugh, P. & Allsop, D., 8/04/2016, In : Neuroscience Letters. 618, p. 146-151 6 p.

    Research output: Contribution to journalJournal article

  25. Published

    Designed glycopeptidomimetics disrupt protein−protein interactions mediating amyloid β‑peptide aggregation and restore neuroblastoma cell viability

    Kaffy, J., Brinet, D., Soulier, J-L., Tonali, N., Fera, K. F., Iacone, Y., Hoffmann, A. R. F., Khemtemourian, L., Crousse, B., Taylor, M. N., Allsop, D., Taverna, M., Lequin, O. & Ongeri, S., 10/03/2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2025-2040 16 p.

    Research output: Contribution to journalJournal article

  26. 2015
  27. Published

    A preliminary electron microscopic investigation into the interaction between Aβ1-42 peptide and a novel nanoliposome- coupled retro-inverso peptide inhibitor, developed as a potential treatment for Alzheimer's disease

    Sherer, M., Fullwood, N. J., Taylor, M. & Allsop, D., 1/10/2015, In : Journal of Physics: Conference Series. 644, 1, 4 p., 012040.

    Research output: Contribution to journalJournal article

  28. 2014
  29. Published

    Nanomechanical and nanothermal mapping of initial stages of amyloid fibres formation

    Kolosov, O., Tovee, P., Tinker-Mill, C. & Allsop, D., 15/09/2014, p. 29. 1 p.

    Research output: Contribution to conference - Without ISBN/ISSN Abstract

  30. Published

    Amyloid β-peptide and Alzheimer's disease

    Allsop, D. & Mayes, J., 18/08/2014, In : Essays in Biochemistry. 56, p. 99-110 12 p., 7.

    Research output: Contribution to journalLiterature review

  31. Published

    Amyloid-β fibrils in Alzheimer's Disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species

    Mayes, J., Tinker-Mill, C., Kolosov, O., Zhang, H., Tabner, B. & Allsop, D., 25/04/2014, In : Journal of Biological Chemistry. 289, p. 12052-12062 11 p.

    Research output: Contribution to journalJournal article

  32. Published

    Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation

    Tinker-Mill, C., Mayes, J., Allsop, D. & Kolosov, O., 2014, In : Scientific Reports. 4, 7 p., 4004.

    Research output: Contribution to journalJournal article

  33. 2013
  34. Published

    Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples

    Kasai, T., Tokuda, T., Taylor, M., Kondo, M., Mann, D. M. A., Foulds, P., Nakagawa, M. & Allsop, D., 13/09/2013, In : Neuroscience Letters. 551, p. 17-22 6 p.

    Research output: Contribution to journalJournal article

  35. Published

    A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson’s disease

    Foulds, P., Diggle, P., Mitchell, J. D., Parker, A., Hasegawa, M., Masuda-Suzukake, M., Mann, D. M. A. & Allsop, D., 29/08/2013, In : Scientific Reports. 3, 6 p., 2540.

    Research output: Contribution to journalJournal article

  36. Published

    A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's Disease

    Parthsarathy, V., McClean, P. L., Hölscher, C., Taylor, M., Tinker, C., Jones, G., Kolosov, O., Salvati, E., Gregori, M., Masserini, M. & Allsop, D., 2013, In : PLoS ONE. 8, 1, 11 p., e54769.

    Research output: Contribution to journalJournal article

  37. Published

    A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative diseases

    Tabner, B., Moore, S., Mayes, J. & Allsop, D., 2013, Brain diseases and metalloproteins. Brown, D. R. (ed.). Boca Raton, Fla.: Pan Stanford, p. 11-32 22 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  38. 2012
  39. Published

    Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aß oligomers

    Kasai, T., Tokuda, T., Taylor, M., Nakagawa, M. & Allsop, D., 8/06/2012, In : Biochemical and Biophysical Research Communications. 422, 3, p. 375-380 6 p.

    Research output: Contribution to journalJournal article

  40. Published

    Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

    Foulds, P., Yokota, O., Thurston, A., Davidson, Y., Ahmed, Z., Holton, J., Thompson, J. C., Akiyama, H., Arai, T., Hasegawa, M., Gerhard, A., Allsop, D. & Mann, D. M. A., 01/2012, In : Neurobiology of Disease. 45, 1, p. 188-195 8 p.

    Research output: Contribution to journalJournal article

  41. Published

    Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres

    Grishin, I., Tinker, C., Allsop, D., Robson, A. & Kolosov, O., 2012, NSTI-Nanotech 2012. Santa Clara, USA: CRC PRESS-TAYLOR & FRANCIS GROUP, Vol. 1. p. 110-113 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  42. Published

    Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial)

    Foulds, P., Mann, D. & Allsop, D., 2012, In : Expert Review of Molecular Diagnostics. 12, 2, p. 115-117 3 p.

    Research output: Contribution to journalEditorial

  43. 2011
  44. Published

    TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome: association with age, hippocampal sclerosis and clinical phenotype

    Davidson, Y. S., Raby, S., Foulds, P., Robinson, A., Thompson, J. C., Sikkink, S., Yusuf, I., Amin, H., Duplessis, D., Troakes, C., Al-Sarraj, S., Sloan, C., Esiri, M. M., Prasher, V. P., Allsop, D., Neary, D., Pickering-Brown, S. M., Snowden, J. S. & Mann, D. M. A., 12/2011, In : Acta Neuropathologica. 122, 6, p. 703-713 11 p.

    Research output: Contribution to journalJournal article

  45. Published

    Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide

    Taylor, M., Moore, S., Mourtas, S., Niarakis, A., Re, F., Zona, C., La Ferla, B., Nicotra, F., Masserini, M., Antimisiaris, S. G., Gregori, M. & Allsop, D., 10/2011, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 7, 5, p. 541-550 10 p.

    Research output: Contribution to journalJournal article

  46. Published

    The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

    Masad, A., Tabner, B. J., Mayes, J. & Allsop, D., 15/08/2011, In : Free Radical Biology and Medicine. 51, 4, p. 869-875 7 p.

    Research output: Contribution to journalJournal article

  47. Published

    Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

    Foulds, P., Mitchell, J. D., Parker, A., Turner, R., Green, G., Diggle, P., Hasegawa, M., Taylor, M., Mann, D. & Allsop, D., 2011, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25, 12, p. 4127-4137 11 p.

    Research output: Contribution to journalJournal article

  48. 2010
  49. Published

    Hypothesis: soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease

    Tabner, B. J., Mayes, J. & Allsop, D., 8/10/2010, In : International Journal of Alzheimer's Disease. 2011, 6 p., 546380.

    Research output: Contribution to journalJournal article

  50. Published

    Parkinson disease: progress towards a molecular biomarker for Parkinson disease

    Foulds, P., Mann, D. M. A., Mitchell, J. D. & Allsop, D., 07/2010, In : Nature Reviews Neurology. 6, 7, p. 359-361 3 p.

    Research output: Contribution to journalJournal article

  51. Published

    Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimer's disease

    Taylor, M., Moore, S., Mayes, J., Parkin, E., Beeg, M., Canovi, M., Gobbi, M., Mann, D. M. A. & Allsop, D., 2010, In : Biochemistry. 49, 15, p. 3261-3272 12 p.

    Research output: Contribution to journalJournal article

  52. Published

    High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

    Fukumoto, H., Tokuda, T., Kasai, T., Ishigami, N., Hidaka, H., Kondo, M., Allsop, D. & Nakagawa, M., 2010, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24, 8, p. 2716-2726 11 p.

    Research output: Contribution to journalJournal article

  53. 2009
  54. Published

    Galantamine inhibits β-amyloid aggregation and cytotoxicity

    Matharu, B., Gibson, G., Parsons, R., Huckerby, T. N., Moore, S. A., Cooper, L. J., Millichamp, R., Allsop, D. & Austen, B., 15/05/2009, In : Journal of the Neurological Sciences. 280, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalJournal article

  55. Published

    Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies

    Paleologou, K. E., Kragh, C. L., Mann, D. M. A., Salem, S. A., Al-Shami, R., Allsop, D., Hassan, A. H., Jensen, P. H. & El-Agnaf, O. M. A., 2009, In : Brain. 132, 4, p. 1093-1101 9 p.

    Research output: Contribution to journalJournal article

  56. Published

    Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

    Kasai, T., Tokuda, T., Ishigami, N., Sasayama, H., Foulds, P., Mitchell, D. J., Mann, D. M. A., Allsop, D. & Nakagawa, M., 2009, In : Acta Neuropathologica. 117, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal article

  57. Published

    Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

    Foulds, P., Davidson, Y., Mishra, M., Hobson, D. J., Humphreys, K. M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E. H., Benson, F. E., Allsop, D. & Mann, D. M. A., 2009, In : Acta Neuropathologica. 118, 5, p. 647-658 12 p.

    Research output: Contribution to journalJournal article

  58. 2008
  59. Published

    Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide

    Austen, B. M., Paleologou, K. E., Ali, S. A. E., Qureshi, M. M., Allsop, D. & El-Agnaf, O. M. A., 2008, In : Biochemistry. 47, 7, p. 1984-1992 9 p.

    Research output: Contribution to journalJournal article

  60. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In : Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to journalJournal article

  61. Published

    TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration

    Foulds, P., McAuley, E., Gibbons, L., Davidson, Y., Pickering-Brown, S. M., Neary, D., Snowden, J. S., Allsop, D. & Mann, D. M. A., 2008, In : Acta Neuropathologica. 116, 2, p. 141-146 6 p.

    Research output: Contribution to journalJournal article

  62. 2007
  63. Published

    An investigation into the lipid-binding properties of α-, β- and γ-synucleins in human brain and cerebrospinal fluid

    Salem, S. A., Allsop, D., Mann, D. M. A., Tokuda, T. & El-Agnaf, O. M. A., 19/09/2007, In : Experimental Brain Research. 1170, p. 103-111 9 p.

    Research output: Contribution to journalJournal article

  64. Published

    Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

    Masad, A., Hayes, L., Tabner, B., Turnbull, S., Cooper, L., Fullwood, N. J., German, M., Kametani, F., El-Agnaf, O. M. A. & Allsop, D., 2007, In : FEBS Letters. 581, 18, p. 3489-3493 5 p.

    Research output: Contribution to journalJournal article

  65. 2006
  66. Published

    Plasma amyloid-β concentrations in Alzheimer's disease : an alternative hypothesis.

    Fullwood, N. J., Hayashi, Y. & Allsop, D., 12/2006, In : Lancet Neurology. 5, 12, p. 1000-1001 2 p.

    Research output: Contribution to journalJournal article

  67. Published

    Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease.

    Tokuda, T., Salem, S. A., Allsop, D., Mizuno, T., Nakagawa, M., Qureshi, M. M., Locascio, J. J., Schlossmacher, M. G. & El-Agnaf, O., 13/10/2006, In : Biochemical and Biophysical Research Communications. 349, 1, p. 162-166 5 p.

    Research output: Contribution to journalJournal article

  68. Published

    Donepezil for severe Alzheimer's disease.

    Allsop, D., Martin, F., Moore, S. & Fullwood, N. J., 29/07/2006, In : Lancet. 368, 9533, p. 361-362 2 p.

    Research output: Contribution to journalJournal article

  69. Published

    A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein.

    Tabner, B. J., Turnbull, S., King, J., Benson, F. E., El-Agnaf, O. M. A. & Allsop, D., 07/2006, In : Free Radical Research. 40, 7, p. 731-739 9 p.

    Research output: Contribution to journalJournal article

  70. Published

    Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Curran, M. D., Gibson, M. J., Court, J. A., Schlossmacher, M. G. & Allsop, D., 2006, In : FASEB Journal. 20, 3, p. 419-425 7 p.

    Research output: Contribution to journalJournal article

  71. 2005
  72. Published

    Protein aggregation, metals and oxidative stress in neurodegenerative diseases.

    Tabner, B. J., El-Agnaf, O. M. A., German, M. J., Fullwood, N. J. & Allsop, D., 11/2005, In : Biochemical Society Transactions. 33, 5, p. 1082-1086 5 p.

    Research output: Contribution to journalJournal article

  73. Published

    Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia.

    Tabner, B. J., El-Agnaf, O. M. A., Turnbull, S., German, M. J., Paleologou, K. E., Hayashi, Y., Cooper, L. J., Fullwood, N. & Allsop, D., 28/10/2005, In : Journal of Biological Chemistry. 280, 43, p. 35789-35792 4 p.

    Research output: Contribution to journalJournal article

  74. Published

    The production of hydrogen peroxide during early-stage protein aggregation: a common pathological mechanism in different neurodegenerative diseases?

    Tabner, B., Turnbull, S., Fullwood, N. J., German, M. & Allsop, D., 08/2005, In : Biochemical Society Transactions. 33, 4, p. 548-550 3 p.

    Research output: Contribution to journalJournal article

  75. 2004
  76. Published

    A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.

    El-Agnaf, O. M. A., Paleologou, K. E., Greer, B., Abogrein, A. M., King, J., Salem, S. A., Fullwood, N. J., Benson, F. E., Hewitt, R., Ford, K. J., Martin, F., Harriott, P., Cookson, M. R. & Allsop, D., 08/2004, In : FASEB Journal. 18, 11, p. 1315-1317 3 p.

    Research output: Contribution to journalJournal article

  77. Published

    Both the D-(+) and L-(-) enantiomers of nicotine inhibit Aβ aggregation and cytotoxicity.

    Moore, S. A., Huckerby, T. N., Gibson, G. L., Fullwood, N. J., Turnbull, I., Tabner, B. J., El-Agnaf, O. M. A. & Allsop, D., 01/2004, In : Biochemistry. 43, 3, p. 819-826 8 p.

    Research output: Contribution to journalJournal article

  78. Published

    Induction of cellular oxidative stress by the β-amyloid peptide involved in Alzheimer's disease.

    Gibson, G. L., Allsop, D. & Austen, B. M., 2004, In : Protein and Peptide Letters. 11, 3, p. 257-270 14 p.

    Research output: Contribution to journalJournal article

  79. Published

    α-Synuclein and the pathogenesis of Parkinson’s disease.

    Martin, F., Allsop, D., Williamson, S. J. M., Paleologou, K. E. & El-Agnaf, O. M. A., 2004, In : Protein and Peptide Letters. 11, 3, p. 229-237 9 p.

    Research output: Contribution to journalJournal article

  80. 2003
  81. Published

    Fe(II)-induced DNA damage in α-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay.

    Martin, F., Williamson, S. J. M., Paleologou, K. E., Hewitt, R., El-Agnaf, O. M. A. & Allsop, D., 11/2003, In : Journal of Neurochemistry. 87, 3, p. 620-630 11 p.

    Research output: Contribution to journalJournal article

  82. Published

    α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma.

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Cooper, L. J., Fullwood, N. J., Gibson, M. J., Curran, M. D., Court, J. A., Mann, D. M. A., Ikeda, S-I., Cookson, M. R., Hardy, J. & Allsop, D., 10/2003, In : FASEB Journal. 17, 13, p. 1945-1947 3 p.

    Research output: Contribution to journalJournal article

  83. Published

    Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 15/09/2003, In : NeuroReport. 14, 13, p. 1743-1745 3 p.

    Research output: Contribution to journalJournal article

  84. Published

    Soluble oligomers for the diagnosis of neurodegenerative diseases.

    El-Agnaf, O. M. A., Walsh, D. M. & Allsop, D., 08/2003, In : Lancet Neurology. 2, 8, p. 461-462 2 p.

    Research output: Contribution to journalJournal article

  85. Published

    Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 1/07/2003, In : Biochemistry. 42, 25, p. 7675-7681 7 p.

    Research output: Contribution to journalJournal article

  86. Published

    Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 23/01/2003, In : Neuroscience Letters. 336, 3, p. 159-162 4 p.

    Research output: Contribution to journalJournal article

  87. Published

    Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2003, In : Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents. 3, 4, p. 299-308 10 p.

    Research output: Contribution to journalJournal article

  88. 2002
  89. Published

    Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 1/06/2002, In : Free Radical Biology and Medicine. 32, 11, p. 1076-1083 8 p.

    Research output: Contribution to journalJournal article

  90. Published

    Inherited frontotemporal dementia in 9 British families associated with intronic mutations in the tau gene.

    Pickering-Brown, S. M., Richardson, A. M. T., Snowden, J. S., McDonagh, A., Burns, A., Braudie, W., Baker, M., Yen, S-H., Hardy, J., Hutton, M., Davies, Y., Allsop, D., Craufurd, D., Neary, D. & Mann, D. M. A., 04/2002, In : Brain. 125, 4, p. 732-751 20 p.

    Research output: Contribution to journalJournal article

  91. 2001
  92. Published

    Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

    Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In : Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

    Research output: Contribution to journalJournal article

  93. Published

    New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps.

    Turnbull, S., Tabner, B. J., El-Agnaf, O. M. A., Twyman, L. J. & Allsop, D., 15/05/2001, In : Free Radical Biology and Medicine. 30, 10, p. 1154-1162 9 p.

    Research output: Contribution to journalJournal article

  94. Published

    α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro.

    Turnbull, S., Tabner, B. J., Moore, S., Davies, Y., El-Agnaf, O. M. A. & Allsop, D., 15/05/2001, In : Free Radical Biology and Medicine. 30, 10, p. 1163-1170 8 p.

    Research output: Contribution to journalJournal article

  95. Published

    3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide.

    Allsop, D., Gibson, G., Martin, I. K., Moore, S., Turnbull, S. & Twyman, L. J., 01/2001, In : Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 255-257 3 p.

    Research output: Contribution to journalJournal article

  96. Published

    Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2001, In : Current Topics in Medicinal Chemistry. 1, p. 483-493 11 p.

    Research output: Contribution to journalJournal article

  97. Published

    The biology and molecular neuropathology of β-amyloid protein.

    Howlett, D. R., Allsop, D. & Karran, E. H., 2001, Neurobiology of Alzheimer's disease . Dawbarn, D. & Allen, S. J. (eds.). 2nd ed. ed. Oxford: Oxford University Press, p. 75-102 28 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  98. 2000
  99. Published

    Pick's disease is associated with mutations in the tau gene.

    Pickering-Brown, S., Baker, M., Yen, S-H., Liu, W-K., Hasegawa, M., Cairns, N., Lantos, P. L., Rossor, M., Iwatsubo, T., Davies, Y., Allsop, D., Furlong, R., Owen, F., Hardy, J., David Mann, D. & Hutton, M., 12/2000, In : Annals of Neurology. 48, 6, p. 589-867 279 p.

    Research output: Contribution to journalJournal article

  100. Published

    Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells

    Gardner, R. C., Assinder, S. J., Christie, G., Mason, G. G. F., Markwell, R., Wadsworth, H., McLaughlin, M., King, R., Chabot-Fletcher, M. C., Breton, J., Allsop, D. & Rivett, A. J., 2000, In : Biochemical Journal. 346, p. 447-454 8 p.

    Research output: Contribution to journalJournal article

  101. Published

    Introduction to Alzheimer's disease.

    Allsop, D., 2000, Alzheimer's disease : methods and protocols. Hooper, N. (ed.). Totawa, New Jersey: Humana Press, p. 1-21 21 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  102. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In : Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to journalLiterature review

  103. 1999
  104. Published

    A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

    Twyman, L. J. & Allsop, D., 12/1999, In : Tetrahedron Letters. 40, 52, p. 9383-9384 2 p.

    Research output: Contribution to journalJournal article

  105. Published

    Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

    Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A. & 4 others, Gardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In : Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

    Research output: Contribution to journalJournal article

  106. Published

    Biological activity associated with a high molecular weight form of β-amyloid.

    Howlett, D. R., Ward, R. V., Bresciani, L., Jennings, K. H., Christie, G., Allsop, D., Gray, C. W. & Karran, E. H., 1999, In : Alzheimer's Reports. 2, p. 171-177 7 p.

    Research output: Contribution to journalJournal article

  107. Published

    Characterization of an α-secretase candidate from human brain using a new western blot assay

    Evin, G., Reed, G., Tanner, J. E., Li, Q. X., Culvenor, J. G., Fuller, S. J., Wadsworth, H., Allsop, D., Ward, R. V., Karran, E. H., Gray, C. W., Hartmann, T., Lichtenthaler, S. F., Weidemann, A., Beyreuther, K. & Masters, C. L., 1999, Alzheimer's disease and related disorders. Iqbal, K., Swaab, D. F., Winblad, B. & Wisniewski, H. M. (eds.). Wiley, p. 411-418 8 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  108. 1998
  109. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In : Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to journalJournal article

  110. Published

    Presenilins: in search of functionality

    Karran, E. H., Allsop, D., Christie, G., Davis, J., Gray, C., Mansfield, F. & Ward, R. V., 08/1998, In : Biochemical Society Transactions. 26, 3, p. 491-496 6 p.

    Research output: Contribution to journalJournal article

  111. 1997
  112. Published

    Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

    Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In : Nature Medicine. 3, 9, p. 1016-1020 5 p.

    Research output: Contribution to journalJournal article

  113. Published

    Studies on inhibition of β-amyloid formation in APP-751-transfected IMR-32 cells, and SPA4CT-transfected SHSY5Y cells

    Allsop, D., Christie, G., Gray, C., Holmes, S., Markwell, R., Owen, D., Smith, L., Wadsworth, H., Ward, R. V., Hartmann, T., Lichtenthaler, S. F., Evin, G., Fuller, S., Tanner, J., Masters, C. L., Beyreuther, K. & Roberts, G. W., 1997, Alzheimer's disease: biology, diagnosis and therapeutics. Iqbal, K., Winblad, B., Nishimura, T., Takeda, M. & Wisniewski, H. M. (eds.). New York: Wiley, p. 717-727 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  114. 1996
  115. Published

    Effect of aluminium on expression and processing of amyloid precursor protein

    Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., Rima, B. K., Morris, C., Candy, J. M. & Edwardson, J. A., 15/11/1996, In : Journal of Neuroscience Research. 46, 4, p. 395-403 9 p.

    Research output: Contribution to journalJournal article

  116. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In : Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to journalJournal article

  117. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Howlett, D. R., James, S., Allsop, D. & Roberts, G. W., 1996, Neurobiology of Alzheimer's disease. Dawbarn, D. & Allen, S. J. (eds.). Oxford: BIOS Scientific Publishers, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  118. 1995
  119. Published

    The immunoreactive profile at the N-terminal region of Aβ1-39/40 but not Aβ1-42 changes with transition from monomer/dimer to further peptide aggregates

    Kametani, F., Tanaka, K., Tokuda, T. & Allsop, D., 12/12/1995, In : Brain Research. 703, 1-2, p. 237-241 5 p.

    Research output: Contribution to journalJournal article

  120. 1994
  121. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In : Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to journalJournal article

  122. Published

    Gerstmann-Sträussler-Scheinker disease showing β-protein type cerebellar and cerebral amyloid angiopathy

    Ikeda, S. I., Yanagisawa, N., Allsop, D. & Glenner, G. G., 09/1994, In : Acta Neuropathologica. 88, 3, p. 262-266 5 p.

    Research output: Contribution to journalJournal article

  123. Published

    Aggregation of Alzheimer's peptides

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In : Biochemical Society Transactions. 22, 1, p. 16S 1 p.

    Research output: Contribution to journalJournal article

  124. Published

    Amyloidosis in Alzheimer's disease

    Allsop, D. & Williams, C. H., 1994, In : Biochemical Society Transactions. 22, 1, p. 171-175 5 p.

    Research output: Contribution to journalJournal article

  125. Published

    An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

    Walsh, D. M., Williams, C. H., Kennedy, H. E. & Allsop, D., 1994, In : Biochemical Society Transactions. 22, 1, p. 14S 1 p.

    Research output: Contribution to journalJournal article

  126. Published

    Gelatinase A not α-secretase?

    Walsh, D. M., Williams, C. H., Kennedy, H. E., Allsop, D. & Murphy, G., 1994, In : Nature. 367, 6458, p. 27-28 2 p.

    Research output: Contribution to journalJournal article

Previous 1 2 Next

Back to top