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Professor David Allsop

Professor

  1. Published

    Donepezil for severe Alzheimer's disease.

    Allsop, D., Martin, F., Moore, S. & Fullwood, N. J., 29/07/2006, In : Lancet. 368, 9533, p. 361-362 2 p.

    Research output: Contribution to journalJournal article

  2. Published

    3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide.

    Allsop, D., Gibson, G., Martin, I. K., Moore, S., Turnbull, S. & Twyman, L. J., 01/2001, In : Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 255-257 3 p.

    Research output: Contribution to journalJournal article

  3. Published

    Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

    Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In : Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

    Research output: Contribution to journalJournal article

  4. Published

    Introduction to Alzheimer's disease.

    Allsop, D., 2000, Alzheimer's disease : methods and protocols. Hooper, N. (ed.). Totawa, New Jersey: Humana Press, p. 1-21 21 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  5. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In : Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to journalJournal article

  6. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In : Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to journalJournal article

  7. Published

    Amyloidosis in Alzheimer's disease

    Allsop, D. & Williams, C. H., 1994, In : Biochemical Society Transactions. 22, 1, p. 171-175 5 p.

    Research output: Contribution to journalJournal article

  8. Published

    Alzheimer amyloid β/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 14/06/1991, In : Brain Research. 551, 1-2, p. 1-9 9 p.

    Research output: Contribution to journalJournal article

  9. Published

    Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid β-protein of Alzheimer's disease

    Allsop, D., Haga, S., Bruton, C., Ishii, T. & Roberts, G. W., 02/1990, In : American Journal of Pathology. 136, 2, p. 255-260 6 p.

    Research output: Contribution to journalJournal article

  10. Published

    The nomenclature of the cerebral amyloid fibril protein in Alzheimer's disease

    Allsop, D., 01/1990, In : Neurobiology of Aging. 11, 1, p. 63-64 2 p.

    Research output: Contribution to journalJournal article

  11. Published

    A possible unified nomenclature for Alzheimer amyloid protein, precursors and gene

    Allsop, D., 01/1990, In : Neurobiology of Aging. 11, 1, p. 69 1 p.

    Research output: Contribution to journalJournal article

  12. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

    Allsop, D., Haga, S. I., Haga, C., Ikeda, S. I., Mann, D. M. & Ishii, T., 12/1990, In : Neuropathology and Applied Neurobiology. 15, 6, p. 531-542 12 p.

    Research output: Contribution to journalJournal article

  13. Published

    Evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. & Glenner, G. G., 1989, In : Progress in Clinical and Biological Research. 317, p. 893-902 10 p.

    Research output: Contribution to journalJournal article

  14. Published

    Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein

    Allsop, D., Ikeda, S., Bruce, M. & Glenner, G. G., 5/10/1988, In : Neuroscience Letters. 92, 2, p. 234-239 6 p.

    Research output: Contribution to journalJournal article

  15. Published

    Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer disease

    Allsop, D., Wong, C. W., Ikeda, S., Landon, M., Kidd, M. & Glenner, G. G., 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 8, p. 2790-2794 5 p.

    Research output: Contribution to journalJournal article

  16. Published

    Isolated senile plaque cores in Alzheimer's disease and Down's syndrome show differences in morphology

    Allsop, D., Kidd, M., Landon, M. & Tomlinson, A., 1986, In : Journal of Neurology, Neurosurgery and Psychiatry. 49, 8, p. 886-892 7 p.

    Research output: Contribution to journalJournal article

  17. Published

    Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

    Allsop, D., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Gardner, A., 1986, In : Neuroscience Letters. 68, 2, p. 252-6 5 p.

    Research output: Contribution to journalJournal article

  18. Published

    The isolation and amino acid composition of senile plaque core protein

    Allsop, D., Landon, M. & Kidd, M., 1983, In : Experimental Brain Research. 259, 2, p. 348-52 5 p.

    Research output: Contribution to journalJournal article

  19. Published

    The effect of a high non-permissive temperature on chloroplast development in barley

    Allsop, D., Atkinson, Y. E. & Bradbeer, J. W., 1981, Photosynthesis V: chloroplast development. Akoyunoglou, G. (ed.). Philadelphia: Balaban International Science Services, p. 787-795 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  20. Published

    Biochemistry of cerebral amyloid in Alzheimer’s disease, the unconventional slow virus diseases, and Icelandic cerebrovascular amyloidosis

    Allsop, D., 1986, Amyloidosis. Marrink, J. & van Rijswijk, M. H. (eds.). Dordrecht: Martinus Nijhoff Publishers/ Brill Academic, p. 243-253 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  21. Published

    Antibody staining of cerebral amyloid in Alzheimer’s disease, Down’s syndrome, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome

    Allsop, D., Roberts, G. W., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Crowe, T. J., 1987, Advancing Frontiers in Alzheimer’s Disease Research. Glenner, G. G. & Wurtman, J. (eds.). Austin: University of Texas Press, p. 137-153 17 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  22. Published

    Evidence for the derivation of a peptide ligand from the amyloid β protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. I. & Glenner, G. G., 1989, Alzheimer's disease and related disorders: proceedings of the First International Conference on Alzheimer's Disease and Related Disorders, held in Las Vegas, Nevada, September 5-9, 1988. Iqbal, K., Wisniewski, H. M. & Winblad, B. (eds.). New York: Alan R. Liss, p. 893-902 10 p. (Progress in clinical and biological research; vol. 317).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  23. Published

    Evidence for a neuronal origin of senile plaques in Down's syndrome brains

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Basic and therapeutic aspects of Alzheimer's and Parkinson's diseases. Nagatsu, T. (ed.). New York: Plenum Press, Vol. 1. p. 83-86 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  24. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons: evidence for a neuronal origin of senile plaque amyloid

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Molecular biology and genetics of Alzheimer disease. Miyatake, T., Selkoe, D. J. & Ihara, Y. (eds.). Amsterdam: Elsevier, p. 95-104 10 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  25. Published

    Studies on the binding and proteolytic cleavage of an Alzheimer amyloid synthetic peptide

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Frontiers of Alzheimer research. Ishii, T., Allsop, D. & Selkoe, D. J. (eds.). Amsterdam: Elsevier, p. 171-183 13 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  26. Published

    High affinity amyloid peptide β/A4 binding sites and a putative "APP secretase" in rat brain

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Proceedings of the XIth International Congress of Neuropathology: The Japanese Society of Neuropathology. Sasaki, Japan, p. 119-127 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  27. Published

    Secretory derivatives of Alzheimer amyloid precursor protein in cerebrospinal fluid and brain: only Kunitz-containing forms show amyloid immunoreactivity

    Allsop, D., Kennedy, H. E. & Kametani, F., 1993, Alzheimer's disease: advances in clinical and basic research. Corain, B., Iqbal, K., Nicolini, M., Winblad, B., Wisniewski, H. M. & Zatta, P. (eds.). Chichester: Wiley, p. 421-429 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  28. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Allsop, D., Clements, A., Kennedy, H. E., Walsh, D. M. & Williams, C. H., 1994, Amyloid precursor protein in development, ageing and Alzheimer's disease. Berlin: Springer Verlag, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  29. Published

    Studies on inhibition of β-amyloid formation in APP-751-transfected IMR-32 cells, and SPA4CT-transfected SHSY5Y cells

    Allsop, D., Christie, G., Gray, C., Holmes, S., Markwell, R., Owen, D., Smith, L., Wadsworth, H., Ward, R. V., Hartmann, T., Lichtenthaler, S. F., Evin, G., Fuller, S., Tanner, J., Masters, C. L., Beyreuther, K. & Roberts, G. W., 1997, Alzheimer's disease: biology, diagnosis and therapeutics. Iqbal, K., Winblad, B., Nishimura, T., Takeda, M. & Wisniewski, H. M. (eds.). New York: Wiley, p. 717-727 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  30. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In : Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to journalLiterature review

  31. Published

    Amyloid β-peptide and Alzheimer's disease

    Allsop, D. & Mayes, J., 18/08/2014, In : Essays in Biochemistry. 56, p. 99-110 12 p., 7.

    Research output: Contribution to journalLiterature review

  32. Published

    A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation

    Allsop, D., Taylor, M. N., Fullwood, N. J., Michael, M., Aggidis, A., Vincent, S. & Dale, M., 1/11/2017, In : Journal of Prevention of Alzheimer's Disease. 4, 4, p. 385-386 2 p.

    Research output: Contribution to journalMeeting abstract

  33. Published

    Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease

    Allsop, D., Aggidis, A., Fullwood, N. J., Taylor, M. N., Foulds, P., Vincent, S. & Dale, M., 2018, In : Journal of Prevention of Alzheimer's Disease. 5, Suppl 1, p. S15-S16 2 p.

    Research output: Contribution to journalMeeting abstract

  34. Published

    Chloroplast development in normal and mutant lines of barley

    Atkinson, Y. E., Allsop, D. & Bradbeer, J. W., 1981, Photosynthesis V: chloroplast development. Akoyunoglou, G. (ed.). Philadelphia: Balaban International Science Services, p. 797-808 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  35. Published

    Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide

    Austen, B. M., Paleologou, K. E., Ali, S. A. E., Qureshi, M. M., Allsop, D. & El-Agnaf, O. M. A., 2008, In : Biochemistry. 47, 7, p. 1984-1992 9 p.

    Research output: Contribution to journalJournal article

  36. Published

    Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

    Castelletto, V., Ryumin, P., Cramer, R., Hamley, I., Taylor, M. N., Allsop, D., Reza, M., Ruokolainen, J., Arnold, T., Hermida-Merino, D., Garcia, C. I., Leal, M. C. & Castaño, E., 8/03/2017, In : Scientific Reports. 7, 12 p., 43637.

    Research output: Contribution to journalJournal article

  37. Published

    Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

    Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A. & 4 others, Gardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In : Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

    Research output: Contribution to journalJournal article

  38. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In : Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to journalJournal article

  39. Published

    Aggregation of Alzheimer's peptides

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In : Biochemical Society Transactions. 22, 1, p. 16S 1 p.

    Research output: Contribution to journalJournal article

  40. Published

    Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In : Neuroscience Letters. 161, 1, p. 17-20 4 p.

    Research output: Contribution to journalJournal article

  41. Published

    TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome: association with age, hippocampal sclerosis and clinical phenotype

    Davidson, Y. S., Raby, S., Foulds, P., Robinson, A., Thompson, J. C., Sikkink, S., Yusuf, I., Amin, H., Duplessis, D., Troakes, C., Al-Sarraj, S., Sloan, C., Esiri, M. M., Prasher, V. P., Allsop, D., Neary, D., Pickering-Brown, S. M., Snowden, J. S. & Mann, D. M. A., 12/2011, In : Acta Neuropathologica. 122, 6, p. 703-713 11 p.

    Research output: Contribution to journalJournal article

  42. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In : Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to journalJournal article

  43. Published

    Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Curran, M. D., Gibson, M. J., Court, J. A., Schlossmacher, M. G. & Allsop, D., 2006, In : FASEB Journal. 20, 3, p. 419-425 7 p.

    Research output: Contribution to journalJournal article

  44. Published

    A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.

    El-Agnaf, O. M. A., Paleologou, K. E., Greer, B., Abogrein, A. M., King, J., Salem, S. A., Fullwood, N. J., Benson, F. E., Hewitt, R., Ford, K. J., Martin, F., Harriott, P., Cookson, M. R. & Allsop, D., 08/2004, In : FASEB Journal. 18, 11, p. 1315-1317 3 p.

    Research output: Contribution to journalJournal article

  45. Published

    α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma.

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Cooper, L. J., Fullwood, N. J., Gibson, M. J., Curran, M. D., Court, J. A., Mann, D. M. A., Ikeda, S-I., Cookson, M. R., Hardy, J. & Allsop, D., 10/2003, In : FASEB Journal. 17, 13, p. 1945-1947 3 p.

    Research output: Contribution to journalJournal article

  46. Published

    Soluble oligomers for the diagnosis of neurodegenerative diseases.

    El-Agnaf, O. M. A., Walsh, D. M. & Allsop, D., 08/2003, In : Lancet Neurology. 2, 8, p. 461-462 2 p.

    Research output: Contribution to journalJournal article

  47. Published

    Characterization of an α-secretase candidate from human brain using a new western blot assay

    Evin, G., Reed, G., Tanner, J. E., Li, Q. X., Culvenor, J. G., Fuller, S. J., Wadsworth, H., Allsop, D., Ward, R. V., Karran, E. H., Gray, C. W., Hartmann, T., Lichtenthaler, S. F., Weidemann, A., Beyreuther, K. & Masters, C. L., 1999, Alzheimer's disease and related disorders. Iqbal, K., Swaab, D. F., Winblad, B. & Wisniewski, H. M. (eds.). Wiley, p. 411-418 8 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  48. Published

    Parkinson disease: progress towards a molecular biomarker for Parkinson disease

    Foulds, P., Mann, D. M. A., Mitchell, J. D. & Allsop, D., 07/2010, In : Nature Reviews Neurology. 6, 7, p. 359-361 3 p.

    Research output: Contribution to journalJournal article

  49. Published

    Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

    Foulds, P., Davidson, Y., Mishra, M., Hobson, D. J., Humphreys, K. M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E. H., Benson, F. E., Allsop, D. & Mann, D. M. A., 2009, In : Acta Neuropathologica. 118, 5, p. 647-658 12 p.

    Research output: Contribution to journalJournal article

  50. Published

    Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

    Foulds, P., Yokota, O., Thurston, A., Davidson, Y., Ahmed, Z., Holton, J., Thompson, J. C., Akiyama, H., Arai, T., Hasegawa, M., Gerhard, A., Allsop, D. & Mann, D. M. A., 01/2012, In : Neurobiology of Disease. 45, 1, p. 188-195 8 p.

    Research output: Contribution to journalJournal article

  51. Published

    TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration

    Foulds, P., McAuley, E., Gibbons, L., Davidson, Y., Pickering-Brown, S. M., Neary, D., Snowden, J. S., Allsop, D. & Mann, D. M. A., 2008, In : Acta Neuropathologica. 116, 2, p. 141-146 6 p.

    Research output: Contribution to journalJournal article

  52. Published

    Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

    Foulds, P., Mitchell, J. D., Parker, A., Turner, R., Green, G., Diggle, P., Hasegawa, M., Taylor, M., Mann, D. & Allsop, D., 2011, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25, 12, p. 4127-4137 11 p.

    Research output: Contribution to journalJournal article

  53. Published

    Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial)

    Foulds, P., Mann, D. & Allsop, D., 2012, In : Expert Review of Molecular Diagnostics. 12, 2, p. 115-117 3 p.

    Research output: Contribution to journalEditorial

  54. Published

    A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson’s disease

    Foulds, P., Diggle, P., Mitchell, J. D., Parker, A., Hasegawa, M., Masuda-Suzukake, M., Mann, D. M. A. & Allsop, D., 29/08/2013, In : Scientific Reports. 3, 6 p., 2540.

    Research output: Contribution to journalJournal article

  55. Published

    A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease

    Foulds, PG., Diggle, P., Mitchell, JD., Parker, A., Hasegawa, M., Masuda-Suzukake, M., Mann, DM. & Allsop, D., 2013, In : Scientific Reports. 3, 6 p., 2540.

    Research output: Contribution to journalJournal article

  56. Published

    High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

    Fukumoto, H., Tokuda, T., Kasai, T., Ishigami, N., Hidaka, H., Kondo, M., Allsop, D. & Nakagawa, M., 2010, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24, 8, p. 2716-2726 11 p.

    Research output: Contribution to journalJournal article

  57. Published

    Plasma amyloid-β concentrations in Alzheimer's disease : an alternative hypothesis.

    Fullwood, N. J., Hayashi, Y. & Allsop, D., 12/2006, In : Lancet Neurology. 5, 12, p. 1000-1001 2 p.

    Research output: Contribution to journalJournal article

  58. Published

    Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells

    Gardner, R. C., Assinder, S. J., Christie, G., Mason, G. G. F., Markwell, R., Wadsworth, H., McLaughlin, M., King, R., Chabot-Fletcher, M. C., Breton, J., Allsop, D. & Rivett, A. J., 2000, In : Biochemical Journal. 346, p. 447-454 8 p.

    Research output: Contribution to journalJournal article

  59. Published

    Quantification of βA4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

    Gentleman, S. M., Williams, B., Royston, M. C., Jagoe, R., Clinton, J., Perry, R. H., Ince, P. G., Allsop, D., Polak, J. M. & Roberts, G. W., 3/08/1992, In : Neuroscience Letters. 142, 1, p. 9-12 4 p.

    Research output: Contribution to journalJournal article

  60. Published

    Quantitative differences in the deposition of βA4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

    Gentleman, S. M., Allsop, D., Bruton, C. J., Jagoe, R., Polak, J. M. & Roberts, G. W., 17/02/1992, In : Neuroscience Letters. 136, 1, p. 27-30 4 p.

    Research output: Contribution to journalJournal article

  61. Published

    β(A4)-amyloid protein and parkinsonian dementia complex of Guam

    Gentleman, S. M., Perl, D., Allsop, D., Clinton, J., Royston, M. C. & Roberts, G. W., 5/01/1991, In : Lancet. 337, 8732, p. 55-56 2 p.

    Research output: Contribution to journalLetter

  62. Published

    A demonstration of the advantages of immunostaining in the quantification of amyloid plaque deposits

    Gentleman, S. M., Bruton, C., Allsop, D., Lewis, S. J., Polak, J. M. & Roberts, G. W., 1989, In : Histochemistry. 92, 4, p. 355-358 4 p.

    Research output: Contribution to journalJournal article

  63. Published

    Induction of cellular oxidative stress by the β-amyloid peptide involved in Alzheimer's disease.

    Gibson, G. L., Allsop, D. & Austen, B. M., 2004, In : Protein and Peptide Letters. 11, 3, p. 257-270 14 p.

    Research output: Contribution to journalJournal article

  64. Published

    Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer’s Aβ peptide

    Gregori, M., Taylor, M. N., Salvati, E., Re, F., Mancini, S., Balducci, C., Forloni, G., Zambelli, V., Sesana, S., Michael, M., Michail, C., Kolosov, O. V., Tinker-Mill, C. L., Sherer, M., Harris, S., Fullwood, N. J., Masserini, M. & Allsop, D., 02/2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 2, p. 723-732 10 p.

    Research output: Contribution to journalJournal article

  65. Published

    Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres

    Grishin, I., Tinker, C., Allsop, D., Robson, A. & Kolosov, O., 2012, NSTI-Nanotech 2012. Santa Clara, USA: CRC PRESS-TAYLOR & FRANCIS GROUP, Vol. 1. p. 110-113 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  66. Published

    Amyloid deposition as the central event in the aetiology of Alzheimer's disease

    Hardy, J. & Allsop, D., 1991, In : Trends in Pharmacological Sciences. 12, 10, p. 383-388 6 p.

    Research output: Contribution to journalJournal article

  67. Published

    Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

    Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In : Nature Medicine. 3, 9, p. 1016-1020 5 p.

    Research output: Contribution to journalJournal article

  68. Published

    The biology and molecular neuropathology of β-amyloid protein.

    Howlett, D. R., Allsop, D. & Karran, E. H., 2001, Neurobiology of Alzheimer's disease . Dawbarn, D. & Allen, S. J. (eds.). 2nd ed. ed. Oxford: Oxford University Press, p. 75-102 28 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  69. Published

    Biological activity associated with a high molecular weight form of β-amyloid.

    Howlett, D. R., Ward, R. V., Bresciani, L., Jennings, K. H., Christie, G., Allsop, D., Gray, C. W. & Karran, E. H., 1999, In : Alzheimer's Reports. 2, p. 171-177 7 p.

    Research output: Contribution to journalJournal article

  70. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Howlett, D. R., James, S., Allsop, D. & Roberts, G. W., 1996, Neurobiology of Alzheimer's disease. Dawbarn, D. & Allen, S. J. (eds.). Oxford: BIOS Scientific Publishers, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  71. Published

    Variability of β-amyloid protein deposited lesions in Down's syndrome brains

    Ikeda, S., Tokuda, T., Yanagisawa, N., Kametani, F., Ohshima, T. & Allsop, D., 1994, In : The Tohoku Journal of Experimental Medicine. 174, 3, p. 189-198 10 p.

    Research output: Contribution to journalJournal article

  72. Published

    Gerstmann-Sträussler-Scheinker disease showing β-protein type cerebellar and cerebral amyloid angiopathy

    Ikeda, S. I., Yanagisawa, N., Allsop, D. & Glenner, G. G., 09/1994, In : Acta Neuropathologica. 88, 3, p. 262-266 5 p.

    Research output: Contribution to journalJournal article

  73. Published

    Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 12/1990, In : Human Pathology. 21, 12, p. 1221-1226 6 p.

    Research output: Contribution to journalJournal article

  74. Published

    Evidence of amyloid β-protein immunoreactive early plaque lesions in Down's syndrome brains

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 1989, In : Laboratory Investigation. 61, 1, p. 133-137 5 p.

    Research output: Contribution to journalJournal article

  75. Published

    Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases: an immunohistochemical study using amyloid β-protein antibody

    Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In : Laboratory Investigation. 60, 1, p. 113-122 10 p.

    Research output: Contribution to journalJournal article

  76. Published

    A study of the morphology and distribution of amyloid β protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome

    Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In : Progress in Clinical and Biological Research. 317, p. 313-323 11 p.

    Research output: Contribution to journalJournal article

  77. Published

    Immunogold labeling of cerebrovascular and neuritic plaque amyloid fibrils in Alzheimer's disease with an anti-β protein monoclonal antibody

    Ikeda, S., Wong, C. W., Allsop, D., Landon, M., Kidd, M. & Glenner, G. G., 1987, In : Laboratory Investigation. 57, 4, p. 446-9 4 p.

    Research output: Contribution to journalJournal article

  78. Published

    A study of the morphology and distribution of amyloid β-protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome

    Ikeda, S. I., Allsop, D. & Glenner, G. G., 1989, Alzheimer's disease and related disorders. Iqbal, K., Wisniewski, H. M. & Winblad, B. (eds.). New York: Alan R. Liss, p. 313-323 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  79. Published

    Amyloid β-protein pathology (in Japanese)

    Ikeda, S. I. & Allsop, D., 1990, 1990 Annual Review of Neurology (in Japanese). Goto, F., Takakura, K., Kinoshita, M., Yanagisawa, N. & Shimizu, T. (eds.). Tokyo: Chugai Igaku Publishers, p. 9-19 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  80. Published

    Designed glycopeptidomimetics disrupt protein−protein interactions mediating amyloid β‑peptide aggregation and restore neuroblastoma cell viability

    Kaffy, J., Brinet, D., Soulier, J-L., Tonali, N., Fera, K. F., Iacone, Y., Hoffmann, A. R. F., Khemtemourian, L., Crousse, B., Taylor, M. N., Allsop, D., Taverna, M., Lequin, O. & Ongeri, S., 10/03/2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2025-2040 16 p.

    Research output: Contribution to journalJournal article

  81. Published

    The immunoreactive profile at the N-terminal region of Aβ1-39/40 but not Aβ1-42 changes with transition from monomer/dimer to further peptide aggregates

    Kametani, F., Tanaka, K., Tokuda, T. & Allsop, D., 12/12/1995, In : Brain Research. 703, 1-2, p. 237-241 5 p.

    Research output: Contribution to journalJournal article

  82. Published

    Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity

    Kametani, F., Tanaka, K., Ishii, T., Ikeda, S., Kennedy, H. E. & Allsop, D., 15/03/1993, In : Biochemical and Biophysical Research Communications. 191, 2, p. 392-398 7 p.

    Research output: Contribution to journalJournal article

  83. Published

    Presenilins: in search of functionality

    Karran, E. H., Allsop, D., Christie, G., Davis, J., Gray, C., Mansfield, F. & Ward, R. V., 08/1998, In : Biochemical Society Transactions. 26, 3, p. 491-496 6 p.

    Research output: Contribution to journalJournal article

  84. Published

    Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

    Kasai, T., Tokuda, T., Ishigami, N., Sasayama, H., Foulds, P., Mitchell, D. J., Mann, D. M. A., Allsop, D. & Nakagawa, M., 2009, In : Acta Neuropathologica. 117, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal article

  85. Published

    Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aß oligomers

    Kasai, T., Tokuda, T., Taylor, M., Nakagawa, M. & Allsop, D., 8/06/2012, In : Biochemical and Biophysical Research Communications. 422, 3, p. 375-380 6 p.

    Research output: Contribution to journalJournal article

  86. Published

    Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples

    Kasai, T., Tokuda, T., Taylor, M., Kondo, M., Mann, D. M. A., Foulds, P., Nakagawa, M. & Allsop, D., 13/09/2013, In : Neuroscience Letters. 551, p. 17-22 6 p.

    Research output: Contribution to journalJournal article

  87. Published

    Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

    Kasai, T., Kondo, M., Ishii, R., Tanaka, A., Ataka, S., Shimada, H., Tomiyama, T., Mori, H., Taylor, M. N., Allsop, D., Nakagawa, M., Mizuno, T. & Tokuda, T., 10/04/2017, In : PLoS ONE. 12, 4

    Research output: Contribution to journalJournal article

  88. Published

    Increased levels of plasma total tau in adult Down syndrome

    Kasai, T., Tatebe, H., Kondo, M., Ishii, R., Ohmichi, T., Yeung, W. T. E., Morimoto, M., Chiyonobu, T., Terada, N., Allsop, D., Nakagawa, M., Mizuno, T. & Tokuda, T., 30/11/2017, In : PLoS ONE. 12, 11, 12 p., e0188802.

    Research output: Contribution to journalJournal article

  89. Published

    Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS: A comprehensive analysis on diagnostic and prognostic significance of plasma and CSF NfL, TDP-43, and tau

    Kasai, T., Kojima, Y., Ohmichi, T., Tatebe, H., Tsuji, Y., Noto, Y., Kitani-Morii, F., Shinomoto, M., Allsop, D., Mizuno, T. & Tokuda, T., 1/12/2019, In : Annals of Clinical and Translational Neurology. 6, 12, p. 2489-2502 14 p.

    Research output: Contribution to journalJournal article

  90. Published

    Senile plaque amyloid, paired helical filaments, and cerebrovascular amyloid in Alzheimer's disease are all deposits of the same protein

    Kidd, M., Allsop, D. & Landon, M., 1985, In : Lancet. 1, 8423, p. 278

    Research output: Contribution to journalJournal article

  91. Published

    Senile plaque amyloid

    Kidd, M., Allsop, D. & Landon, M., 1985, Modern approaches to the dementias, part 1: etiology and pathophysiology. Clifford Rose, F. (ed.). Basel: Karger, p. 114-126 13 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  92. Published

    Nanomechanical and nanothermal mapping of initial stages of amyloid fibres formation

    Kolosov, O., Tovee, P., Tinker-Mill, C. & Allsop, D., 15/09/2014, p. 29. 1 p.

    Research output: Contribution to conference - Without ISBN/ISSN Abstract

  93. Published

    Magnetite pollution nanoparticles in the human brain

    Maher, B. A., Ahmed, I., Karloukovski, V. V., MacLaren, D., Foulds, P., Allsop, D., Mann, D., Torres-Jardon, R. & Calderon-Garciduenas, L., 27/09/2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. 10797-10801 5 p.

    Research output: Contribution to journalJournal article

  94. Published

    α-Synuclein and the pathogenesis of Parkinson’s disease.

    Martin, F., Allsop, D., Williamson, S. J. M., Paleologou, K. E. & El-Agnaf, O. M. A., 2004, In : Protein and Peptide Letters. 11, 3, p. 229-237 9 p.

    Research output: Contribution to journalJournal article

  95. Published

    Fe(II)-induced DNA damage in α-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay.

    Martin, F., Williamson, S. J. M., Paleologou, K. E., Hewitt, R., El-Agnaf, O. M. A. & Allsop, D., 11/2003, In : Journal of Neurochemistry. 87, 3, p. 620-630 11 p.

    Research output: Contribution to journalJournal article

  96. Published

    Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis

    Martin, G. P., McDonald, K. R., Allsop, D., Diggle, P. J. & Leroi, I., 1/01/2020, In : Journal of Neurology. 267, 1, p. 214-227 14 p.

    Research output: Contribution to journalJournal article

  97. Published

    Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to β protein and cystatin C

    Maruyama, K., Ikeda, S., Ishihara, T., Allsop, D. & Yanagisawa, N., 03/1990, In : Stroke; a journal of cerebral circulation. 21, 3, p. 397-403 7 p.

    Research output: Contribution to journalJournal article

  98. Published

    Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

    Masad, A., Hayes, L., Tabner, B., Turnbull, S., Cooper, L., Fullwood, N. J., German, M., Kametani, F., El-Agnaf, O. M. A. & Allsop, D., 2007, In : FEBS Letters. 581, 18, p. 3489-3493 5 p.

    Research output: Contribution to journalJournal article

  99. Published

    The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

    Masad, A., Tabner, B. J., Mayes, J. & Allsop, D., 15/08/2011, In : Free Radical Biology and Medicine. 51, 4, p. 869-875 7 p.

    Research output: Contribution to journalJournal article

  100. Published

    Galantamine inhibits β-amyloid aggregation and cytotoxicity

    Matharu, B., Gibson, G., Parsons, R., Huckerby, T. N., Moore, S. A., Cooper, L. J., Millichamp, R., Allsop, D. & Austen, B., 15/05/2009, In : Journal of the Neurological Sciences. 280, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalJournal article

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