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Professor David Allsop

Formerly at Lancaster University

  1. 2003
  2. Published

    Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2003, In: Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents. 3, 4, p. 299-308 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. 2002
  4. Published

    Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 1/06/2002, In: Free Radical Biology and Medicine. 32, 11, p. 1076-1083 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Inherited frontotemporal dementia in 9 British families associated with intronic mutations in the tau gene.

    Pickering-Brown, S. M., Richardson, A. M. T., Snowden, J. S., McDonagh, A., Burns, A., Braudie, W., Baker, M., Yen, S-H., Hardy, J., Hutton, M., Davies, Y., Allsop, D., Craufurd, D., Neary, D. & Mann, D. M. A., 04/2002, In: Brain. 125, 4, p. 732-751 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. 2001
  7. Published

    Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

    Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps.

    Turnbull, S., Tabner, B. J., El-Agnaf, O. M. A., Twyman, L. J. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1154-1162 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro.

    Turnbull, S., Tabner, B. J., Moore, S., Davies, Y., El-Agnaf, O. M. A. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1163-1170 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide.

    Allsop, D., Gibson, G., Martin, I. K., Moore, S., Turnbull, S. & Twyman, L. J., 01/2001, In: Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 255-257 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2001, In: Current Topics in Medicinal Chemistry. 1, p. 483-493 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    The biology and molecular neuropathology of β-amyloid protein.

    Howlett, D. R., Allsop, D. & Karran, E. H., 2001, Neurobiology of Alzheimer's disease . Dawbarn, D. & Allen, S. J. (eds.). 2nd ed. ed. Oxford: Oxford University Press, p. 75-102 28 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  13. 2000
  14. Published

    Pick's disease is associated with mutations in the tau gene.

    Pickering-Brown, S., Baker, M., Yen, S-H., Liu, W-K., Hasegawa, M., Cairns, N., Lantos, P. L., Rossor, M., Iwatsubo, T., Davies, Y., Allsop, D., Furlong, R., Owen, F., Hardy, J., David Mann, D. & Hutton, M., 12/2000, In: Annals of Neurology. 48, 6, p. 589-867 279 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells

    Gardner, R. C., Assinder, S. J., Christie, G., Mason, G. G. F., Markwell, R., Wadsworth, H., McLaughlin, M., King, R., Chabot-Fletcher, M. C., Breton, J., Allsop, D. & Rivett, A. J., 2000, In: Biochemical Journal. 346, p. 447-454 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Introduction to Alzheimer's disease.

    Allsop, D., 2000, Alzheimer's disease : methods and protocols. Hooper, N. (ed.). Totawa, New Jersey: Humana Press, p. 1-21 21 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  17. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In: Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to Journal/MagazineLiterature reviewpeer-review

  18. 1999
  19. Published

    A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

    Twyman, L. J. & Allsop, D., 12/1999, In: Tetrahedron Letters. 40, 52, p. 9383-9384 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

    Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A., & 4 othersGardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In: Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Biological activity associated with a high molecular weight form of β-amyloid.

    Howlett, D. R., Ward, R. V., Bresciani, L., Jennings, K. H., Christie, G., Allsop, D., Gray, C. W. & Karran, E. H., 1999, In: Alzheimer's Reports. 2, p. 171-177 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Characterization of an α-secretase candidate from human brain using a new western blot assay

    Evin, G., Reed, G., Tanner, J. E., Li, Q. X., Culvenor, J. G., Fuller, S. J., Wadsworth, H., Allsop, D., Ward, R. V., Karran, E. H., Gray, C. W., Hartmann, T., Lichtenthaler, S. F., Weidemann, A., Beyreuther, K. & Masters, C. L., 1999, Alzheimer's disease and related disorders. Iqbal, K., Swaab, D. F., Winblad, B. & Wisniewski, H. M. (eds.). Wiley, p. 411-418 8 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  23. 1998
  24. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Presenilins: in search of functionality

    Karran, E. H., Allsop, D., Christie, G., Davis, J., Gray, C., Mansfield, F. & Ward, R. V., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 491-496 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. 1997
  27. Published

    Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

    Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In: Nature Medicine. 3, 9, p. 1016-1020 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  28. Published

    Studies on inhibition of β-amyloid formation in APP-751-transfected IMR-32 cells, and SPA4CT-transfected SHSY5Y cells

    Allsop, D., Christie, G., Gray, C., Holmes, S., Markwell, R., Owen, D., Smith, L., Wadsworth, H., Ward, R. V., Hartmann, T., Lichtenthaler, S. F., Evin, G., Fuller, S., Tanner, J., Masters, C. L., Beyreuther, K. & Roberts, G. W., 1997, Alzheimer's disease: biology, diagnosis and therapeutics. Iqbal, K., Winblad, B., Nishimura, T., Takeda, M. & Wisniewski, H. M. (eds.). New York: Wiley, p. 717-727 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  29. 1996
  30. Published

    Effect of aluminium on expression and processing of amyloid precursor protein

    Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., Rima, B. K., Morris, C., Candy, J. M. & Edwardson, J. A., 15/11/1996, In: Journal of Neuroscience Research. 46, 4, p. 395-403 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In: Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Howlett, D. R., James, S., Allsop, D. & Roberts, G. W., 1996, Neurobiology of Alzheimer's disease. Dawbarn, D. & Allen, S. J. (eds.). Oxford: BIOS Scientific Publishers, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  33. 1995
  34. Published

    The immunoreactive profile at the N-terminal region of Aβ1-39/40 but not Aβ1-42 changes with transition from monomer/dimer to further peptide aggregates

    Kametani, F., Tanaka, K., Tokuda, T. & Allsop, D., 12/12/1995, In: Brain Research. 703, 1-2, p. 237-241 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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