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Professor David Allsop

Professor

  1. Published

    3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide.

    Allsop, D., Gibson, G., Martin, I. K., Moore, S., Turnbull, S. & Twyman, L. J., 01/2001, In : Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 255-257 3 p.

    Research output: Contribution to journalJournal article

  2. Published

    A demonstration of the advantages of immunostaining in the quantification of amyloid plaque deposits

    Gentleman, S. M., Bruton, C., Allsop, D., Lewis, S. J., Polak, J. M. & Roberts, G. W., 1989, In : Histochemistry. 92, 4, p. 355-358 4 p.

    Research output: Contribution to journalJournal article

  3. Published

    A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson’s disease

    Foulds, P., Diggle, P., Mitchell, J. D., Parker, A., Hasegawa, M., Masuda-Suzukake, M., Mann, D. M. A. & Allsop, D., 29/08/2013, In : Scientific Reports. 3, 6 p., 2540.

    Research output: Contribution to journalJournal article

  4. Published

    A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease

    Foulds, PG., Diggle, P., Mitchell, JD., Parker, A., Hasegawa, M., Masuda-Suzukake, M., Mann, DM. & Allsop, D., 2013, In : Scientific Reports. 3, 6 p., 2540.

    Research output: Contribution to journalJournal article

  5. Published

    A monoclonal antibody to common acute lymphoblastic leukemia antigen (neutral endopeptidase) immunostains senile plaques in the brains of patients with Alzheimer's disease

    Sato, M., Ikeda, K., Haga, S., Allsop, D. & Ishii, T., 2/01/1991, In : Neuroscience Letters. 121, 1-2, p. 271-273 3 p.

    Research output: Contribution to journalJournal article

  6. Published

    A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation

    Allsop, D., Taylor, M. N., Fullwood, N. J., Michael, M., Aggidis, A., Vincent, S. & Dale, M., 1/11/2017, In : Journal of Prevention of Alzheimer's Disease. 4, 4, p. 385-386 2 p.

    Research output: Contribution to journalMeeting abstract

  7. Published

    A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's Disease

    Parthsarathy, V., McClean, P. L., Hölscher, C., Taylor, M., Tinker, C., Jones, G., Kolosov, O., Salvati, E., Gregori, M., Masserini, M. & Allsop, D., 2013, In : PLoS ONE. 8, 1, 11 p., e54769.

    Research output: Contribution to journalJournal article

  8. Published

    A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative diseases

    Tabner, B., Moore, S., Mayes, J. & Allsop, D., 2013, Brain diseases and metalloproteins. Brown, D. R. (ed.). Boca Raton, Fla.: Pan Stanford, p. 11-32 22 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  9. Published

    A possible unified nomenclature for Alzheimer amyloid protein, precursors and gene

    Allsop, D., 01/1990, In : Neurobiology of Aging. 11, 1, p. 69 1 p.

    Research output: Contribution to journalJournal article

  10. Published

    A preliminary electron microscopic investigation into the interaction between Aβ1-42 peptide and a novel nanoliposome- coupled retro-inverso peptide inhibitor, developed as a potential treatment for Alzheimer's disease

    Sherer, M., Fullwood, N. J., Taylor, M. & Allsop, D., 1/10/2015, In : Journal of Physics: Conference Series. 644, 1, 4 p., 012040.

    Research output: Contribution to journalJournal article

  11. Published

    A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

    Twyman, L. J. & Allsop, D., 12/1999, In : Tetrahedron Letters. 40, 52, p. 9383-9384 2 p.

    Research output: Contribution to journalJournal article

  12. Published

    A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein.

    Tabner, B. J., Turnbull, S., King, J., Benson, F. E., El-Agnaf, O. M. A. & Allsop, D., 07/2006, In : Free Radical Research. 40, 7, p. 731-739 9 p.

    Research output: Contribution to journalJournal article

  13. Published

    A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.

    El-Agnaf, O. M. A., Paleologou, K. E., Greer, B., Abogrein, A. M., King, J., Salem, S. A., Fullwood, N. J., Benson, F. E., Hewitt, R., Ford, K. J., Martin, F., Harriott, P., Cookson, M. R. & Allsop, D., 08/2004, In : FASEB Journal. 18, 11, p. 1315-1317 3 p.

    Research output: Contribution to journalJournal article

  14. Published

    A study of the morphology and distribution of amyloid β protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome

    Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In : Progress in Clinical and Biological Research. 317, p. 313-323 11 p.

    Research output: Contribution to journalJournal article

  15. Published

    A study of the morphology and distribution of amyloid β-protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome

    Ikeda, S. I., Allsop, D. & Glenner, G. G., 1989, Alzheimer's disease and related disorders. Iqbal, K., Wisniewski, H. M. & Winblad, B. (eds.). New York: Alan R. Liss, p. 313-323 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  16. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In : Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to journalJournal article

  17. Published

    Aggregation of Alzheimer's peptides

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In : Biochemical Society Transactions. 22, 1, p. 16S 1 p.

    Research output: Contribution to journalJournal article

  18. Published

    Alzheimer amyloid β/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 14/06/1991, In : Brain Research. 551, 1-2, p. 1-9 9 p.

    Research output: Contribution to journalJournal article

  19. Published

    Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

    Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A. & 4 others, Gardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In : Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

    Research output: Contribution to journalJournal article

  20. Published

    Amyloid deposition as the central event in the aetiology of Alzheimer's disease

    Hardy, J. & Allsop, D., 1991, In : Trends in Pharmacological Sciences. 12, 10, p. 383-388 6 p.

    Research output: Contribution to journalJournal article

  21. Published

    Amyloid β-peptide and Alzheimer's disease

    Allsop, D. & Mayes, J., 18/08/2014, In : Essays in Biochemistry. 56, p. 99-110 12 p., 7.

    Research output: Contribution to journalLiterature review

  22. Published

    Amyloid β-protein pathology (in Japanese)

    Ikeda, S. I. & Allsop, D., 1990, 1990 Annual Review of Neurology (in Japanese). Goto, F., Takakura, K., Kinoshita, M., Yanagisawa, N. & Shimizu, T. (eds.). Tokyo: Chugai Igaku Publishers, p. 9-19 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  23. Published

    Amyloidosis in Alzheimer's disease

    Allsop, D. & Williams, C. H., 1994, In : Biochemical Society Transactions. 22, 1, p. 171-175 5 p.

    Research output: Contribution to journalJournal article

  24. Published

    Amyloids in neurodegenerative diseases: immunocytochemical studies

    Roberts, G. W., Lofthouse, R., Allsop, D., Landon, M., Kidd, M., Prusiner, S. B. & Crowe, T. J., 1990, Proceedings of II International Symposium on Unconventional Viruses of the Central Nervous System. Court, L. A. (ed.). Paris, p. 602-616 15 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  25. Published

    Amyloid-β fibrils in Alzheimer's Disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species

    Mayes, J., Tinker-Mill, C., Kolosov, O., Zhang, H., Tabner, B. & Allsop, D., 25/04/2014, In : Journal of Biological Chemistry. 289, p. 12052-12062 11 p.

    Research output: Contribution to journalJournal article

  26. Published

    An investigation into the lipid-binding properties of α-, β- and γ-synucleins in human brain and cerebrospinal fluid

    Salem, S. A., Allsop, D., Mann, D. M. A., Tokuda, T. & El-Agnaf, O. M. A., 19/09/2007, In : Experimental Brain Research. 1170, p. 103-111 9 p.

    Research output: Contribution to journalJournal article

  27. Published

    An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

    Walsh, D. M., Williams, C. H., Kennedy, H. E. & Allsop, D., 1994, In : Biochemical Society Transactions. 22, 1, p. 14S 1 p.

    Research output: Contribution to journalJournal article

  28. Published

    Antibody staining of cerebral amyloid in Alzheimer’s disease, Down’s syndrome, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome

    Allsop, D., Roberts, G. W., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Crowe, T. J., 1987, Advancing Frontiers in Alzheimer’s Disease Research. Glenner, G. G. & Wurtman, J. (eds.). Austin: University of Texas Press, p. 137-153 17 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  29. Published

    Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis

    Martin, G. P., McDonald, K. R., Allsop, D., Diggle, P. J. & Leroi, I., 1/01/2020, In : Journal of Neurology. 267, 1, p. 214-227 14 p.

    Research output: Contribution to journalJournal article

  30. Published

    Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

    Kasai, T., Kondo, M., Ishii, R., Tanaka, A., Ataka, S., Shimada, H., Tomiyama, T., Mori, H., Taylor, M. N., Allsop, D., Nakagawa, M., Mizuno, T. & Tokuda, T., 10/04/2017, In : PLoS ONE. 12, 4

    Research output: Contribution to journalJournal article

  31. Published

    Biochemistry of cerebral amyloid in Alzheimer’s disease, the unconventional slow virus diseases, and Icelandic cerebrovascular amyloidosis

    Allsop, D., 1986, Amyloidosis. Marrink, J. & van Rijswijk, M. H. (eds.). Dordrecht: Martinus Nijhoff Publishers/ Brill Academic, p. 243-253 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  32. Published

    Biological activity associated with a high molecular weight form of β-amyloid.

    Howlett, D. R., Ward, R. V., Bresciani, L., Jennings, K. H., Christie, G., Allsop, D., Gray, C. W. & Karran, E. H., 1999, In : Alzheimer's Reports. 2, p. 171-177 7 p.

    Research output: Contribution to journalJournal article

  33. Published

    Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer’s disease

    Paraskevaidi, M., Morais, C., Freitas, D., Lima, K., Mann, D., Allsop, D., Martin-Hirsch, P. & Martin, F. L., 21/12/2018, In : Analyst. 143, 24, p. 5959-5964 6 p.

    Research output: Contribution to journalJournal article

  34. Published

    Both the D-(+) and L-(-) enantiomers of nicotine inhibit Aβ aggregation and cytotoxicity.

    Moore, S. A., Huckerby, T. N., Gibson, G. L., Fullwood, N. J., Turnbull, I., Tabner, B. J., El-Agnaf, O. M. A. & Allsop, D., 01/2004, In : Biochemistry. 43, 3, p. 819-826 8 p.

    Research output: Contribution to journalJournal article

  35. Published

    Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage

    Ohshima, T., Endo, T., Nukui, H., Ikeda, S., Allsop, D. & Onaya, T., 03/1990, In : Stroke; a journal of cerebral circulation. 21, 3, p. 480-483 4 p.

    Research output: Contribution to journalJournal article

  36. Published

    Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein

    Allsop, D., Ikeda, S., Bruce, M. & Glenner, G. G., 5/10/1988, In : Neuroscience Letters. 92, 2, p. 234-239 6 p.

    Research output: Contribution to journalJournal article

  37. Published

    Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells

    Gardner, R. C., Assinder, S. J., Christie, G., Mason, G. G. F., Markwell, R., Wadsworth, H., McLaughlin, M., King, R., Chabot-Fletcher, M. C., Breton, J., Allsop, D. & Rivett, A. J., 2000, In : Biochemical Journal. 346, p. 447-454 8 p.

    Research output: Contribution to journalJournal article

  38. Published

    Characterization of an α-secretase candidate from human brain using a new western blot assay

    Evin, G., Reed, G., Tanner, J. E., Li, Q. X., Culvenor, J. G., Fuller, S. J., Wadsworth, H., Allsop, D., Ward, R. V., Karran, E. H., Gray, C. W., Hartmann, T., Lichtenthaler, S. F., Weidemann, A., Beyreuther, K. & Masters, C. L., 1999, Alzheimer's disease and related disorders. Iqbal, K., Swaab, D. F., Winblad, B. & Wisniewski, H. M. (eds.). Wiley, p. 411-418 8 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  39. Published

    Chloroplast development in normal and mutant lines of barley

    Atkinson, Y. E., Allsop, D. & Bradbeer, J. W., 1981, Photosynthesis V: chloroplast development. Akoyunoglou, G. (ed.). Philadelphia: Balaban International Science Services, p. 797-808 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  40. Published

    CNS amyloid proteins in neurodegenerative diseases

    Roberts, G. W., Lofthouse, R., Allsop, D., Landon, M., Kidd, M., Prusiner, S. B. & Crow, T. J., 1988, In : Neurology. 38, 10, p. 1534-40 7 p.

    Research output: Contribution to journalJournal article

  41. Published

    Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS: A comprehensive analysis on diagnostic and prognostic significance of plasma and CSF NfL, TDP-43, and tau

    Kasai, T., Kojima, Y., Ohmichi, T., Tatebe, H., Tsuji, Y., Noto, Y., Kitani-Morii, F., Shinomoto, M., Allsop, D., Mizuno, T. & Tokuda, T., 1/12/2019, In : Annals of Clinical and Translational Neurology. 6, 12, p. 2489-2502 14 p.

    Research output: Contribution to journalJournal article

  42. Published

    Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 23/01/2003, In : Neuroscience Letters. 336, 3, p. 159-162 4 p.

    Research output: Contribution to journalJournal article

  43. Published

    Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

    Masad, A., Hayes, L., Tabner, B., Turnbull, S., Cooper, L., Fullwood, N. J., German, M., Kametani, F., El-Agnaf, O. M. A. & Allsop, D., 2007, In : FEBS Letters. 581, 18, p. 3489-3493 5 p.

    Research output: Contribution to journalJournal article

  44. Published

    Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples

    Kasai, T., Tokuda, T., Taylor, M., Kondo, M., Mann, D. M. A., Foulds, P., Nakagawa, M. & Allsop, D., 13/09/2013, In : Neuroscience Letters. 551, p. 17-22 6 p.

    Research output: Contribution to journalJournal article

  45. Published

    Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease.

    Tokuda, T., Salem, S. A., Allsop, D., Mizuno, T., Nakagawa, M., Qureshi, M. M., Locascio, J. J., Schlossmacher, M. G. & El-Agnaf, O., 13/10/2006, In : Biochemical and Biophysical Research Communications. 349, 1, p. 162-166 5 p.

    Research output: Contribution to journalJournal article

  46. Published

    Designed glycopeptidomimetics disrupt protein−protein interactions mediating amyloid β‑peptide aggregation and restore neuroblastoma cell viability

    Kaffy, J., Brinet, D., Soulier, J-L., Tonali, N., Fera, K. F., Iacone, Y., Hoffmann, A. R. F., Khemtemourian, L., Crousse, B., Taylor, M. N., Allsop, D., Taverna, M., Lequin, O. & Ongeri, S., 10/03/2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2025-2040 16 p.

    Research output: Contribution to journalJournal article

  47. Published

    Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide

    Austen, B. M., Paleologou, K. E., Ali, S. A. E., Qureshi, M. M., Allsop, D. & El-Agnaf, O. M. A., 2008, In : Biochemistry. 47, 7, p. 1984-1992 9 p.

    Research output: Contribution to journalJournal article

  48. Published

    Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies

    Paleologou, K. E., Kragh, C. L., Mann, D. M. A., Salem, S. A., Al-Shami, R., Allsop, D., Hassan, A. H., Jensen, P. H. & El-Agnaf, O. M. A., 2009, In : Brain. 132, 4, p. 1093-1101 9 p.

    Research output: Contribution to journalJournal article

  49. Published

    Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Curran, M. D., Gibson, M. J., Court, J. A., Schlossmacher, M. G. & Allsop, D., 2006, In : FASEB Journal. 20, 3, p. 419-425 7 p.

    Research output: Contribution to journalJournal article

  50. Published

    Development and automation of a novel [18F]Fprosthetic group, 2-[18F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

    Morris, O., Gregory, J., Kadirvel, M., Henderson, F., Blykers, A., McMahon, A., Taylor, M. N., Allsop, D., Allan, S., Grigg, J., Boutin, H. & Prenant, C., 10/2016, In : Applied Radiation and Isotopes. 116, p. 120-127 8 p.

    Research output: Contribution to journalJournal article

  51. Published

    Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimer's disease

    Taylor, M., Moore, S., Mayes, J., Parkin, E., Beeg, M., Canovi, M., Gobbi, M., Mann, D. M. A. & Allsop, D., 2010, In : Biochemistry. 49, 15, p. 3261-3272 12 p.

    Research output: Contribution to journalJournal article

  52. Published

    Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes

    Obasse, I. C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 6/12/2017, In : Interface Focus. 7, 6, 11 p., 20160127.

    Research output: Contribution to journalJournal article

  53. Published

    Differential diagnosis of Alzheimer’s disease using spectrochemical analysis of blood

    Paraskevaidi, M., Morais, C., Lima, K., Snowden, J., Saxon, J., Richardson, A., Jones, M., Mann, D., Allsop, D., Martin-Hirsch, P. & Martin, F., 19/09/2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 38, p. E7929–E7938 10 p.

    Research output: Contribution to journalJournal article

  54. Published

    Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2003, In : Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents. 3, 4, p. 299-308 10 p.

    Research output: Contribution to journalJournal article

  55. Published

    Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

    Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In : Nature Medicine. 3, 9, p. 1016-1020 5 p.

    Research output: Contribution to journalJournal article

  56. Published

    Donepezil for severe Alzheimer's disease.

    Allsop, D., Martin, F., Moore, S. & Fullwood, N. J., 29/07/2006, In : Lancet. 368, 9533, p. 361-362 2 p.

    Research output: Contribution to journalJournal article

  57. Published

    Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 12/1990, In : Human Pathology. 21, 12, p. 1221-1226 6 p.

    Research output: Contribution to journalJournal article

  58. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

    Allsop, D., Haga, S. I., Haga, C., Ikeda, S. I., Mann, D. M. & Ishii, T., 12/1990, In : Neuropathology and Applied Neurobiology. 15, 6, p. 531-542 12 p.

    Research output: Contribution to journalJournal article

  59. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons: evidence for a neuronal origin of senile plaque amyloid

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Molecular biology and genetics of Alzheimer disease. Miyatake, T., Selkoe, D. J. & Ihara, Y. (eds.). Amsterdam: Elsevier, p. 95-104 10 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  60. Published

    Effect of aluminium on expression and processing of amyloid precursor protein

    Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., Rima, B. K., Morris, C., Candy, J. M. & Edwardson, J. A., 15/11/1996, In : Journal of Neuroscience Research. 46, 4, p. 395-403 9 p.

    Research output: Contribution to journalJournal article

  61. Published

    Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide

    Taylor, M., Moore, S., Mourtas, S., Niarakis, A., Re, F., Zona, C., La Ferla, B., Nicotra, F., Masserini, M., Antimisiaris, S. G., Gregori, M. & Allsop, D., 10/2011, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 7, 5, p. 541-550 10 p.

    Research output: Contribution to journalJournal article

  62. Published

    Effects of different isoforms of apoE on aggregation of the α- synuclein protein implicated in Parkinson's disease

    Nouri Emamzadeh, F., Aojula, H., McHugh, P. & Allsop, D., 8/04/2016, In : Neuroscience Letters. 618, p. 146-151 6 p.

    Research output: Contribution to journalJournal article

  63. Published

    Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In : Neuroscience Letters. 161, 1, p. 17-20 4 p.

    Research output: Contribution to journalJournal article

  64. Published

    Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme

    Williams, C. H., Yamamoto, T., Walsh, D. M. & Allsop, D., 15/09/1993, In : Biochemical Journal. 294 , 3, p. 681-684 4 p.

    Research output: Contribution to journalJournal article

  65. Published

    Evidence for a neuronal origin of senile plaques in Down's syndrome brains

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Basic and therapeutic aspects of Alzheimer's and Parkinson's diseases. Nagatsu, T. (ed.). New York: Plenum Press, Vol. 1. p. 83-86 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  66. Published

    Evidence for the derivation of a peptide ligand from the amyloid β protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. I. & Glenner, G. G., 1989, Alzheimer's disease and related disorders: proceedings of the First International Conference on Alzheimer's Disease and Related Disorders, held in Las Vegas, Nevada, September 5-9, 1988. Iqbal, K., Wisniewski, H. M. & Winblad, B. (eds.). New York: Alan R. Liss, p. 893-902 10 p. (Progress in clinical and biological research; vol. 317).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  67. Published

    Evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. & Glenner, G. G., 1989, In : Progress in Clinical and Biological Research. 317, p. 893-902 10 p.

    Research output: Contribution to journalJournal article

  68. Published

    Evidence of amyloid β-protein immunoreactive early plaque lesions in Down's syndrome brains

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 1989, In : Laboratory Investigation. 61, 1, p. 133-137 5 p.

    Research output: Contribution to journalJournal article

  69. Published

    Fe(II)-induced DNA damage in α-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay.

    Martin, F., Williamson, S. J. M., Paleologou, K. E., Hewitt, R., El-Agnaf, O. M. A. & Allsop, D., 11/2003, In : Journal of Neurochemistry. 87, 3, p. 620-630 11 p.

    Research output: Contribution to journalJournal article

  70. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In : Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to journalJournal article

  71. Published

    Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

    Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In : Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

    Research output: Contribution to journalJournal article

  72. Published

    Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 1/06/2002, In : Free Radical Biology and Medicine. 32, 11, p. 1076-1083 8 p.

    Research output: Contribution to journalJournal article

  73. Published

    Galantamine inhibits β-amyloid aggregation and cytotoxicity

    Matharu, B., Gibson, G., Parsons, R., Huckerby, T. N., Moore, S. A., Cooper, L. J., Millichamp, R., Allsop, D. & Austen, B., 15/05/2009, In : Journal of the Neurological Sciences. 280, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalJournal article

  74. Published

    Gelatinase A not α-secretase?

    Walsh, D. M., Williams, C. H., Kennedy, H. E., Allsop, D. & Murphy, G., 1994, In : Nature. 367, 6458, p. 27-28 2 p.

    Research output: Contribution to journalJournal article

  75. Published

    Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 1/07/2003, In : Biochemistry. 42, 25, p. 7675-7681 7 p.

    Research output: Contribution to journalJournal article

  76. Published

    Gerstmann-Sträussler-Scheinker disease showing β-protein type cerebellar and cerebral amyloid angiopathy

    Ikeda, S. I., Yanagisawa, N., Allsop, D. & Glenner, G. G., 09/1994, In : Acta Neuropathologica. 88, 3, p. 262-266 5 p.

    Research output: Contribution to journalJournal article

  77. Published

    High affinity amyloid peptide β/A4 binding sites and a putative "APP secretase" in rat brain

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Proceedings of the XIth International Congress of Neuropathology: The Japanese Society of Neuropathology. Sasaki, Japan, p. 119-127 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  78. Published

    High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

    Fukumoto, H., Tokuda, T., Kasai, T., Ishigami, N., Hidaka, H., Kondo, M., Allsop, D. & Nakagawa, M., 2010, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24, 8, p. 2716-2726 11 p.

    Research output: Contribution to journalJournal article

  79. Published

    Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research

    Neill, D., Hughes, D., Edwardson, J. A., Rima, B. K. & Allsop, D., 1994, In : Journal of Neuroscience Research. 39, 4, p. 482-493 12 p.

    Research output: Contribution to journalJournal article

  80. Published

    Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia.

    Tabner, B. J., El-Agnaf, O. M. A., Turnbull, S., German, M. J., Paleologou, K. E., Hayashi, Y., Cooper, L. J., Fullwood, N. & Allsop, D., 28/10/2005, In : Journal of Biological Chemistry. 280, 43, p. 35789-35792 4 p.

    Research output: Contribution to journalJournal article

  81. Published

    Hypothesis: soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease

    Tabner, B. J., Mayes, J. & Allsop, D., 8/10/2010, In : International Journal of Alzheimer's Disease. 2011, 6 p., 546380.

    Research output: Contribution to journalJournal article

  82. Published

    Immunogold labeling of cerebrovascular and neuritic plaque amyloid fibrils in Alzheimer's disease with an anti-β protein monoclonal antibody

    Ikeda, S., Wong, C. W., Allsop, D., Landon, M., Kidd, M. & Glenner, G. G., 1987, In : Laboratory Investigation. 57, 4, p. 446-9 4 p.

    Research output: Contribution to journalJournal article

  83. Published

    Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to β protein and cystatin C

    Maruyama, K., Ikeda, S., Ishihara, T., Allsop, D. & Yanagisawa, N., 03/1990, In : Stroke; a journal of cerebral circulation. 21, 3, p. 397-403 7 p.

    Research output: Contribution to journalJournal article

  84. Published

    Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer disease

    Allsop, D., Wong, C. W., Ikeda, S., Landon, M., Kidd, M. & Glenner, G. G., 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 8, p. 2790-2794 5 p.

    Research output: Contribution to journalJournal article

  85. Published

    Immunohistochemical studies of cerebrovascular amyloid deposits in brains with cerebral amyloid angiopathy

    Shoji, S., Maruyama, K., Ikeda, S., Yanagisawa, N., Ishihara, T. & Allsop, D., 1989, 1988 Annual Report of the Primary Amyloidosis Research Committee. Tomanaga, M. (ed.). The Ministry of Health and Welfare of Japan, p. 27-30 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  86. Published

    Increased levels of plasma total tau in adult Down syndrome

    Kasai, T., Tatebe, H., Kondo, M., Ishii, R., Ohmichi, T., Yeung, W. T. E., Morimoto, M., Chiyonobu, T., Terada, N., Allsop, D., Nakagawa, M., Mizuno, T. & Tokuda, T., 30/11/2017, In : PLoS ONE. 12, 11, 12 p., e0188802.

    Research output: Contribution to journalJournal article

  87. Published

    Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

    Kasai, T., Tokuda, T., Ishigami, N., Sasayama, H., Foulds, P., Mitchell, D. J., Mann, D. M. A., Allsop, D. & Nakagawa, M., 2009, In : Acta Neuropathologica. 117, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal article

  88. Published

    Induction of cellular oxidative stress by the β-amyloid peptide involved in Alzheimer's disease.

    Gibson, G. L., Allsop, D. & Austen, B. M., 2004, In : Protein and Peptide Letters. 11, 3, p. 257-270 14 p.

    Research output: Contribution to journalJournal article

  89. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In : Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to journalJournal article

  90. Published

    Inherited frontotemporal dementia in 9 British families associated with intronic mutations in the tau gene.

    Pickering-Brown, S. M., Richardson, A. M. T., Snowden, J. S., McDonagh, A., Burns, A., Braudie, W., Baker, M., Yen, S-H., Hardy, J., Hutton, M., Davies, Y., Allsop, D., Craufurd, D., Neary, D. & Mann, D. M. A., 04/2002, In : Brain. 125, 4, p. 732-751 20 p.

    Research output: Contribution to journalJournal article

  91. Published

    Introduction to Alzheimer's disease.

    Allsop, D., 2000, Alzheimer's disease : methods and protocols. Hooper, N. (ed.). Totawa, New Jersey: Humana Press, p. 1-21 21 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  92. Published

    Isolated senile plaque cores in Alzheimer's disease and Down's syndrome show differences in morphology

    Allsop, D., Kidd, M., Landon, M. & Tomlinson, A., 1986, In : Journal of Neurology, Neurosurgery and Psychiatry. 49, 8, p. 886-892 7 p.

    Research output: Contribution to journalJournal article

  93. Published

    Liposome delivery systems for the treatment of Alzheimer’s disease

    Ross, C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 12/12/2018, In : International Journal of Nanomedicine. 2018, 13, p. 8507-8522 16 p.

    Research output: Contribution to journalJournal article

  94. Published

    Magnetite pollution nanoparticles in the human brain

    Maher, B. A., Ahmed, I., Karloukovski, V. V., MacLaren, D., Foulds, P., Allsop, D., Mann, D., Torres-Jardon, R. & Calderon-Garciduenas, L., 27/09/2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. 10797-10801 5 p.

    Research output: Contribution to journalJournal article

  95. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Allsop, D., Clements, A., Kennedy, H. E., Walsh, D. M. & Williams, C. H., 1994, Amyloid precursor protein in development, ageing and Alzheimer's disease. Berlin: Springer Verlag, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  96. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Howlett, D. R., James, S., Allsop, D. & Roberts, G. W., 1996, Neurobiology of Alzheimer's disease. Dawbarn, D. & Allen, S. J. (eds.). Oxford: BIOS Scientific Publishers, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  97. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In : Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to journalJournal article

  98. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In : Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to journalLiterature review

  99. Published

    Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

    Allsop, D., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Gardner, A., 1986, In : Neuroscience Letters. 68, 2, p. 252-6 5 p.

    Research output: Contribution to journalJournal article

  100. Published

    Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases: an immunohistochemical study using amyloid β-protein antibody

    Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In : Laboratory Investigation. 60, 1, p. 113-122 10 p.

    Research output: Contribution to journalJournal article

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