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Professor David Allsop

Professor

  1. Journal article
  2. Published

    Presenilins: in search of functionality

    Karran, E. H., Allsop, D., Christie, G., Davis, J., Gray, C., Mansfield, F. & Ward, R. V., 08/1998, In : Biochemical Society Transactions. 26, 3, p. 491-496 6 p.

    Research output: Contribution to journalJournal article

  3. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In : Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to journalJournal article

  4. Published

    Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

    Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In : Nature Medicine. 3, 9, p. 1016-1020 5 p.

    Research output: Contribution to journalJournal article

  5. Published

    Effect of aluminium on expression and processing of amyloid precursor protein

    Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., Rima, B. K., Morris, C., Candy, J. M. & Edwardson, J. A., 15/11/1996, In : Journal of Neuroscience Research. 46, 4, p. 395-403 9 p.

    Research output: Contribution to journalJournal article

  6. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In : Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to journalJournal article

  7. Published

    The immunoreactive profile at the N-terminal region of Aβ1-39/40 but not Aβ1-42 changes with transition from monomer/dimer to further peptide aggregates

    Kametani, F., Tanaka, K., Tokuda, T. & Allsop, D., 12/12/1995, In : Brain Research. 703, 1-2, p. 237-241 5 p.

    Research output: Contribution to journalJournal article

  8. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In : Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to journalJournal article

  9. Published

    Gerstmann-Sträussler-Scheinker disease showing β-protein type cerebellar and cerebral amyloid angiopathy

    Ikeda, S. I., Yanagisawa, N., Allsop, D. & Glenner, G. G., 09/1994, In : Acta Neuropathologica. 88, 3, p. 262-266 5 p.

    Research output: Contribution to journalJournal article

  10. Published

    Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research

    Neill, D., Hughes, D., Edwardson, J. A., Rima, B. K. & Allsop, D., 1994, In : Journal of Neuroscience Research. 39, 4, p. 482-493 12 p.

    Research output: Contribution to journalJournal article

  11. Published

    Variability of β-amyloid protein deposited lesions in Down's syndrome brains

    Ikeda, S., Tokuda, T., Yanagisawa, N., Kametani, F., Ohshima, T. & Allsop, D., 1994, In : The Tohoku Journal of Experimental Medicine. 174, 3, p. 189-198 10 p.

    Research output: Contribution to journalJournal article

  12. Published

    Amyloidosis in Alzheimer's disease

    Allsop, D. & Williams, C. H., 1994, In : Biochemical Society Transactions. 22, 1, p. 171-175 5 p.

    Research output: Contribution to journalJournal article

  13. Published

    Aggregation of Alzheimer's peptides

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In : Biochemical Society Transactions. 22, 1, p. 16S 1 p.

    Research output: Contribution to journalJournal article

  14. Published

    An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

    Walsh, D. M., Williams, C. H., Kennedy, H. E. & Allsop, D., 1994, In : Biochemical Society Transactions. 22, 1, p. 14S 1 p.

    Research output: Contribution to journalJournal article

  15. Published

    Gelatinase A not α-secretase?

    Walsh, D. M., Williams, C. H., Kennedy, H. E., Allsop, D. & Murphy, G., 1994, In : Nature. 367, 6458, p. 27-28 2 p.

    Research output: Contribution to journalJournal article

  16. Published

    Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In : Neuroscience Letters. 161, 1, p. 17-20 4 p.

    Research output: Contribution to journalJournal article

  17. Published

    Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme

    Williams, C. H., Yamamoto, T., Walsh, D. M. & Allsop, D., 15/09/1993, In : Biochemical Journal. 294 , 3, p. 681-684 4 p.

    Research output: Contribution to journalJournal article

  18. Published

    Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity

    Kametani, F., Tanaka, K., Ishii, T., Ikeda, S., Kennedy, H. E. & Allsop, D., 15/03/1993, In : Biochemical and Biophysical Research Communications. 191, 2, p. 392-398 7 p.

    Research output: Contribution to journalJournal article

  19. Published

    Quantification of βA4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

    Gentleman, S. M., Williams, B., Royston, M. C., Jagoe, R., Clinton, J., Perry, R. H., Ince, P. G., Allsop, D., Polak, J. M. & Roberts, G. W., 3/08/1992, In : Neuroscience Letters. 142, 1, p. 9-12 4 p.

    Research output: Contribution to journalJournal article

  20. Published

    Quantitative differences in the deposition of βA4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

    Gentleman, S. M., Allsop, D., Bruton, C. J., Jagoe, R., Polak, J. M. & Roberts, G. W., 17/02/1992, In : Neuroscience Letters. 136, 1, p. 27-30 4 p.

    Research output: Contribution to journalJournal article

  21. Published

    Alzheimer amyloid β/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 14/06/1991, In : Brain Research. 551, 1-2, p. 1-9 9 p.

    Research output: Contribution to journalJournal article

  22. Published

    A monoclonal antibody to common acute lymphoblastic leukemia antigen (neutral endopeptidase) immunostains senile plaques in the brains of patients with Alzheimer's disease

    Sato, M., Ikeda, K., Haga, S., Allsop, D. & Ishii, T., 2/01/1991, In : Neuroscience Letters. 121, 1-2, p. 271-273 3 p.

    Research output: Contribution to journalJournal article

  23. Published

    Amyloid deposition as the central event in the aetiology of Alzheimer's disease

    Hardy, J. & Allsop, D., 1991, In : Trends in Pharmacological Sciences. 12, 10, p. 383-388 6 p.

    Research output: Contribution to journalJournal article

  24. Published

    Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 12/1990, In : Human Pathology. 21, 12, p. 1221-1226 6 p.

    Research output: Contribution to journalJournal article

  25. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

    Allsop, D., Haga, S. I., Haga, C., Ikeda, S. I., Mann, D. M. & Ishii, T., 12/1990, In : Neuropathology and Applied Neurobiology. 15, 6, p. 531-542 12 p.

    Research output: Contribution to journalJournal article

  26. Published

    The occult aftermath of boxing

    Roberts, G. W., Allsop, D. & Bruton, C., 05/1990, In : Journal of Neurology, Neurosurgery and Psychiatry. 53, 5, p. 373-378 6 p.

    Research output: Contribution to journalJournal article

  27. Published

    Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to β protein and cystatin C

    Maruyama, K., Ikeda, S., Ishihara, T., Allsop, D. & Yanagisawa, N., 03/1990, In : Stroke; a journal of cerebral circulation. 21, 3, p. 397-403 7 p.

    Research output: Contribution to journalJournal article

  28. Published

    Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage

    Ohshima, T., Endo, T., Nukui, H., Ikeda, S., Allsop, D. & Onaya, T., 03/1990, In : Stroke; a journal of cerebral circulation. 21, 3, p. 480-483 4 p.

    Research output: Contribution to journalJournal article

  29. Published

    Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid β-protein of Alzheimer's disease

    Allsop, D., Haga, S., Bruton, C., Ishii, T. & Roberts, G. W., 02/1990, In : American Journal of Pathology. 136, 2, p. 255-260 6 p.

    Research output: Contribution to journalJournal article

  30. Published

    The nomenclature of the cerebral amyloid fibril protein in Alzheimer's disease

    Allsop, D., 01/1990, In : Neurobiology of Aging. 11, 1, p. 63-64 2 p.

    Research output: Contribution to journalJournal article

  31. Published

    A possible unified nomenclature for Alzheimer amyloid protein, precursors and gene

    Allsop, D., 01/1990, In : Neurobiology of Aging. 11, 1, p. 69 1 p.

    Research output: Contribution to journalJournal article

  32. Published

    Evidence of amyloid β-protein immunoreactive early plaque lesions in Down's syndrome brains

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 1989, In : Laboratory Investigation. 61, 1, p. 133-137 5 p.

    Research output: Contribution to journalJournal article

  33. Published

    Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases: an immunohistochemical study using amyloid β-protein antibody

    Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In : Laboratory Investigation. 60, 1, p. 113-122 10 p.

    Research output: Contribution to journalJournal article

  34. Published

    A study of the morphology and distribution of amyloid β protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome

    Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In : Progress in Clinical and Biological Research. 317, p. 313-323 11 p.

    Research output: Contribution to journalJournal article

  35. Published

    Evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. & Glenner, G. G., 1989, In : Progress in Clinical and Biological Research. 317, p. 893-902 10 p.

    Research output: Contribution to journalJournal article

  36. Published

    A demonstration of the advantages of immunostaining in the quantification of amyloid plaque deposits

    Gentleman, S. M., Bruton, C., Allsop, D., Lewis, S. J., Polak, J. M. & Roberts, G. W., 1989, In : Histochemistry. 92, 4, p. 355-358 4 p.

    Research output: Contribution to journalJournal article

  37. Published

    Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein

    Allsop, D., Ikeda, S., Bruce, M. & Glenner, G. G., 5/10/1988, In : Neuroscience Letters. 92, 2, p. 234-239 6 p.

    Research output: Contribution to journalJournal article

  38. Published

    CNS amyloid proteins in neurodegenerative diseases

    Roberts, G. W., Lofthouse, R., Allsop, D., Landon, M., Kidd, M., Prusiner, S. B. & Crow, T. J., 1988, In : Neurology. 38, 10, p. 1534-40 7 p.

    Research output: Contribution to journalJournal article

  39. Published

    Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer disease

    Allsop, D., Wong, C. W., Ikeda, S., Landon, M., Kidd, M. & Glenner, G. G., 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 8, p. 2790-2794 5 p.

    Research output: Contribution to journalJournal article

  40. Published

    Immunogold labeling of cerebrovascular and neuritic plaque amyloid fibrils in Alzheimer's disease with an anti-β protein monoclonal antibody

    Ikeda, S., Wong, C. W., Allsop, D., Landon, M., Kidd, M. & Glenner, G. G., 1987, In : Laboratory Investigation. 57, 4, p. 446-9 4 p.

    Research output: Contribution to journalJournal article

  41. Published

    Isolated senile plaque cores in Alzheimer's disease and Down's syndrome show differences in morphology

    Allsop, D., Kidd, M., Landon, M. & Tomlinson, A., 1986, In : Journal of Neurology, Neurosurgery and Psychiatry. 49, 8, p. 886-892 7 p.

    Research output: Contribution to journalJournal article

  42. Published

    Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

    Allsop, D., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Gardner, A., 1986, In : Neuroscience Letters. 68, 2, p. 252-6 5 p.

    Research output: Contribution to journalJournal article

  43. Published

    Senile plaque amyloid, paired helical filaments, and cerebrovascular amyloid in Alzheimer's disease are all deposits of the same protein

    Kidd, M., Allsop, D. & Landon, M., 1985, In : Lancet. 1, 8423, p. 278

    Research output: Contribution to journalJournal article

  44. Published

    The isolation and amino acid composition of senile plaque core protein

    Allsop, D., Landon, M. & Kidd, M., 1983, In : Experimental Brain Research. 259, 2, p. 348-52 5 p.

    Research output: Contribution to journalJournal article

  45. Letter
  46. Published

    β(A4)-amyloid protein and parkinsonian dementia complex of Guam

    Gentleman, S. M., Perl, D., Allsop, D., Clinton, J., Royston, M. C. & Roberts, G. W., 5/01/1991, In : Lancet. 337, 8732, p. 55-56 2 p.

    Research output: Contribution to journalLetter

  47. Literature review
  48. Published

    Amyloid β-peptide and Alzheimer's disease

    Allsop, D. & Mayes, J., 18/08/2014, In : Essays in Biochemistry. 56, p. 99-110 12 p., 7.

    Research output: Contribution to journalLiterature review

  49. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In : Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to journalLiterature review

  50. Editorial
  51. Published

    Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial)

    Foulds, P., Mann, D. & Allsop, D., 2012, In : Expert Review of Molecular Diagnostics. 12, 2, p. 115-117 3 p.

    Research output: Contribution to journalEditorial

  52. Meeting abstract
  53. Published

    Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease

    Allsop, D., Aggidis, A., Fullwood, N. J., Taylor, M. N., Foulds, P., Vincent, S. & Dale, M., 2018, In : Journal of Prevention of Alzheimer's Disease. 5, Suppl 1, p. S15-S16 2 p.

    Research output: Contribution to journalMeeting abstract

  54. Published

    A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation

    Allsop, D., Taylor, M. N., Fullwood, N. J., Michael, M., Aggidis, A., Vincent, S. & Dale, M., 1/11/2017, In : Journal of Prevention of Alzheimer's Disease. 4, 4, p. 385-386 2 p.

    Research output: Contribution to journalMeeting abstract

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