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Professor David Allsop

Formerly at Lancaster University

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  1. Published

    Donepezil for severe Alzheimer's disease.

    Allsop, D., Martin, F., Moore, S. & Fullwood, N. J., 29/07/2006, In: Lancet. 368, 9533, p. 361-362 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran and 2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran do not act as surfactants or micelles when inhibiting the aggregation of β-amyloid peptide.

    Allsop, D., Gibson, G., Martin, I. K., Moore, S., Turnbull, S. & Twyman, L. J., 01/2001, In: Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 255-257 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

    Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Introduction to Alzheimer's disease.

    Allsop, D., 2000, Alzheimer's disease : methods and protocols. Hooper, N. (ed.). Totawa, New Jersey: Humana Press, p. 1-21 21 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  5. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In: Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Amyloidosis in Alzheimer's disease

    Allsop, D. & Williams, C. H., 1994, In: Biochemical Society Transactions. 22, 1, p. 171-175 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Alzheimer amyloid β/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 14/06/1991, In: Brain Research. 551, 1-2, p. 1-9 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid β-protein of Alzheimer's disease

    Allsop, D., Haga, S., Bruton, C., Ishii, T. & Roberts, G. W., 02/1990, In: American Journal of Pathology. 136, 2, p. 255-260 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    The nomenclature of the cerebral amyloid fibril protein in Alzheimer's disease

    Allsop, D., 01/1990, In: Neurobiology of Aging. 11, 1, p. 63-64 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    A possible unified nomenclature for Alzheimer amyloid protein, precursors and gene

    Allsop, D., 01/1990, In: Neurobiology of Aging. 11, 1, p. 69 1 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

    Allsop, D., Haga, S. I., Haga, C., Ikeda, S. I., Mann, D. M. & Ishii, T., 12/1990, In: Neuropathology and Applied Neurobiology. 15, 6, p. 531-542 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. & Glenner, G. G., 1989, In: Progress in Clinical and Biological Research. 317, p. 893-902 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein

    Allsop, D., Ikeda, S., Bruce, M. & Glenner, G. G., 5/10/1988, In: Neuroscience Letters. 92, 2, p. 234-239 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer disease

    Allsop, D., Wong, C. W., Ikeda, S., Landon, M., Kidd, M. & Glenner, G. G., 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 8, p. 2790-2794 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Isolated senile plaque cores in Alzheimer's disease and Down's syndrome show differences in morphology

    Allsop, D., Kidd, M., Landon, M. & Tomlinson, A., 1986, In: Journal of Neurology, Neurosurgery and Psychiatry. 49, 8, p. 886-892 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

    Allsop, D., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Gardner, A., 1986, In: Neuroscience Letters. 68, 2, p. 252-6 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    The isolation and amino acid composition of senile plaque core protein

    Allsop, D., Landon, M. & Kidd, M., 1983, In: Experimental Brain Research. 259, 2, p. 348-52 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    The effect of a high non-permissive temperature on chloroplast development in barley

    Allsop, D., Atkinson, Y. E. & Bradbeer, J. W., 1981, Photosynthesis V: chloroplast development. Akoyunoglou, G. (ed.). Philadelphia: Balaban International Science Services, p. 787-795 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  20. Published

    Biochemistry of cerebral amyloid in Alzheimer’s disease, the unconventional slow virus diseases, and Icelandic cerebrovascular amyloidosis

    Allsop, D., 1986, Amyloidosis. Marrink, J. & van Rijswijk, M. H. (eds.). Dordrecht: Martinus Nijhoff Publishers/ Brill Academic, p. 243-253 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  21. Published

    Antibody staining of cerebral amyloid in Alzheimer’s disease, Down’s syndrome, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome

    Allsop, D., Roberts, G. W., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Crowe, T. J., 1987, Advancing Frontiers in Alzheimer’s Disease Research. Glenner, G. G. & Wurtman, J. (eds.). Austin: University of Texas Press, p. 137-153 17 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  22. Published

    Evidence for the derivation of a peptide ligand from the amyloid β protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. I. & Glenner, G. G., 1989, Alzheimer's disease and related disorders: proceedings of the First International Conference on Alzheimer's Disease and Related Disorders, held in Las Vegas, Nevada, September 5-9, 1988. Iqbal, K., Wisniewski, H. M. & Winblad, B. (eds.). New York: Alan R. Liss, p. 893-902 10 p. (Progress in clinical and biological research; vol. 317).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  23. Published

    Evidence for a neuronal origin of senile plaques in Down's syndrome brains

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Basic and therapeutic aspects of Alzheimer's and Parkinson's diseases. Nagatsu, T. (ed.). New York: Plenum Press, Vol. 1. p. 83-86 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  24. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons: evidence for a neuronal origin of senile plaque amyloid

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Molecular biology and genetics of Alzheimer disease. Miyatake, T., Selkoe, D. J. & Ihara, Y. (eds.). Amsterdam: Elsevier, p. 95-104 10 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  25. Published

    Studies on the binding and proteolytic cleavage of an Alzheimer amyloid synthetic peptide

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Frontiers of Alzheimer research. Ishii, T., Allsop, D. & Selkoe, D. J. (eds.). Amsterdam: Elsevier, p. 171-183 13 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  26. Published

    High affinity amyloid peptide β/A4 binding sites and a putative "APP secretase" in rat brain

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Proceedings of the XIth International Congress of Neuropathology: The Japanese Society of Neuropathology. Sasaki, Japan, p. 119-127 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  27. Published

    Secretory derivatives of Alzheimer amyloid precursor protein in cerebrospinal fluid and brain: only Kunitz-containing forms show amyloid immunoreactivity

    Allsop, D., Kennedy, H. E. & Kametani, F., 1993, Alzheimer's disease: advances in clinical and basic research. Corain, B., Iqbal, K., Nicolini, M., Winblad, B., Wisniewski, H. M. & Zatta, P. (eds.). Chichester: Wiley, p. 421-429 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  28. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Allsop, D., Clements, A., Kennedy, H. E., Walsh, D. M. & Williams, C. H., 1994, Amyloid precursor protein in development, ageing and Alzheimer's disease. Berlin: Springer Verlag, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  29. Published

    Studies on inhibition of β-amyloid formation in APP-751-transfected IMR-32 cells, and SPA4CT-transfected SHSY5Y cells

    Allsop, D., Christie, G., Gray, C., Holmes, S., Markwell, R., Owen, D., Smith, L., Wadsworth, H., Ward, R. V., Hartmann, T., Lichtenthaler, S. F., Evin, G., Fuller, S., Tanner, J., Masters, C. L., Beyreuther, K. & Roberts, G. W., 1997, Alzheimer's disease: biology, diagnosis and therapeutics. Iqbal, K., Winblad, B., Nishimura, T., Takeda, M. & Wisniewski, H. M. (eds.). New York: Wiley, p. 717-727 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  30. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In: Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

  31. Published

    Amyloid β-peptide and Alzheimer's disease

    Allsop, D. & Mayes, J., 18/08/2014, In: Essays in Biochemistry. 56, p. 99-110 12 p., 7.

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

  32. Published

    A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation

    Allsop, D., Taylor, M. N., Fullwood, N. J., Michael, M., Aggidis, A., Vincent, S. & Dale, M., 1/11/2017, In: Journal of Prevention of Alzheimer's Disease. 4, 4, p. 385-386 2 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

  33. Published

    Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease

    Allsop, D., Aggidis, A., Fullwood, N. J., Taylor, M. N., Foulds, P., Vincent, S. & Dale, M., 2018, In: Journal of Prevention of Alzheimer's Disease. 5, Suppl 1, p. S15-S16 2 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract

  34. Published

    Chloroplast development in normal and mutant lines of barley

    Atkinson, Y. E., Allsop, D. & Bradbeer, J. W., 1981, Photosynthesis V: chloroplast development. Akoyunoglou, G. (ed.). Philadelphia: Balaban International Science Services, p. 797-808 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  35. Published

    Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide

    Austen, B. M., Paleologou, K. E., Ali, S. A. E., Qureshi, M. M., Allsop, D. & El-Agnaf, O. M. A., 2008, In: Biochemistry. 47, 7, p. 1984-1992 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  36. Published

    Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

    Castelletto, V., Ryumin, P., Cramer, R., Hamley, I., Taylor, M. N., Allsop, D., Reza, M., Ruokolainen, J., Arnold, T., Hermida-Merino, D., Garcia, C. I., Leal, M. C. & Castaño, E., 8/03/2017, In: Scientific Reports. 7, 12 p., 43637.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  37. Published

    Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

    Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A., & 4 othersGardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In: Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  38. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In: Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  39. Published

    Aggregation of Alzheimer's peptides

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In: Biochemical Society Transactions. 22, 1, p. 16S 1 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  40. Published

    Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In: Neuroscience Letters. 161, 1, p. 17-20 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  41. Published

    TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome: association with age, hippocampal sclerosis and clinical phenotype

    Davidson, Y. S., Raby, S., Foulds, P., Robinson, A., Thompson, J. C., Sikkink, S., Yusuf, I., Amin, H., Duplessis, D., Troakes, C., Al-Sarraj, S., Sloan, C., Esiri, M. M., Prasher, V. P., Allsop, D., Neary, D., Pickering-Brown, S. M., Snowden, J. S. & Mann, D. M. A., 12/2011, In: Acta Neuropathologica. 122, 6, p. 703-713 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  42. Published

    Alzheimer's disease diagnosis by blood plasma molecular fluorescence spectroscopy (EEM)

    Dos Santos, R. F., Paraskevaidi, M., Mann, D. M. A., Allsop, D., Santos, M. C. D., Morais, C. L. M. & Lima, K. M. G., 28/09/2022, In: Scientific Reports. 12, 1, 13 p., 16199.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  43. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In: Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  44. Published

    Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Curran, M. D., Gibson, M. J., Court, J. A., Schlossmacher, M. G. & Allsop, D., 2006, In: FASEB Journal. 20, 3, p. 419-425 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  45. Published

    A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.

    El-Agnaf, O. M. A., Paleologou, K. E., Greer, B., Abogrein, A. M., King, J., Salem, S. A., Fullwood, N. J., Benson, F. E., Hewitt, R., Ford, K. J., Martin, F., Harriott, P., Cookson, M. R. & Allsop, D., 08/2004, In: FASEB Journal. 18, 11, p. 1315-1317 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  46. Published

    α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma.

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Cooper, L. J., Fullwood, N. J., Gibson, M. J., Curran, M. D., Court, J. A., Mann, D. M. A., Ikeda, S-I., Cookson, M. R., Hardy, J. & Allsop, D., 10/2003, In: FASEB Journal. 17, 13, p. 1945-1947 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  47. Published

    Soluble oligomers for the diagnosis of neurodegenerative diseases.

    El-Agnaf, O. M. A., Walsh, D. M. & Allsop, D., 08/2003, In: Lancet Neurology. 2, 8, p. 461-462 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  48. Published

    Characterization of an α-secretase candidate from human brain using a new western blot assay

    Evin, G., Reed, G., Tanner, J. E., Li, Q. X., Culvenor, J. G., Fuller, S. J., Wadsworth, H., Allsop, D., Ward, R. V., Karran, E. H., Gray, C. W., Hartmann, T., Lichtenthaler, S. F., Weidemann, A., Beyreuther, K. & Masters, C. L., 1999, Alzheimer's disease and related disorders. Iqbal, K., Swaab, D. F., Winblad, B. & Wisniewski, H. M. (eds.). Wiley, p. 411-418 8 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  49. Published

    Parkinson disease: progress towards a molecular biomarker for Parkinson disease

    Foulds, P., Mann, D. M. A., Mitchell, J. D. & Allsop, D., 07/2010, In: Nature Reviews Neurology. 6, 7, p. 359-361 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  50. Published

    Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

    Foulds, P., Davidson, Y., Mishra, M., Hobson, D. J., Humphreys, K. M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E. H., Benson, F. E., Allsop, D. & Mann, D. M. A., 2009, In: Acta Neuropathologica. 118, 5, p. 647-658 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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