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Professor Ian Nieduszynski

Emeritus

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  1. 2011
  2. Published

    Characterisation of oligosaccharides from the chondroitin/dermatan sulphates: 1H and 13C NMR studies of oligosaccharides generated by nitrous acid depolymerisation

    Lauder, R. M., Huckerby, T., Nieduszynski, I. & Sadler, I. H., 18/10/2011, In: Carbohydrate Research. 346, 14, p. 2222-2227 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Lectin affinity chromatography of articular cartilage fibromodulin: some molecules have keratan sulphate chains exclusively capped by α(2-3)-linked sialic acid.

    Lauder, R. M., Huckerby, T. & Nieduszynski, I., 10/2011, In: Glycoconjugate Journal. 28, 7, p. 453–461 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. 2006
  5. Published

    The role of dermatopontin in the stromal organisation of the cornea.

    Cooper, L. J., Bentley, A. J., Nieduszynski, I. A., Talabani, S., Thomson, A., Utani, A., Shinkai, H., Fullwood, N. J. & Brown, G. M., 08/2006, In: Investigative Ophthalmology and Visual Science. 47, 8, p. 3303-3310 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. 2005
  7. Published

    Characterization of oligosaccharides from the chondroitin/dermatan sulfates. 1H-NMR and 13C-NMR studies of reduced trisaccharides and hexasaccharides.

    Huckerby, T. N., Nieduszynski, I. A., Giannopoulos, M., Weeks, S. D., Sadler, I. H. & Lauder, R. M., 12/2005, In: FEBS Journal. 272, 24, p. 6276-6286 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. 2004
  9. Published

    An ultrastructural investigation of dermato-pontin-knockout mouse corneas

    Cooper, L. J., Bentley, A. J., Nieduszynski, I. A., Fullwood, N. J., Ellis, T. S., Thomson, A., Utani, A., Sinkai, H. & Brown, G. M., 08/2004, In: International Journal of Experimental Pathology. 85, 4, p. A59-A60 2 p.

    Research output: Contribution to Journal/Magazine › Special issue › peer-review

  10. 2003
  11. Published

    Recent studies on the chondroitin sulfate/dermatan sulfate polymer systems using NMR spectroscopy.

    Huckerby, T. N., Lauder, B. & Nieduszynski, I., 03/2003, In: Abstracts of Papers of the American Chemical Society. 225, p. U653-U653 1 p.

    Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

  12. Published

    Recent studies on the chondroitin sulfate/dermatan sulfate polymer systems using NMR spectroscopy

    Huckerby, T. N., Lauder, R. M. & Nieduszynski, I. A., 2003, In: ACS Polymer Preprints. 44, 1, p. 328-329 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. 2002
  14. Published

    Keratan sulfates : structural investigations using NMR spectroscopy.

    Huckerby, T. N., Brown, G. M., Lauder, R. M. & Nieduszynski, I. A., 2002, NMR Spectroscopy of Polymers in Solution and in the Solid State (Chapter 22). Vol. 834. p. 289-297 9 p. (ACS Symposium Series).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed)

  15. 2001
  16. Published

    Age-related changes in the sulphation of the chondroitin sulphate linkage region from human articular cartilage aggrecan.

    Lauder, R. M., Huckerby, T. N., Brown, G., Bayliss, M. T. & Nieduszynski, I. A., 1/09/2001, In: Biochemical Journal. 358, 2, p. 523-528 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Localization of TRAMP (Tyrosine-Rich Acidic Matrix Protein)

    Bolden, K., Fullwood, N., Nieduszynski, I. & Bairaktaris, G., 8/03/2001, In: FASEB Journal. 15, 5, p. A893-A893 1 p.

    Research output: Contribution to Journal/Magazine › Book/Film/Article review › peer-review

  18. Published

    Characterisation of oligosaccharides from the chondroitin sulfates. 1H-NMR and 13C-NMR studies of reduced disaccharides and tetrasaccharides.

    Huckerby, T. N., Lauder, R. M., Brown, G. M., Nieduszynski, I. A., Anderson, K., Boocock, J., Sandall, P. L. & Weeks, S. D., 03/2001, In: European Journal of Biochemistry. 268, 5, p. 1181-1189 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Keratan sulfates : structural investigations using NMR spectroscopy.

    Huckerby, T. N., Brown, G. M., Lauder, R. M. & Nieduszynski, I. A., 2001, In: Abstracts of Papers of the American Chemical Society. 221, 2, p. 396

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Keratan sulfates : structural investigations using NMR spectroscopy.

    Huckerby, T. N., Brown, G. M., Lauder, R. M. & Nieduszynski, I. A., 2001, In: ACS Polymer Preprints. 42, 1, p. 78-79 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. 2000
  22. Published

    Increased incidence of unsulphated and 4-sulphated residues in the chondroitin sulphate linkage region observed by high-pH anion-exchange chromatography.

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 15/04/2000, In: Biochemical Journal. 347, 2, p. 339-348 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    A fingerprinting method for chondroitin/dermatan sulfate and hyaluronan oligosaccharides.

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 04/2000, In: Glycobiology. 10, 4, p. 393-401 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Ultrastructural localization of sulfated and unsulfated keratan sulfate in normal and macular corneal dystrophy type I.

    Lewis, D., Davies, Y., Nieduszynski, I. A., Lawrence, F., Quantock, A. J., Bonshek, R. & Fullwood, N. J., 03/2000, In: Glycobiology. 10, 3, p. 305-312 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Structure and function of corneal keratan sulfates.

    Nieduszynski, I. A., Ellis, T. S., Brown, G. M. & Huckerby, T. N., 2000, Abstracts of papers of the American Chemical Society. Vol. 219.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  26. 1999
  27. Published

    Characterisation of an octasaccharide chondroitin sulphate linkage region fragment

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 1/12/1999, In: Carbohydrate Letters. 3, 5, p. 381-388 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    600 MHz NMR studies of human articular cartilage keratan sulfates.

    Huckerby, T. N., Nieduszynski, I. A., Bayliss, M. T. & Brown, G. M., 12/1999, In: European Journal of Biochemistry. 266, 3, p. 1174-1183 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  29. Published

    Ultrastructural localisation of sulphated and unsulphated keratan sulphate in normal cornea and macular corneal dystrophy type I

    Lewis, D., Fullwood, N. J., Davies, Y., Nieduszynski, I. A., Quantock, A. J. & Bonshek, R., 15/03/1999, In: Investigative Ophthalmology and Visual Science. 40, 4, p. S330-S330 1 p.

    Research output: Contribution to Journal/Magazine › Special issue › peer-review

  30. Published

    An improved method for the structural profiling of keratan sulphates : analysis of keratan suplhates from brain and ovarian tumours.

    Whitham, K. M., Hadley, J. L., Morris, H. G., Andrew, S. M., Nieduszynski, I. A. & Brown, G. M., 03/1999, In: Glycobiology. 9, 3, p. 285-291 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  31. Published

    Proteoglycans on normal and migrating human corneal endothelium.

    Davies, Y., Lewis, D., Fullwood, N. J., Nieduszynski, I. A., Marcyniuk, B., Albon, J. & Tullo, A., 03/1999, In: Experimental Eye Research. 68, 3, p. 303-311 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  32. Published

    Isolation and identification of an octasaccharide chondroitin sulphate linkage region fragment.

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 1999, In: Carbohydrate Letters. 3, 5, p. 381-388 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  33. 1998
  34. Published

    Human aggrecan keratan sulfate undergoes structural changes during adolescent development

    Brown, G., Huckerby, T. N., Bayliss, M. T. & Nieduszynski, I. A., 9/10/1998, In: Journal of Biological Chemistry. 273, 41, p. 26408-26414 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  35. Published

    An ultrastructural investigation into proteoglycan distribution in human corneas

    Bairaktaris, G., Lewis, D., Fullwood, N. J., Nieduszynski, I. A., Marcyniuk, B., Quantock, A. J. & Ridgway, A. E. A., 07/1998, In: Cornea. 17, 4, p. 396-402 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  36. Published

    13C-NMR spectroscopy of keratan sulphates--assignments for five sialylated pentasaccharides derived from the non-reducing chain termini of bovine articular cartilage keratan sulphate by keratanase II digestion

    Huckerby, T. N., Brown, G. & Nieduszynski, I. A., 02/1998, In: European Journal of Biochemistry. 251, 3, p. 991-997 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  37. Published

    Age-related changes in the structure of the keratan sulphate chains attached to fibromodulin isolated from articular cartilage.

    Lauder, R. M., Huckerby, T. N., Nieduszynski, I. A. & Plaas, A. H., 1998, In: Biochemical Journal. 330 , p. 753-757 5 p.

    Research output: Contribution to Journal/Magazine › Journal article

  38. Published

    Structure determination for octasaccharides derived from the carbohydrate-protein linkage region of chondroitin sulphate chains in the proteoglycan aggrecan from bovine articular cartilage.

    Huckerby, T. N., Lauder, R. M. & Nieduszynski, I. A., 1998, In: European Journal of Biochemistry. 258, 2, p. 669-676 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  39. 1997
  40. Published

    Human corneal keratan sulfates

    Tai, G. H., Nieduszynski, I. A., Fullwood, N. J. & Huckerby, T. N., 7/11/1997, In: Journal of Biological Chemistry. 272, 45, p. 28227-28231 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  41. Published

    The structure of the keratan sulphate chains attached to fibromodulin from human articular cartilage

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 08/1997, In: Glycoconjugate Journal. 14, 5, p. 651-660 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  42. Published

    Keratan sulphate in the trabecular meshwork and cornea

    Davis, Y., Fullwood, N. J., Marcyniuk, B., Bonshek, R., Tullo, A. & Nieduszynski, I. A., 07/1997, In: Current Eye Research. 16, 7, p. 677-686 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  43. 1996
  44. Published

    Characterisation of a nonreducing terminal fragment from bovine articular-cartilage keratan sulfates containing alpha(2-3)-linked sialic-acid and alpha(1-3)-linked fucose.

    Brown, G. M., Huckerby, T. N., Abram, B. L. & Nieduszynski, I. A., 10/1996, In: Biochemical Journal. 319, 1, p. 137-141 5 p.

    Research output: Contribution to Journal/Magazine › Journal article

  45. Published

    Multiple Non-reducing Chain Termini Isolated from Bovine Corneal Keratan Sulfates.

    Tai, G-H., Huckerby, T. N. & Nieduszynski, I. A., 09/1996, In: Journal of Biological Chemistry. 271, 38, p. 23535-23546 12 p.

    Research output: Contribution to Journal/Magazine › Journal article

  46. Published

    Cell surface-associated keratan sulfate on normal and migrating corneal endothelium.

    Fullwood, N. J., Davies, Y., Nieduszynski, I. A., Marcyniuk, B., Ridgway, A. E. A. & Quantock, A. J., 06/1996, In: Investigative Ophthalmology and Visual Science. 37, 7, p. 1256-1270 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  47. Published

    Changes in cell surface glycosaminoglycans during endothelial cell migration

    Fullwood, N. J., Davies, Y., Nieduszynski, I. A., Marcyniuk, B., Ridgway, A. E. A. & Quantock, A., 15/02/1996, In: Investigative Ophthalmology and Visual Science. 37, 3, p. 1093-1093 1 p.

    Research output: Contribution to Journal/Magazine › Book/Film/Article review › peer-review

  48. Published

    The structure of keratan sulphate chains attached to fibromodulin from bovine articular cartilage.

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 1996, In: European Journal of Biochemistry. 242, 2, p. 402-409 8 p.

    Research output: Contribution to Journal/Magazine › Journal article

  49. 1995
  50. Published

    THE STRUCTURE OF THE KERATAN SULFATE CHAINS ATTACHED TO FIBROMODULIN ISOLATED FROM BOVINE TRACHEAL CARTILAGE - OLIGOSACCHARIDES GENERATED BY KERATANASE-II DIGESTION

    LAUDER, R. M., HUCKERBY, T. N. & NIEDUSZYNSKI, I. A., 10/1995, In: Glycoconjugate Journal. 12, 5, p. 651-659 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  51. Published

    Keratanase digestion of keratan sulphates: characterisation of large oligosaccharides from the N-acetyllactosamine repeat sequence and from the non-reducing terminal chain caps.

    Huckerby, T. N., Dickenson, J. M., Brown, G. M. & Nieduszynski, I. A., 11/05/1995, In: Biochimica et Biophysica Acta (BBA) - General Subjects. 1244, 1, p. 17-29 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  52. Published

    <sup>13</sup>C-NMR spectroscopy of keratan sulphates

    Huckerby, T. N., Brown, G. M. & Nieduszynski, I. A., 1995, In: European Journal of Biochemistry. 231, 3, p. 779-783 5 p.

    Research output: Contribution to Journal/Magazine › Journal article

  53. Published

    Skeletal keratan sulphate structural analysis using keratanase II digestion followed by high-performance anion-exchange chromatography.

    Brown, G. M., Nieduszynski, I. A., Morris, H. G., Abram, B. L., Huckerby, T. N. & Block, J. A., 1995, In: Glycobiology. 5, 3, p. 311-317 7 p.

    Research output: Contribution to Journal/Magazine › Journal article

  54. Published

    Spectroscopic characterisation of disaccharides derived from keratan sulfates.

    Huckerby, T. N., Brown, G. M., Dickenson, J. M. & Nieduszynski, I. A., 1995, In: European Journal of Biochemistry. 229, 1, p. 119-131 13 p.

    Research output: Contribution to Journal/Magazine › Journal article

  55. 1994
  56. Published

    The structure of the keratan sulphate attached to fibromodulin isolated from bovine tracheal cartilage, Oligosaccharides isolated following keratanase digestion.

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 1/09/1994, In: Biochemical Journal. 302, 2, p. 417-423 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  57. Published

    600 MHz 1H NMR study of a fucose-containing heptasaccharide derived from a keratanase digestion of bovine articular cartilage keratan sulphate.

    Tai, G-H., Huckerby, T. N. & Nieduszynski, I. A., 4/03/1994, In: Carbohydrate Research. 255, p. 303-309 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  58. Published

    Isolation and extractability of fibromodulin.

    Lauder, R. M., Morris, H. G., Nieduszynski, I. A. & Huckerby, T. N., 1994, In: Bone. 15, 1, p. 128-129 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  59. Published

    Oligosaccharides Derived by Keratanase II Digestion of Bovine Articular Cartilage Keratan Sulphates.

    Brown, G., Huckerby, T. N. & Nieduszynski, I. A., 1994, In: European Journal of Biochemistry. 224, 2, p. 281-308 28 p.

    Research output: Contribution to Journal/Magazine › Journal article

  60. Published

    Oligosaccharides Derived from Bovine Articular Cartilage Keratan Sulfates after Keratanase II Digestion: Implications for Keratan Sulfate Structural Fingerprinting.

    Brown, G. M., Huckerby, T. N., Morris, H. G., Abram, B. L. & Nieduszynski, I. A., 1994, In: Biochemistry. 33, 16, p. 4836-4846 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  61. Published

    Structure of the keratan sulphate chains attached to fibromodulin isolated from bovine tracheal cartilage. Oligosaccharides generated by keratanase digestion.

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 1994, In: Biochemical Journal. 302, p. 417-423 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  62. 1993
  63. Published

    13C NMR spectroscopy of keratan sulphates : assignments for the reduced form of a repeat unit tetrasaccharide derived from keratan sulphate by a keratanase digestion and partial assignments for two fucosylated pentasaccharides.

    Huckerby, T., Dickerson, J., Tai, G. H., Lauder, R., Brown, G. & Nieduszynski, I., 1993, In: Magnetic Resonance in Chemistry. 31, 4, p. 394-398 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  64. Published

    N.m.r. spectroscopic studies of fucose-containing oligosaccharides derived from keratanase digestion of articular cartilage keratan sulphates. Influence of fucose residues on keratanase cleavage.

    Tai, G-H., Huckerby, T. N. & Nieduszynski, I. A., 1993, In: Biochemical Journal. 291, p. 889-894 6 p.

    Research output: Contribution to Journal/Magazine › Journal article

  65. Published

    The structure of keratan sulphate attached to fibromodulin from bovine tracheal cartilage.

    Lauder, R. M., Huckerby, T. N. & Nieduszynski, I. A., 1993, In: International Journal of Experimental Pathology. 74, 4, p. A9-A10 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  66. 1992
  67. Published

    Characterization of oligosaccharides from the non-reducing termini of keratan sulphate chains.

    Huckerby, T. N., Dickenson, J. M. & Nieduszynski, I. A., 12/1992, In: Magnetic Resonance in Chemistry. 30, 13, p. S134-S141

    Research output: Contribution to Journal/Magazine › Journal article

  68. Published

    A sub-population of keratan sulphates derived from bovine articular cartilage is capped with alpha(2-6)-linked N-acetylneuraminic acid residues. Affinity chromatography using immobilized Sambucus nigra lectin and characterization using 1H n.m.r. spectroscopy

    Tai, G. H., Morris, H. G., Brown, G. M., Huckerby, T. N. & Nieduszynski, I. A., 1992, In: Biochemical Journal. 286 , 1, p. 231-234 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  69. Published

    Degradation of articular cartilage keratan sulphates using hydrazinolysis and nitrous acid. Environment of fucose residues.

    Brown, G., Huckerby, T. N., Morris, H. G. & Nieduszynski, I. A., 1992, In: Biochemical Journal. 286, 1, p. 235-241 7 p.

    Research output: Contribution to Journal/Magazine › Journal article

  70. Published

    Skeletal keratan sulphate chains isolated from bovine intervertebral disc may terminate in alpha(2----6)-linked N-acetylneuraminic acid.

    Dickenson, J. M., Huckerby, T. N. & Nieduszynski, I. A., 1992, In: Biochemical Journal. 282, 1, p. 267-271 5 p.

    Research output: Contribution to Journal/Magazine › Journal article

  71. 1991
  72. Published

    A full assignment of proton resonances for an alpha(1-3)-linked fucose residue in keratan sulphate from bovine articular cartilage

    Huckerby, T. N., Nieduszynski, I. A., Brown, G. M. & Cockin, G. H., 02/1991, In: Glycoconjugate Journal. 8, 1, p. 39-44 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  73. Published

    Fucose content of keratan sulphates from bovine articular cartilage

    Tai, G. H., Brown, G. M., Morris, H. G., Huckerby, T. N. & Nieduszynski, I. A., 1991, In: Biochemical Journal. 273, 2, p. 307-310 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  74. 1990
  75. Published

    Structural aspects of skeletal keratan sulphates

    Nieduszynski, I. A., Huckerby, T. N., Dickenson, J. M., Brown, G. M., Tai, G. H. & Bayliss, M. T., 10/1990, In: Biochemical Society Transactions. 18, 5, p. 792-793 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  76. Published

    There are two major types of skeletal keratan sulphates

    Nieduszynski, I. A., Huckerby, T. N., Dickenson, J. M., Brown, G., Tai, G. H., Morris, H. G. & Eady, S., 1990, In: Biochemical Journal. 271, 1, p. 243-245 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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