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Research

Dr Karen Grant

Formerly at Lancaster University

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  1. 2014
  2. Unpublished

    Evaluation of the transferability of skills learnt using simulation into real life practice

    Horrocks, J. L., Curtis, F. & Grant, K., 2014, (Unpublished).

    Research output: Contribution to conference - Without ISBN/ISSN › Poster › peer-review

  3. 2012
  4. Published

    Proteomic insights into parasite biology

    Ginger, M. L., McKean, P. G., Burchmore, R. & Grant, K. M., 08/2012, In: Parasitology. 139, 9, p. 1101-1102 2 p.

    Research output: Contribution to Journal/Magazine › Journal article

  5. 2011
  6. Published

    High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase

    Walker, R. G., Thomson, G., Malone, K., Nowicki, M. W., Brown, E., Blake, D. G., Turner, N. J., Walkinshaw, M. D., Grant, K. & Mottram, J. C., 5/04/2011, In: PLoS Neglected Tropical Diseases. 5, 4, 11 p., e1033.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. 2010
  8. Published

    Recombinant Leishmania mexicana CRK3:CYCA has protein kinase activity in the absence of phosphorylation on the T-loop residue Thr178.

    Gomez, F. C., Ali, N. O. M., Brown, E., Walker, R. G., Grant, K. M. & Mottram, J. C., 06/2010, In: Molecular and Biochemical Parasitology. 171, 2, p. 89-96 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2009
  10. Published

    6-Br-5methylindirubin-3′oxime (5-Me-6-BIO) targeting the leishmanial glycogen synthase kinase-3 (GSK-3) short form affects cell-cycle progression and induces apoptosis-like death: Exploitation of GSK-3 for treating leishmaniasis

    Xingi, E., Smirlis, D., Myrianthopoulos, V., Prokopios, M., Grant, K., Meijer, L., Mikros, E., Skaltsounis, A-L. & Soteriadou, K., 10/2009, In: International Journal for Parasitology. 39, 12, p. 1289-1303 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro.

    Arambage, S. C., Grant, K. M., Pardo, I., Ranford-Cartwright, L. & Hurd, H., 15/07/2009, In: Parasites and Vectors. 2, 1, 16 p., 32.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Trypanosomatid protein kinases as potential drug targets.

    Wiese, M., Morris, A. & Grant, K. M., 2009, Antiparasitic and antibacterial drug discovery : from molecular targets to drug candidates.. Selzer, P. M. (ed.). Weinheim: Wiley-VCH, p. 227-247 21 p. (Drug Discovery in Infectious Diseases.).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  13. 2008
  14. Published

    Targeting the Cell Cycle in the Pursuit of Novel Chemotherapies against Parasitic Protozoa.

    Grant, K. M., 2008, In: Current Pharmaceutical Design. 14, 9, p. 917-924 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. 2006
  16. Published

    Apoptosis-like death as a feature of malaria infection in mosquitoes.

    Hurd, H., Grant, K. M. & Arambage, S. C., 03/2006, In: Parasitology. 132, Supple, p. S33-S47

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    The selective biological activity of indirubin-based inhibitors : applications in parasitology.

    Wells, C., McNae, I., Walkinshaw, M., Westwood, N. J. & Grant, K. M., 2006, Indirubin, the red shade of indigo. Meijer, L., Guyard, N., Skaltsounis, A. L. & Eisenbrand, G. (eds.). Roscoff, France: Life in Progress Editions, p. 259-267 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  18. 2004
  19. Published

    Inhibitors of Leishmania mexicana CRK3 Cyclin-Dependent Kinase: Chemical Library Screen and Antileishmanial Activity.

    Grant, K. M., Dunion, M. H., Yardley, V., Skaltsounis, A-L., Marko, D., Eisenbrand, G., Croft, S. L., Meijer, L. & Mottram, J. C., 08/2004, In: Antimicrobial Agents and Chemotherapy. 48, 8, p. 3033-3042 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. 2002
  21. Published

    Intracellular targets of paullones : identification by affinity chromatography using immobilized inhibitor.

    Knockaert, M., Wieking, K., Schmitt, S., Leost, M., Grant, K. M., Mottram, J. C., Kunick, C. & Meijer, L., 12/07/2002, In: Journal of Biological Chemistry. 277, 28, p. 25493-25501 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. 2001
  23. Published

    The CRK3 protein kinase is essential for cell cycle progression of Leishmania mexicana.

    Hassan, P., Fergusson, D., Grant, K. M. & Mottram, J. C., 6/04/2001, In: Molecular and Biochemical Parasitology. 113, 2, p. 189-198 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. 2000
  25. Published

    Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

    Knockaert, M., Gray, N., Damiens, E., Chang, Y-T., Grellier, P., Grant, K. M., Fergusson, D., Mottram, J. C., Soete, M., Dubremetz, J-F., Le Roch, K., Doerig, C., Schultz, P. G. & Meijer, L., 1/06/2000, In: Chemistry and Biology. 7, 6, p. 411-422 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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