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Dr Karen Wright

Senior Lecturer in Biomedicine

  1. 2023
  2. Published

    The enrichment of whey protein isolate hydrogels with Poly-γ-glutamic acid promotes the proliferation and osteogenic differentiation of pre-osteoblasts

    Baines, D., Platania, V., Tavernaraki, N., Parati, M., Wright, K., Radecka, I., Chatzinikolaidou, M. & Douglas, T., 23/12/2023, In: Gels. 10, 1, 18.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    The Enrichment of Whey Protein Isolate Hydrogels with Poly-γ-Glutamic Acid Promotes the Proliferation and Osteogenic Differentiation of Preosteoblasts

    Baines, D. K., Platania, V., Tavernaraki, N. N., Parati, M., Wright, K., Radecka, I., Chatzinikolaidou, M. & Douglas, T. E. L., 23/12/2023, In: Gels. 10, 1, p. 18

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Dehydration analysis of poly-ethylene glycol hydrogels with terahertz imaging

    Baines, D., Bassu, G., Wright, K., Douglas, T., Degl'Innocenti, R., Laurati, M. & Lin, H., 3/08/2023, Technical Digest Series: Optica Sensing Congress 2023 (AIS, FTS, HISE, Sensors, ES). Optica Publishing Group, paper JW2A.3

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  5. Published

    The emerging role of fatty acid binding protein 5 (FABP5) in cancers

    Warren, W. G., Osborn, M., Yates, A., Wright, K. & O'Sullivan, S. E., 31/07/2023, In: Drug Discovery Today. 28, 7, 15 p., 103628.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. 2022
  7. Forthcoming

    Cannabidiol (CBD) may influence substrate utilisation during and muscle recovery following damaging exercise

    Gaffney, C., Cunnington, J., Greathead, N., Rigby, E., Scott, D., Montemayor, M., Garvey, H. & Wright, K., 24/04/2022, (Accepted/In press).

    Research output: Contribution to conference - Without ISBN/ISSN Abstractpeer-review

  8. 2021
  9. Published

    Electrical Stimulation to Enhance Wound Healing

    Rajendran, S., Challen, K., Wright, K. & Hardy, J., 19/06/2021, In: Journal of Functional Biomaterials. 12, 2, 17 p., 40.

    Research output: Contribution to Journal/MagazineLiterature reviewpeer-review

  10. Published

    Potential for Chemistry in Multidisciplinary, Interdisciplinary, and Transdisciplinary Teaching Activities in Higher Education

    Hardy, J., Sdepanian, S., Stowell, A., Aljohani, A., Allen, M., Anwar, A., Barton, D., Baum, J., Bird, D., Blaney, A., Brewster, L., Cheneler, D., Efremova, O., Entwistle, M., Esfahani, R., Firlak, M., Foito, A., Forciniti, L., Geissler, S., Guo, F., & 19 othersHathout, R., Jiang, R., Kevin, P., Leese, D., Low, W. L., Mayes, S., Mozafari, M., Murphy, S., Nguyen, H., Ntola, C., Okafo, G., Partington, A., Prescott, T., Price, S., Soliman, S., Sutar, P., Townsend, D., Trotter, P. & Wright, K., 4/03/2021, In: Journal of Chemical Education. 98, 4, p. 1124–1145 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. 2019
  12. Published

    In Situ Crosslinking Bionanocomposite Hydrogels with Potential for Wound Healing Applications

    Leone, F., Firlak, M., Challen, K., Bonnefin, W., Onida, B., Wright, K. & Hardy, J., 14/11/2019, In: Journal of Functional Biomaterials. 10, 4, 15 p., 50.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Endocannabinoids and endocannabinoid-like compounds modulate hypoxia-induced permeability in CaCo-2 cells via CB1, TRPV1, and PPAR<alpha>

    Karwad, M. A., Couch, D. G., Wright, K., Tufarelli, C., Larvin, M., Lund, J. & O'Sullivan, S. E., 1/10/2019, In: Biochemical Pharmacology. 168, p. 465-472 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Single-cell Raman microscopy of microengineered cell scaffolds

    Baldock, S. J., Talari, A. C. S., Smith, R., Wright, K. L. & Ashton, L., 30/03/2019, In: Journal of Raman Spectroscopy. 50, 3, p. 371-379 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. 2017
  16. Published

    The role of CB1 in intestinal permeability and inflammation

    Karwad, M. A., Couch, D. G., Theophilidou, E., Sarmad, S., Barrett, D. A., Larvin, M., Wright, K. L., Lund, J. N. & O'Sullivan, S. E., 08/2017, In: FASEB Journal. 31, 8, p. 3267-3277 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Cannabidiol Reduces Leukemic Cell Size - But Is It Important?

    Kalenderoglou, N., Macpherson, T. & Wright, K. L., 24/03/2017, In: Frontiers in Pharmacology. 8, 9 p., 144.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα

    Karwad, M. A., Macpherson, T., Wang, B., Theophilidou, E., Sarmad, S., Barrett, D. A., Larvin, M., Wright, K. L., Lund, J. N. & O'Sullivan, S. E., 02/2017, In: FASEB Journal. 31, 2, p. 469-481 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. 2016
  20. Published

    Raman spectroscopy: an evolving technique for live cell studies

    Smith, R., Wright, K. L. & Ashton, L., 21/06/2016, In: Analyst. 2016, 12, p. 3590-3600 11 p.

    Research output: Contribution to Journal/MagazineLiterature reviewpeer-review

  21. Published

    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Wright, K. L., 21/01/2016, In: Autophagy. 12, 1, p. 1-222 222 p.

    Research output: Contribution to Journal/MagazineEditorialpeer-review

  22. 2014
  23. Published

    Cannabinoid-induced autophagy regulates suppressor of cytokine signaling (SOCS)-3 in intestinal epithelium

    Koay, L., Rigby, R. & Wright, K., 15/07/2014, In: American Journal of Physiology-Gastrointestinal and Liver Physiology. 307, p. G140-G148 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Physiological intestinal oxygen modulates the Caco-2 cell model and increases sensitivity to the phytocannabinoid cannabidiol

    MacPherson, T., Armstrong, J., Criddle, D. & Wright, K., 2014, In: In Vitro Cellular and Developmental Biology - Animal. 50, 5, p. 417-426 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. 2012
  26. Published

    Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability

    Alhamoruni, A., Wright, K., Larvin, M. & O'Sullivan, S. E., 04/2012, In: British Journal of Pharmacology. 165, 8, p. 2598-610 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. 2011
  28. Published

    Safety of medicine and the use of animals in research

    Archibald, K., Baxter, A. D., BéruBé, K., Bunton, D., Clotworthy, M., Coleman, B., Foster, C. S., Hillier, C., McFarlane, M., Patel, A., Pierscionek, B., Root, J., Thomas, G., Tsaioun, K., Wilkinson, J. M., Wilmut, I. & Wright, K. L., 29/10/2011, In: Lancet. 378, 9802, p. e2 1 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

  29. Published

    Open letter to UK Prime Minister David Cameron and Health Secretary Andrew Lansley on safety of medicines

    Archibald, K., Coleman, R., Foster, C. & Wright, K., 4/06/2011, In: Lancet. 377, 9781, p. 1915 1 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  30. 2010
  31. Published

    Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability.

    Alhamoruni, A., Lee, A. C., Wright, K. L., Larvin, M. & O'Sullivan, S. E., 10/2010, In: Journal of Pharmacology and Experimental Therapeutics. 335, 1, p. 92-102 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. 2008
  33. Published

    Long term cannabinoid receptor (CB1) blockade in obesity : implications for the development of colorectal cancer.

    Wright, K. L., Robertson, D. A. F., Moyer, M. P. & Ward, S. G., 15/04/2008, In: International Journal of Cancer. 122, 8, p. 1920-1921 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  34. Published

    Cannabinoid CB2 receptors in the gastrointestinal tract : a regulatory system in states of inflammation.

    Wright, K. L., Duncan, M. & Sharkey, K. A., 01/2008, In: British Journal of Pharmacology. 153, 2, p. 263-270 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  35. 2007
  36. Published

    Temporal variation in CB2R levels following T lymphocyte activation : evidence that cannabinoids modulate CXCL12-induced chemotaxis.

    Coopman, K., Smith, L. D., Wright, K. L. & Ward, S. G., 03/2007, In: International Immunopharmacology. 7, 3, p. 360-371 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  37. 2006
  38. Published

    Peripheral cannabinoid receptor, CB2, regulates bone mass.

    Ofek, O., Karsak, M., Leclerc, N., Fogel, M., Frenkel, B., Wright, K., Tam, J., Attar-Namdar, M., Kram, V., Shohami, E., Mechoulam, R., Zimmer, A. & Bab, I., 17/01/2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 3, p. 696-701 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  39. 2005
  40. Published

    The Chemokines CXCL9, CXCL10, and CXCL11 Differentially Stimulate Gαi-Independent Signaling and Actin Responses in Human Intestinal Myofibroblasts.

    Kouroumalis, A., Nibbs, R. J., Aptel, H., Wright, K. L., Kolios, G. & Ward, S. G., 15/10/2005, In: Journal of Immunology. 175, 8, p. 5403-5411 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  41. Published

    Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPARγ agonists: evidence for disparate functional effects which are independent of NF-κB and PPARγ

    Patel, K. M., Wright, K. L., Whittaker, P., Chakravarty, P., Watson, M. L. & Ward, S. G., 09/2005, In: Cellular Signalling. 17, 9, p. 1098-1110 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  42. Published

    Differential Expression of Cannabinoid Receptors in the Human Colon : Cannabinoids Promote Epithelial Wound Healing.

    Wright, K., Rooney, N., Feeney, M., Tate, J., Robertson, D., Welham, M. & Ward, S., 08/2005, In: Gastroenterology. 129, 2, p. 437-453 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  43. 2004
  44. Published

    Differential regulation of prostaglandin E biosynthesis by interferon-γ in colonic epithelial cells.

    Wright, K. L., Weaver, S. A., Patel, K., Coopman, K., Feeney, M., Kolios, G., Robertson, D. A. F. & Ward, S. G., 04/2004, In: British Journal of Pharmacology. 141, 7, p. 1091-1097 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  45. 2003
  46. Published

    Optimal Chemotactic Responses of Leukemic T Cells to Stromal Cell-Derived Factor-1 Requires the Activation of Both Class IA and IB Phosphoinositide 3-Kinases.

    Curnock, A. P., Sotsios, Y., Wright, K. L. & Ward, S. G., 15/04/2003, In: Journal of Immunology. 170, 8, p. 4021-4030 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  47. 2002
  48. Published

    Evidence That SHIP-1 Contributes to Phosphatidylinositol 3,4,5-Trisphosphate Metabolism in T Lymphocytes and Can Regulate Novel Phosphoinositide 3-Kinase Effectors.

    Freeburn, R. W., Wright, K. L., Burgess, S. J., Astoul, E., Cantrell, D. A. & Ward, S. G., 15/11/2002, In: Journal of Immunology. 169, 10, p. 5441-5450 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  49. 2001
  50. Published

    Regulatory role of phosphatidylinositol 3-kinase on TNF-α-induced cyclooxygenase 2 expression in colonic epithelial cells.

    Weaver, S. A., Russo, M. P., Wright, K. L., Kolios, G., Jobin, C., Robertson, D. A. F. & Ward, S. G., 04/2001, In: Gastroenterology. 120, 5, p. 1117-1127 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  51. 2000
  52. Published

    Interactions between Phosphatidylinositol 3-Kinase and Nitric Oxide: Explaining the Paradox

    Wright, K. L. & Ward, S. G., 09/2000, In: Molecular Cell Biology Research Communications. 4, 3, p. 137-143 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  53. Published

    Interleukin-13 inhibits nitric oxide production in human colonic mucosa.

    Kolios, G., Wright, K. L., Linehan, J. D., Robertson, D. A. F. & Westick, J., 2000, In: Hepato-Gastroenterology. 47, p. 714-717 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  54. 1999
  55. Published

    Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation : evidence for an IL-13-driven PI3-kinase-dependent survival mechanism.

    Wright, K., Kolios, G., Westwick, J. & Ward, S. G., 11/06/1999, In: Journal of Biological Chemistry. 274, 24, p. 17193-17201 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  56. Published

    C-X-C and C-C chemokine expression and secretion by the human colonic epithelial cell line, HT-29 : differential effect of T lymphocyte-derived cytokines.

    Kolios, G., Wright, K. L., Jordan, N. J., Leithead, J. B., Robertson, D. A. F. & Westwick, J., 02/1999, In: European Journal of Immunology. 29, 2, p. 530-536 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  57. 1997
  58. Published

    Activation of phosphatidylinositol 3-kinase by interleukin-13 - An inhibitory signal for inducible nitric-oxide synthase expression in the epithelial, cell line HT-29.

    Wright, K., Ward, S. G., Kolios, G. & Westwick, J., 9/05/1997, In: Journal of Biological Chemistry. 272, p. 12626-12633 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  59. Published

    Regulation of inflammatory mediator production in human colonic epithelial cells.

    Kolios, G., Wright, K. L., Jordan, N. J., Leithead, J. B., Murphy, C. T., Robertson, D. A. F. & Westwick, J., 1997, In: Hellenic Journal of Gastroenterology. 10, 2, p. 135-147 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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