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Dr Karen Wright

Lecturer

  1. 2019
  2. E-pub ahead of print

    Endocannabinoids and endocannabinoid-like compounds modulate hypoxia-induced permeability in CaCo-2 cells via CB1, TRPV1, and PPAR<alpha>

    Karwad, M. A., Couch, D. G., Wright, K., Tufarelli, C., Larvin, M., Lund, J. & O'Sullivan, S. E., 17/07/2019, In : Biochemical Pharmacology.

    Research output: Contribution to journalJournal article

  3. 2018
  4. E-pub ahead of print

    Single-cell Raman microscopy of microengineered cell scaffolds

    Baldock, S. J., Talari, A. C. S., Smith, R., Wright, K. L. & Ashton, L., 4/12/2018, In : Journal of Raman Spectroscopy.

    Research output: Contribution to journalJournal article

  5. 2017
  6. Published

    The role of CB1 in intestinal permeability and inflammation

    Karwad, M. A., Couch, D. G., Theophilidou, E., Sarmad, S., Barrett, D. A., Larvin, M., Wright, K. L., Lund, J. N. & O'Sullivan, S. E., 08/2017, In : FASEB Journal. 31, 8, p. 3267-3277 11 p.

    Research output: Contribution to journalJournal article

  7. Published

    Cannabidiol Reduces Leukemic Cell Size - But Is It Important?

    Kalenderoglou, N., Macpherson, T. & Wright, K. L., 24/03/2017, In : Frontiers in Pharmacology. 8, 9 p., 144.

    Research output: Contribution to journalJournal article

  8. Published

    Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα

    Karwad, M. A., Macpherson, T., Wang, B., Theophilidou, E., Sarmad, S., Barrett, D. A., Larvin, M., Wright, K. L., Lund, J. N. & O'Sullivan, S. E., 02/2017, In : FASEB Journal. 31, 2, p. 469-481 13 p.

    Research output: Contribution to journalJournal article

  9. 2016
  10. Published

    Raman spectroscopy: an evolving technique for live cell studies

    Smith, R., Wright, K. L. & Ashton, L., 21/06/2016, In : Analyst. 2016, 12, p. 3590-3600 11 p.

    Research output: Contribution to journalLiterature review

  11. Published

    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Wright, K. L., 21/01/2016, In : Autophagy. 12, 1, p. 1-222 222 p.

    Research output: Contribution to journalEditorial

  12. 2014
  13. Published

    Cannabinoid-induced autophagy regulates suppressor of cytokine signaling (SOCS)-3 in intestinal epithelium

    Koay, L., Rigby, R. & Wright, K., 15/07/2014, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 307, p. G140-G148 9 p.

    Research output: Contribution to journalJournal article

  14. Published

    Physiological intestinal oxygen modulates the Caco-2 cell model and increases sensitivity to the phytocannabinoid cannabidiol

    MacPherson, T., Armstrong, J., Criddle, D. & Wright, K., 2014, In : In Vitro Cellular and Developmental Biology - Animal. 50, 5, p. 417-426 10 p.

    Research output: Contribution to journalJournal article

  15. 2012
  16. Published

    Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability

    Alhamoruni, A., Wright, K., Larvin, M. & O'Sullivan, S. E., 04/2012, In : British Journal of Pharmacology. 165, 8, p. 2598-610 13 p.

    Research output: Contribution to journalJournal article

  17. 2011
  18. Published

    Safety of medicine and the use of animals in research

    Archibald, K., Baxter, A. D., BéruBé, K., Bunton, D., Clotworthy, M., Coleman, B., Foster, C. S., Hillier, C., McFarlane, M., Patel, A., Pierscionek, B., Root, J., Thomas, G., Tsaioun, K., Wilkinson, J. M., Wilmut, I. & Wright, K. L., 29/10/2011, In : Lancet. 378, 9802, p. e2 1 p.

    Research output: Contribution to journalLetter

  19. Published

    Open letter to UK Prime Minister David Cameron and Health Secretary Andrew Lansley on safety of medicines

    Archibald, K., Coleman, R., Foster, C. & Wright, K., 4/06/2011, In : Lancet. 377, 9781, p. 1915 1 p.

    Research output: Contribution to journalJournal article

  20. 2010
  21. Published

    Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability.

    Alhamoruni, A., Lee, A. C., Wright, K. L., Larvin, M. & O'Sullivan, S. E., 10/2010, In : Journal of Pharmacology and Experimental Therapeutics. 335, 1, p. 92-102 11 p.

    Research output: Contribution to journalJournal article

  22. 2008
  23. Published

    Long term cannabinoid receptor (CB1) blockade in obesity : implications for the development of colorectal cancer.

    Wright, K. L., Robertson, D. A. F., Moyer, M. P. & Ward, S. G., 15/04/2008, In : International Journal of Cancer. 122, 8, p. 1920-1921 2 p.

    Research output: Contribution to journalJournal article

  24. Published

    Cannabinoid CB2 receptors in the gastrointestinal tract : a regulatory system in states of inflammation.

    Wright, K. L., Duncan, M. & Sharkey, K. A., 01/2008, In : British Journal of Pharmacology. 153, 2, p. 263-270 8 p.

    Research output: Contribution to journalJournal article

  25. 2007
  26. Published

    Temporal variation in CB2R levels following T lymphocyte activation : evidence that cannabinoids modulate CXCL12-induced chemotaxis.

    Coopman, K., Smith, L. D., Wright, K. L. & Ward, S. G., 03/2007, In : International Immunopharmacology. 7, 3, p. 360-371 12 p.

    Research output: Contribution to journalJournal article

  27. 2006
  28. Published

    Peripheral cannabinoid receptor, CB2, regulates bone mass.

    Ofek, O., Karsak, M., Leclerc, N., Fogel, M., Frenkel, B., Wright, K., Tam, J., Attar-Namdar, M., Kram, V., Shohami, E., Mechoulam, R., Zimmer, A. & Bab, I., 17/01/2006, In : Proceedings of the National Academy of Sciences. 103, 3, p. 696-701 6 p.

    Research output: Contribution to journalJournal article

  29. 2005
  30. Published

    The Chemokines CXCL9, CXCL10, and CXCL11 Differentially Stimulate Gαi-Independent Signaling and Actin Responses in Human Intestinal Myofibroblasts.

    Kouroumalis, A., Nibbs, R. J., Aptel, H., Wright, K. L., Kolios, G. & Ward, S. G., 15/10/2005, In : Journal of Immunology. 175, 8, p. 5403-5411 9 p.

    Research output: Contribution to journalJournal article

  31. Published

    Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPARγ agonists: evidence for disparate functional effects which are independent of NF-κB and PPARγ

    Patel, K. M., Wright, K. L., Whittaker, P., Chakravarty, P., Watson, M. L. & Ward, S. G., 09/2005, In : Cellular Signalling. 17, 9, p. 1098-1110 13 p.

    Research output: Contribution to journalJournal article

  32. Published

    Differential Expression of Cannabinoid Receptors in the Human Colon : Cannabinoids Promote Epithelial Wound Healing.

    Wright, K., Rooney, N., Feeney, M., Tate, J., Robertson, D., Welham, M. & Ward, S., 08/2005, In : Gastroenterology. 129, 2, p. 437-453 17 p.

    Research output: Contribution to journalJournal article

  33. 2004
  34. Published

    Differential regulation of prostaglandin E biosynthesis by interferon-γ in colonic epithelial cells.

    Wright, K. L., Weaver, S. A., Patel, K., Coopman, K., Feeney, M., Kolios, G., Robertson, D. A. F. & Ward, S. G., 04/2004, In : British Journal of Pharmacology. 141, 7, p. 1091-1097 7 p.

    Research output: Contribution to journalJournal article

  35. 2003
  36. Published

    Optimal Chemotactic Responses of Leukemic T Cells to Stromal Cell-Derived Factor-1 Requires the Activation of Both Class IA and IB Phosphoinositide 3-Kinases.

    Curnock, A. P., Sotsios, Y., Wright, K. L. & Ward, S. G., 15/04/2003, In : Journal of Immunology. 170, 8, p. 4021-4030 10 p.

    Research output: Contribution to journalJournal article

  37. 2002
  38. Published

    Evidence That SHIP-1 Contributes to Phosphatidylinositol 3,4,5-Trisphosphate Metabolism in T Lymphocytes and Can Regulate Novel Phosphoinositide 3-Kinase Effectors.

    Freeburn, R. W., Wright, K. L., Burgess, S. J., Astoul, E., Cantrell, D. A. & Ward, S. G., 15/11/2002, In : Journal of Immunology. 169, 10, p. 5441-5450 10 p.

    Research output: Contribution to journalJournal article

  39. 2001
  40. Published

    Regulatory role of phosphatidylinositol 3-kinase on TNF-α-induced cyclooxygenase 2 expression in colonic epithelial cells.

    Weaver, S. A., Russo, M. P., Wright, K. L., Kolios, G., Jobin, C., Robertson, D. A. F. & Ward, S. G., 04/2001, In : Gastroenterology. 120, 5, p. 1117-1127 11 p.

    Research output: Contribution to journalJournal article

  41. 2000
  42. Published

    Interactions between Phosphatidylinositol 3-Kinase and Nitric Oxide: Explaining the Paradox

    Wright, K. L. & Ward, S. G., 09/2000, In : Molecular Cell Biology Research Communications. 4, 3, p. 137-143 7 p.

    Research output: Contribution to journalJournal article

  43. Published

    Interleukin-13 inhibits nitric oxide production in human colonic mucosa.

    Kolios, G., Wright, K. L., Linehan, J. D., Robertson, D. A. F. & Westick, J., 2000, In : Hepato-Gastroenterology. 47, p. 714-717 4 p.

    Research output: Contribution to journalJournal article

  44. 1999
  45. Published

    Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation : evidence for an IL-13-driven PI3-kinase-dependent survival mechanism.

    Wright, K., Kolios, G., Westwick, J. & Ward, S. G., 11/06/1999, In : Journal of Biological Chemistry. 274, 24, p. 17193-17201 9 p.

    Research output: Contribution to journalJournal article

  46. Published

    C-X-C and C-C chemokine expression and secretion by the human colonic epithelial cell line, HT-29 : differential effect of T lymphocyte-derived cytokines.

    Kolios, G., Wright, K. L., Jordan, N. J., Leithead, J. B., Robertson, D. A. F. & Westwick, J., 02/1999, In : European Journal of Immunology. 29, 2, p. 530-536 7 p.

    Research output: Contribution to journalJournal article

  47. 1997
  48. Published

    Activation of phosphatidylinositol 3-kinase by interleukin-13 - An inhibitory signal for inducible nitric-oxide synthase expression in the epithelial, cell line HT-29.

    Wright, K., Ward, S. G., Kolios, G. & Westwick, J., 9/05/1997, In : Journal of Biological Chemistry. 272, p. 12626-12633 8 p.

    Research output: Contribution to journalJournal article

  49. Published

    Regulation of inflammatory mediator production in human colonic epithelial cells.

    Kolios, G., Wright, K. L., Jordan, N. J., Leithead, J. B., Murphy, C. T., Robertson, D. A. F. & Westwick, J., 1997, In : Hellenic Journal of Gastroenterology. 10, 2, p. 135-147 13 p.

    Research output: Contribution to journalJournal article

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