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Dr Leonie Unterholzner

Senior Lecturer in Molecular Immunology

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  1. Published

    Viral evasion and subversion of pattern-recognition receptor signalling

    Bowie, A. G. & Unterholzner, L., 12/2008, In: Nature Immunology. 8, 12, p. 911-922 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

    Unterholzner, L., Sumner, R. P., Baran, M., Ren, H., Mansur, D. S., Bourke, N. M., Randow, F., Smith, G. L. & Bowie, A. G., 09/2011, In: PLoS Pathogens. 7, 9, e1002247.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities

    Unterholzner, L. & Bowie, A. G., 1/02/2008, In: Biochemical Pharmacology. 75, 3, p. 589-602 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    The interferon response to intracellular DNA: why so many receptors?

    Unterholzner, L., 11/2013, In: Immunobiology. 218, 11, p. 1312-1321 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor

    Jin, T., Perry, A., Jiang, J., Smith, P., Curry, J. A., Unterholzner, L., Jiang, Z., Horvath, G., Rathinam, V. A., Johnstone, R. W., Hornung, V., Latz, E., Bowie, A. G., Fitzgerald, K. A. & Xiao, T. S., 20/04/2012, In: Immunity. 36, 4, p. 561-571 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Structural mechanism of DNA recognition by the p204 HIN domain

    Fan, X., Jiang, J., Zhao, D., Chen, F., Ma, H., Smith, P., Unterholzner, L., Xiao, T. S. & Jin, T., 18/03/2021, In: Nucleic Acids Research. 49, 5, p. 2959-2972 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Structural and Evolutionary Insights Into the Binding of Host Receptors by the Rabies Virus Glycoprotein

    Khalifa, M. E., Unterholzner, L. & Munir, M., 11/10/2021, In: Frontiers in cellular and infection microbiology. 11, 13 p., 736114.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway

    Fukuhara, N., Ebert, J., Unterholzner, L., Lindner, D., Izaurralde, E. & Conti, E., 18/02/2005, In: Molecular Cell. 17, 4, p. 537-547 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    SMG7 acts as a molecular link between mRNA surveillance and mRNA decay

    Unterholzner, L. & Izaurralde, E., 19/11/2004, In: Molecular Cell. 16, 4, p. 587-596 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

    Horan, K. A., Hansen, K., Jakobsen, M. R., Holm, C. K., Søby, S., Unterholzner, L., Thompson, M., West, J. A., Iversen, M. B., Rasmussen, S. B., Ellermann-Eriksen, S., Kurt-Jones, E., Landolfo, S., Damania, B., Melchjorsen, J., Bowie, A. G., Fitzgerald, K. A. & Paludan, S. R., 1/03/2013, In: Journal of Immunology. 190, 5, p. 2311-2319 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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