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Dr Nikki Copeland

Senior Lecturer in Biomedicine/Director of Studies Biomedical Science

  1. 2023
  2. Published

    Light-responsive biomaterials for ocular drug delivery

    Abdelmohsen, H., Copeland, N. & Hardy, J., 31/08/2023, In: Drug Delivery and Translational Research. 13, 8, p. 2159-2182 24 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. 2022
  4. Published

    Light-responsive systems for ocular drug delivery

    Abdelmohsen, H., Copeland, N. & Hardy, J., 5/09/2022.

    Research output: Contribution to conference - Without ISBN/ISSN Posterpeer-review

  5. Published

    Dbf4-Cdc7 (DDK) Inhibitor PHA-767491 Displays Potent Anti-Proliferative Effects via Crosstalk with the CDK2-RB-E2F Pathway

    Pauzaite, T., Tollitt, J., Sopaci, B., Caprani, L., Iwanowytsch, O., Thacker, U., Hardy, J. G., Allinson, S. L. & Copeland, N. A., 19/08/2022, In: Biomedicines. 10, 8, 20 p., e2012.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. 2021
  7. Published

    Detection of CRISPR-Cas9-Mediated Mutations Using a Carbon Nanotube-Modified Electrochemical Genosensor

    Kivrak, E., Pauzaite, T., Copeland, N., Hardy, J., Kara, P., Firlak, M., Yardimci, A., Yilmaz, S., Palaz, F. & Ozsoz, M., 8/01/2021, In: Biosensors. 11, 1, 12 p., 17.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. 2020
  9. Published

    Re-evaluation of Diadenosine Tetraphosphate (Ap4A) From a Stress Metabolite to Bona Fide Secondary Messenger

    Ferguson, F., Sandy McLennan, P., Urbaniak, M., Nigel Jones, D. & Copeland, N., 17/11/2020, In: Frontiers in Molecular Biosciences. 7, 18 p., 606807.

    Research output: Contribution to Journal/MagazineBook/Film/Article reviewpeer-review

  10. Published

    Identification of DHX9 as a cell cycle regulated nucleolar recruitment factor for CIZ1

    Thacker, U., Pauzaite, T., Tollitt, J., Twardowska, M., Harrison, C., Dowle, A., Coverley, D. & Copeland, N. A., 22/10/2020, In: Scientific Reports. 10, 1, 13 p., 18103.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. 2017
  12. Published

    Emerging Roles for Ciz1 in Cell Cycle Regulation and as a Driver of Tumorigenesis

    Pauzaite, T., Thacker, U., Tollitt, J. & Copeland, N. A., 2017, In: Biomolecules. 7, 1

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. 2016
  14. Published

    NUDT2 disruption elevates diadenosine tetraphosphate (Ap4A) and down-regulates immune response and cancer promotion genes

    Marriott, A. S., Vasieva, O., Fang, Y., Copeland, N. A., McLennan, A. G. & Jones, N. J., 4/05/2016, In: PLoS ONE. 11, 5, 35 p., e0154674.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. 2015
  16. Published

    Diadenosine 5′, 5′′′-P1,P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication.

    Marriott, A. S., Copeland, N., Cunningham, R., Wilkinson, M. C., McLennan, A. G. & Jones, N. J., 09/2015, In: DNA Repair. 33, p. 90-100 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Cyclin A/CDK2 mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication

    Copeland, N., Sercombe, H. E., Wilson, R. H. C. & Coverley, D., 15/04/2015, In: Journal of Cell Science. 128, 8, p. 1518-1527 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria

    Rassam, P., Copeland, N., Birkholz, O., Toth, C., Chavent, M., Cross, S., Housden, N., Kaminska, R., Seger, U., Quinn, D., Garrod, T., Sansom, M. S., Piehler, J., Baumann, C. G. & Kleanthous, C., 2015, In: Nature. 523, p. 333–336 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. 2013
  20. Published

    Lit Protease

    Copeland, N. A. & Kleanthous, C., 29/08/2013, Handbook of Proteolytic Enzymes. Elsevier Ltd, Vol. 3. p. 3761-3764 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  21. 2012
  22. Published

    Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cells

    Greaves, E. A., Copeland, N. A., Coverley, D. & Ainscough, J. F. X., 15/05/2012, In: Journal of Cell Science. 125, p. 2466-2477 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. 2011
  24. Published

    Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells

    Munkley, J., Copeland, N. A., Moignard, V., Knight, J. R. P., Greaves, E., Ramsbottom, S. A., Pownall, M. E., Southgate, J., Ainscough, J. F-X. & Coverley, D., 2011, In: Nucleic Acids Research. 39, 7, p. 2671-2677 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. 2010
  26. Published

    Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro

    Copeland, N. A., Sercombe, H. E., Ainscough, J. F. X. & Coverley, D., 1/04/2010, In: Journal of Cell Science. 123, 7, p. 1108-1115 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. 2007
  28. Published

    Cancer-associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1.

    Rahman, F. A., Ainscough, J. F. X., Copeland, N. & Coverley, D., 10/2007, In: Human Mutation. 28, 10, p. 993-1004 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  29. 2005
  30. Published

    The role of an activating peptide in protease-mediated suicide of Escherichia coli K12.

    Copeland, N. & Kleanthous, C., 7/01/2005, In: Journal of Biological Chemistry. 280, 1, p. 112-117 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. 2004
  32. Published

    Identification of essential residues within Lit, a cell death peptidase of Escherichia coli K-12.

    Copeland, N., Bingham, R., Georgiou, T., Cooper, P. & Kleanthous, C., 22/06/2004, In: Biochemistry. 43, 24, p. 7948-7953 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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