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Professor Paul McKean

Head of Department, Senior Lecturer

  1. Published

    Tubulin-binding cofactor C domain-containing protein TBCCD1 orchestrates cytoskeletal filament formation

    Andre, J., Harrison, S., Towers, K., Qi, X., Vaughan, S., McKean, P. & Ginger, M., 12/2013, In: Journal of Cell Science. 126, p. 5350-5356 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    An alternative model for the role of RP2 in flagellum assembly in the African trypanosome: RP2 function in T. brucei

    Andre, J., Kerry, L., Qi, X., Hawkins, E., Drižytė, K., Ginger, M. & McKean, P., 3/01/2014, In: Journal of Biological Chemistry. 289, 1, p. 464 –475 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Cell cycle synchronisation of Trypanosoma brucei by centrifugal counter-flow elutriation reveals the timing of nuclear and kinetoplast DNA replication

    Benz, C., Dondelinger, F., McKean, P. G. & Urbaniak, M. D., 14/12/2017, In: Scientific Reports. 7, 10 p., 17599.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    The flagella connector of Trypanosoma brucei : an unusual mobile transmembrane junction.

    Briggs, L., McKean, P. G., Baines, A., Moreira-Leite, F., Davidge, J., Vaughan, S. & Gull, K., 04/2004, In: Journal of Cell Science. 117, 9, p. 1641-1651 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Flagellar motility is required for the viability of the bloodstream trypanosome.

    Broadhead, R., Dawe, H. R., Farr, H., Griffiths, S., Hart, S. R., Portman, N., Shaw, M. K., Ginger, M. L., Gaskell, S. J., McKean, P. G. & Gull, K., 9/03/2006, In: Nature. 440, 7081, p. 224-227 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Redistribution of FLAgellar Member 8 during the trypanosome life cycle: Consequences for cell fate prediction

    Calvo-Álvarez, E., Bonnefoy, S., Salles, A., Benson, F. E., McKean, P. G., Bastin, P. & Rotureau, B., 30/09/2021, In: Cellular Microbiology. 23, 9, e13347.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagella membrane formation.

    Davidge, J. A., Shawcross, E., Dickinson, H. A., Towers, K., Ginger, M. L., McKean, P. G. & Gull, K., 2006, In: Journal of Cell Science. 119, 19, p. 3935-3943 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axonemes of trypanosomes.

    Gadelha, C., Wickstead, B., McKean, P. G. & Gull, K., 15/06/2006, In: Journal of Cell Science. 119, 12, p. 2405-2413 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Swimming with protists : perception, motility and flagellum assembly.

    Ginger, M. L., Portman, N. & McKean, P. G., 11/2008, In: Nature Reviews in Microbiology. 6, 11, p. 838-850 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Proteomic insights into parasite biology

    Ginger, M. L., McKean, P. G., Burchmore, R. & Grant, K. M., 08/2012, In: Parasitology. 139, 9, p. 1101-1102 2 p.

    Research output: Contribution to Journal/MagazineJournal article

  11. Published

    Flagellum function and assembly during the Leishmania life cycle.

    Gluenz, E., Ginger, M. L. & McKean, P. G., 08/2010, In: Current Opinion in Microbiology. 13, 4, p. 473-479 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Cell structure, cell division and cell cycle.

    Hammarton, T., Wickstead, B. & McKean, P. G., 2007, Trypanosomes : after the genome. Barry, D., McCulloch, R., Mottram, J. & Acosta-Serrano, A. (eds.). Wymondham: Horizon Bioscience, p. 239-280 42 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  13. Published

    Variation in Basal Body Localisation and Targeting of Trypanosome RP2 and FOR20 Proteins

    Harmer, J., Qi, X., Toniolo, G., Patel, A., Shaw, H., Benson, F. E., Ginger, M. L. & McKean, P. G., 08/2017, In: Protist. 168, 4, p. 452-466 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    A centriolar FGR1 oncogene partner-like protein required for paraflagellar rod assembly, but not axoneme assembly in African trypanosomes

    Harmer, J., Towers, K., Addison, M., Vaughan, S., Ginger, M. L. & McKean, P. G., 07/2018, In: Open biology. 8, 7, 13 p., 170218.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Analysis of the trypanosome flagellar proteome using a combined electron transfer collisionally activated dissociation strategy.

    Hart, S. R., Wai Lau, K. W., Hao, Z., Broadhead, R., Portman, N., Huhmer, A., Gull, K., McKean, P. G., Hubbard, S. J. & Gaskell, S. J., 02/2009, In: Journal of The American Society for Mass Spectrometry. 20, 2, p. 167-175 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Characterisation of a differentially expressed protein that shows an unusual localisation to intracellular membranes in Leishmania major.

    Kneupfer, E., Stierhof, Y. D., McKean, P. G. & Smith, D. F., 1/06/2001, In: Biochemical Journal. 356, 2, p. 335-344 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Diversity in repeat-containing surface proteins of Leishmania major.

    McKean, P. G., Trenholme, K. R., Rangarajan, D., Keen, J. K. & Smith, D. F., 06/1997, In: Molecular and Biochemical Parasitology. 86, 2, p. 225-235 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Characterisation of a second protein encoded by the differentially regulated LmcDNA16 gene family of Leishmania major.

    McKean, P. G., Delahay, R., Pimenta, P. F. & Smith, D. F., 04/1997, In: Molecular and Biochemical Parasitology. 85, 2, p. 221-231 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    A single amino acid determines the specificity of a monoclonal antibody which inhibits Plasmodium chabaudi AS in vivo.

    McKean, P. G., O'Dea, K. P. & Brown, K. N., 12/1993, In: Molecular and Biochemical Parasitology. 62, 2, p. 211-221 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Nucleotide sequence analysis and epitope mapping of the merozoite surface protein 1 from Plasmodium chabaudi chabaudi AS.

    McKean, P. G., O’Dea, K. P. & Brown, K. N., 12/1993, In: Molecular and Biochemical Parasitology. 62, 2, p. 199-209 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    The action of a mast cell protease on the cuticular collagens of Necator americanus.

    McKean, P. G. & Pritchard, D. I., 05/1989, In: Parasite Immunology. 11, 3, p. 293-297 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Identification and characterisation of a RAD51 gene from Leishmania major.

    McKean, P. G., Keen, J. G., Smith, D. F. & Benson, F. E., 07/2001, In: Molecular and Biochemical Parasitology. 115, 2, p. 209-216 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Coordination of cell cycle progression and cytokinesis in Trypanosoma brucei.

    McKean, P. G., 12/2003, In: Current Opinion in Microbiology. 6, 6, p. 600-607 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    γ-Tubulin Functions in the Nucleation of a Discrete Subset of Microtubules in the Eukaryotic Flagellum.

    McKean, P. G., Baines, A., Vaughan, S. & Gull, K., 1/04/2003, In: Current Biology. 13, 7, p. 598-602 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    The extended tubulin superfamily.

    McKean, P. G., Vaughan, S. & Gull, K., 08/2001, In: Journal of Cell Science. 114, 15, p. 2723-2733 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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