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Dr Rachael Rigby

Senior Lecturer

  1. 2020
  2. Published

    Hypothesis: Bacterial induced inflammation disrupts the orderly progression of the stem cell hierarchy and has a role in the pathogenesis of breast cancer

    Marwaha, A. K., Morris, J. A. & Rigby, R. J., 31/03/2020, In : Medical Hypotheses. 136, 5 p., 109530.

    Research output: Contribution to journalJournal article

  3. 2017
  4. Published

    Loop ileostomy-mediated fecal stream diversion is associated with microbial dysbiosis

    Beamish, E., Johnson, J., Shaw, E., Scott, N. A., Bhowmick, A. & Rigby, R. J., 3/09/2017, In : Gut Microbes. 8, 5, p. 467-478 12 p.

    Research output: Contribution to journalJournal article

  5. Published

    Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation.

    Shaw, E. J., Smith, E., Whittingham-Dowd, J. K., Hodges, M. D. J., Else, K. J. & Rigby, R. J., 09/2017, In : Immunity, Inflammation and Disease. 5, 3, p. 336-345 10 p.

    Research output: Contribution to journalJournal article

  6. 2016
  7. Published

    Intestinal bacteria are necessary for doxorubicin-induced intestinal damage but not for doxorubicin-induced apoptosis

    Rigby, R. J., Carr, J., Orgel, K., King, S. L., Lund, P. K. & Dekaney, C. M., 09/2016, In : Gut Microbes. 7, 5, p. 414-423 10 p.

    Research output: Contribution to journalJournal article

  8. 2015
  9. Published

    Intestinal epithelial Suppressor of Cytokine Signaling (SOCS) 3 enhances microbial induced inflammatory TNFα, contributing to epithelial barrier dysfunction

    Thagia, I., Shaw, E. J., Smith, E., Else, K. J. & Rigby, R. J., 1/01/2015, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 308, 1, p. G25-G31 7 p.

    Research output: Contribution to journalJournal article

  10. 2014
  11. Published

    Human gut dendritic cells drive aberrant gut-specific T-cell responses in ulcerative colitis, characterized by increased IL-4 production and loss of IL-22 and IFNγ

    Mann, E. R., Bernardo, D., Ng, S. C., Rigby, R. J., Al-hassi, H. O., Landy, J., Peake, S. T. C., Spranger, H., English, N. R., Thomas, L. V., Stagg, A. J., Knight, S. C. & Hart, A. L., 1/12/2014, In : Inflammatory Bowel Diseases. 20, 12, p. 2299-2307 9 p.

    Research output: Contribution to journalJournal article

  12. Published

    Cannabinoid-induced autophagy regulates suppressor of cytokine signaling (SOCS)-3 in intestinal epithelium

    Koay, L., Rigby, R. & Wright, K., 15/07/2014, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 307, p. G140-G148 9 p.

    Research output: Contribution to journalJournal article

  13. Published
  14. Published

    Suppressor of cytokine signalling three regulated intestinal epithelial cell turnover: impact on microbial resistance

    Shaw, E., Else, K. & Rigby, R., 2014.

    Research output: Contribution to conference - Without ISBN/ISSN Poster

  15. 2011
  16. Published

    Inflammation Enhances Resection-Induced Intestinal Adaptive Growth in IL-10 Null Mice

    Speck, K. E., Garrison, A. P., Rigby, R. J., von Allmen, D. C., Lund, P. K. & Helmrath, M. A., 1/06/2011, In : Journal of Surgical Research. 168, 1, p. 62-69 8 p.

    Research output: Contribution to journalJournal article

  17. 2010
  18. Published

    The role of suppressor of cytokine signalling 3 in regulating TLR-mediated intestinal epithelial cell homeostasis and repair

    Thagia, I. & Rigby, R., 12/2010, In : Clinical and Experimental Immunology. 131, p. 124-125 2 p.

    Research output: Contribution to journalSpecial issue

  19. Published

    High-Fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse

    Ding, S., Chi, M. M., Scull, B. P., Rigby, R., Schwerbrock, N. M. J., Magness, S., Jobin, C. & Lund, P. K., 16/08/2010, In : PLoS ONE. 5, 8, p. - 13 p., e12191.

    Research output: Contribution to journalJournal article

  20. 2009
  21. Published

    A new animal model of postsurgical bowel inflammation and fibrosis: the effect of commensal microflora

    Rigby, R. J., Hunt, M. R., Scull, B. P., Simmons, J. G., Speck, K. E., Helmrath, M. A. & Lund, P. K., 08/2009, In : Gut. 58, 8, p. 1104-1112 9 p.

    Research output: Contribution to journalJournal article

  22. Published

    Intestinal Epithelial Cell (IEC)-Specific Deletion of Suppressor of Cytokine Signaling 3 (SOCS3) in Interleukin-10 Null Mice Promotes Duodenal Tumors Independent of Inflammation: Detection with a Cathepsin-B Activatable Molecular Probe

    Scull, B., Rigby, R. J., Newton, V. A., Hamilton, K., Morgan, D. & Lund, P. K., 05/2009, In : Gastroenterology. 136, 5 Supplement 1, p. A114-A114 1 p., 718.

    Research output: Contribution to journalSpecial issue

  23. 2008
  24. Published

    What Are the Mechanisms of Fibrosis in IBD?

    Lund, P. K. & Rigby, R. J., 10/2008, In : Inflammatory Bowel Diseases. 14, Supplement 2, p. S127-S128 2 p.

    Research output: Contribution to journalLetter

  25. Published

    Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection

    Dekaney, C. M., von Allmen, D. C., Garrison, A. P., Rigby, R. J., Lund, P. K., Henning, S. J. & Helmrath, M. A., 08/2008, In : Surgery. 144, 2, p. 174-181 8 p.

    Research output: Contribution to journalJournal article

  26. 2007
  27. Published

    Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice

    Dekaney, C. M., Fong, J. J., Rigby, R. J., Lund, P. K., Henning, S. J. & Helmrath, M. A., 11/2007, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 293, 5, p. G1013-G1022 10 p.

    Research output: Contribution to journalJournal article

  28. Published

    Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon

    Rigby, R. J., Simmons, J. G., Greenhalgh, C. J., Alexander, W. S. & Lund, P. K., 19/07/2007, In : Oncogene. 26, 33, p. 4833-4841 9 p.

    Research output: Contribution to journalJournal article

  29. 2006
  30. Published

    SOC-ing it to tumors: suppressors of cytokine signaling as tumor repressors

    Lund, P. K. & Rigby, R. J., 07/2006, In : Gastroenterology. 131, 1, p. 317-319 3 p.

    Research output: Contribution to journalEditorial

  31. 2005
  32. Published

    Characteristics of intestinal dendritic cells in inflammatory bowel diseases

    Hart, A. L., Al-Hassi, H. O., Rigby, R. J., Bell, S. J., Emmanuel, A. V., Knight, S. C., Kamm, M. A. & Stagg, A. J., 07/2005, In : Gastroenterology. 129, 1, p. 50-65 16 p.

    Research output: Contribution to journalJournal article

  33. Published

    Production of interleukin (IL)-10 and IL-12 by murine colonic dendritic cells in response to microbial stimuli

    Rigby, R. J., Knight, S. C., Kamm, M. A. & Stagg, A. J., 02/2005, In : Clinical and Experimental Immunology. 139, 2, p. 245-256 12 p.

    Research output: Contribution to journalJournal article

  34. 2001
  35. Published

    Migration and maturation of human colonic dendritic cells

    Bell, S. J., Rigby, R., English, N., Mann, S. D., Knight, S. C., Kamm, M. A. & Stagg, A. J., 15/04/2001, In : Journal of Immunology. 166, 8, p. 4958-4967 10 p.

    Research output: Contribution to journalJournal article

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