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Research

Dr Rachael Rigby

Formerly at Lancaster University

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  1. 2023
  2. Published

    Delay in loop ileostomy reversal surgery does not impact upon post-operative clinical outcomes. Complications are associated with an increased loss of microflora in the defunctioned intestine

    Beamish, E. L., Johnson, J., Shih, B., Killick, R., Dondelinger, F., McGoran, C., Brewster-Craig, C., Davies, A., Bhowmick, A. & Rigby, R. J., 31/12/2023, In: Gut Microbes. 15, 1, 2199659.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2022
  4. Published

    SARS-CoV-2 Interacts with Mucosal Dysbiosis to Cause the Wide Range of Disease Seen in Covid-19

    Morris, J., Shepherd, R., Wray, M., Diep, P-T. & Rigby, R., 26/03/2022, In: Austin Journal of Pulmonary and Respiratory Medicine. 9, 1, 7 p., 1086.

    Research output: Contribution to Journal/Magazine › Review article › peer-review

  5. 2021
  6. Published

    A hierarchical Bayesian approach for detecting global microbiome associations

    Hatami, F., Beamish, E., Davies, A., Rigby, R. & Dondelinger, F., 1/11/2021, In: Statistical Applications in Genetics and Molecular Biology. 20, 3, p. 85-100 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. 2020
  8. Published

    Hypothesis: Bacterial induced inflammation disrupts the orderly progression of the stem cell hierarchy and has a role in the pathogenesis of breast cancer

    Marwaha, A. K., Morris, J. A. & Rigby, R. J., 31/03/2020, In: Medical Hypotheses. 136, 5 p., 109530.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2017
  10. Published

    Loop ileostomy-mediated fecal stream diversion is associated with microbial dysbiosis

    Beamish, E., Johnson, J., Shaw, E., Scott, N. A., Bhowmick, A. & Rigby, R. J., 3/09/2017, In: Gut Microbes. 8, 5, p. 467-478 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation.

    Shaw, E. J., Smith, E., Whittingham-Dowd, J. K., Hodges, M. D. J., Else, K. J. & Rigby, R. J., 09/2017, In: Immunity, Inflammation and Disease. 5, 3, p. 336-345 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. 2016
  13. Published

    Intestinal bacteria are necessary for doxorubicin-induced intestinal damage but not for doxorubicin-induced apoptosis

    Rigby, R. J., Carr, J., Orgel, K., King, S. L., Lund, P. K. & Dekaney, C. M., 09/2016, In: Gut Microbes. 7, 5, p. 414-423 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. 2015
  15. Published

    Intestinal epithelial Suppressor of Cytokine Signaling (SOCS) 3 enhances microbial induced inflammatory TNFα, contributing to epithelial barrier dysfunction

    Thagia, I., Shaw, E. J., Smith, E., Else, K. J. & Rigby, R. J., 1/01/2015, In: American Journal of Physiology-Gastrointestinal and Liver Physiology. 308, 1, p. G25-G31 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. 2014
  17. Published

    Human gut dendritic cells drive aberrant gut-specific T-cell responses in ulcerative colitis, characterized by increased IL-4 production and loss of IL-22 and IFNγ

    Mann, E. R., Bernardo, D., Ng, S. C., Rigby, R. J., Al-hassi, H. O., Landy, J., Peake, S. T. C., Spranger, H., English, N. R., Thomas, L. V., Stagg, A. J., Knight, S. C. & Hart, A. L., 1/12/2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2299-2307 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Cannabinoid-induced autophagy regulates suppressor of cytokine signaling (SOCS)-3 in intestinal epithelium

    Koay, L., Rigby, R. & Wright, K., 15/07/2014, In: American Journal of Physiology-Gastrointestinal and Liver Physiology. 307, p. G140-G148 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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