Estimation of AUC from 0 to Infinity in Serial Sacrifice Designs.

Wolfsegger, M. J. & Jaki, T., 12/2005, In: Journal of Pharmacokinetics and Pharmacodynamics. 32, 5-6, p. 757-766 10 p.

Research output: Contribution to journal › Journal article › peer-review

Simultaneous confidence intervals by iteratively adjusted alpha for relative effects in the one-way layout.

Wolfsegger, M. J. & Jaki, T., 2006, In: Statistics and Computing. 16, 1, p. 15-23 9 p.

Research output: Contribution to journal › Journal article › peer-review

Book review: Applied Nonparametric Statistical Methods.

Jaki, T., 2008, In: Journal of Biopharmaceutical Statistics. 18, 2, p. 393-395 3 p.

Research output: Contribution to journal › Journal article › peer-review

Maximum kernel likelihood estimation

Jaki, T. & West, R. W., 2008, In: Journal of Computational and Graphical Statistics. 17, 4, p. 976-993 18 p.

Research output: Contribution to journal › Journal article › peer-review

Using Multilevel Mixtures to Evaluate Intervention Effects in Group Randomized Trials.

Van Horn, M. L., Fagan, A. A., Jaki, T., Brown, E. C., Hawkins, J. D., Arthur, M. W., Abbott, R. D. & Catalano, R. F., 04/2008, In: Multivariate Behavioral Research. 43, 2, p. 289-326 38 p.

Research output: Contribution to journal › Journal article › peer-review

Confidence Intervals for Ratios of AUC's in the Case of Serial Sampling : A Comparison of Seven Methods.

Jaki, T., Wolfsegger, M. J. & Ploner, M., 01/2009, In: Pharmaceutical Statistics. 8, 1, p. 12-24 13 p.

Research output: Contribution to journal › Journal article › peer-review

One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

Whitehead, J. & Jaki, T., 28/02/2009, In: Statistics in Medicine. 28, 5, p. 828-847 20 p.

Research output: Contribution to journal › Journal article › peer-review

A theoretical framework for estimation of AUCs in complete and incomplete sampling designs.

Jaki, T. & Wolfsegger, M. J., 05/2009, In: Statistics in Biopharmaceutical Research. 1, 2, p. 176-184 9 p.

Research output: Contribution to journal › Journal article › peer-review

Using a problem-based approach to teach statistics to postgraduate science students : a case study.

Jaki, T. & Autin, M., 05/2009, In: MSOR Connections. 9, 2, p. 40-47 8 p.

Research output: Contribution to journal › Journal article › peer-review

Assessing differential effects: Applying regression mixture models to identify variations in the influence of family resources on academic achievement.

Van Horn, M. L., Jaki, T., Maysn, K., Ramey, S. L., Smith, J. A. & Antaramian, S., 09/2009, In: Developmental Psychology. 45, 5, p. 1298-1313 16 p.

Research output: Contribution to journal › Journal article › peer-review

A note on statistical analysis of organ weights in non-clinical toxicological studies.

Wolfsegger, M. J., Jaki, T., Dietrich, B., Kunzler, J. A. & Barker, K., 10/2009, In: Toxicology and Applied Pharmacology. 240, 1, p. 117-122 6 p.

Research output: Contribution to journal › Journal article › peer-review

Non-compartmental estimation of pharmacokinetic parameters in serial sampling designs.

Wolfsegger, M. J. & Jaki, T., 10/2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 36, 5, p. 479-494

Research output: Contribution to journal › Journal article › peer-review

Recording lectures as a service in a service course.

Jaki, T., 11/2009, In: Journal of Statistics Education. 17, 3

Research output: Contribution to journal › Journal article › peer-review

Assessing systemic drug exposure in repeated dose toxicity studies in the case of complete and incomplete sampling.

Wolfsegger, M. J. & Jaki, T., 12/2009, In: Biometrical Journal. 51, 6, p. 1017-1026 10 p.

Research output: Contribution to journal › Journal article › peer-review

Book review : Bioequivalence and statistics in clinical pharmacology.

Jaki, T., 04/2010, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 173, 2, p. 467-468 2 p.

Research output: Contribution to journal › Book/Film/Article review

Establishing bioequivalence in complete and incomplete data designs using AUCs.

Jaki, T., Wolfsegger, M. J. & Lawo, J-P., 07/2010, In: Journal of Biopharmaceutical Statistics. 20, 4, p. 803-820 18 p.

Research output: Contribution to journal › Journal article › peer-review

Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for hemophilia A.

Baumgartner, B., Jaki, T., Wolfsegger, M. J., Eder, B., Schiviz, A., Schwarz, H. P. & Muchitsch, E. M., 07/2010, In: Laboratory Animals. 44, 3, p. 211-217 7 p.

Research output: Contribution to journal › Journal article › peer-review

Probabilistic relabelling strategies for the label switching problem in Bayesian mixture models.

Sperrin, M., Jaki, T. & Wit, E., 07/2010, In: Statistics and Computing. 20, 3, p. 357-366 10 p.

Research output: Contribution to journal › Journal article › peer-review

Direct effects testing : a two-stage procedure to test for effect size and variable importance for correlated binary predictors and a binary response.

Sperrin, M. & Jaki, T., 30/10/2010, In: Statistics in Medicine. 29, 24, p. 2544-2556 13 p.

Research output: Contribution to journal › Journal article

Symmetric maximum kernel likelihood estimation.

Jaki, T. & West, R. W., 02/2011, In: Journal of Statistical Computation and Simulation. 81, 2, p. 193-206 14 p.

Research output: Contribution to journal › Journal article › peer-review

Estimation of pharmacokinetic parameters with the R package PK.

Jaki, T. & Wolfsegger, M. J., 05/2011, In: Pharmaceutical Statistics. 10, 2, p. 284-288 5 p.

Research output: Contribution to journal › Journal article › peer-review

A formal comparison of different methods for establishing cut points to distinguish positive and negative samples in immunoassays.

Jaki, T., Lawo, J-P., Wolfsegger, M. J., Singer, J., Allacher, P. & Horling, F., 15/07/2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 5, p. 1148-1156 9 p.

Research output: Contribution to journal › Journal article › peer-review

Non-compartmental estimation of pharmacokinetic parameters for flexible sampling designs

Jaki, T. & Wolfsegger, M. J., 2012, In: Statistics in Medicine. 31, 11-12, p. 1059-1073 25 p.

Research output: Contribution to journal › Journal article › peer-review

Not quite normal: Consequences of violating the assumption of normality with regression mixture models

Van Horn, M. L., Smith, J., Fagan, A., Jaki, T., Maysn, K., Hawkins, D., Feaster, D. & Howe, G., 2012, In: Structural Equation Modeling. 19, 2, p. 227-249 23 p.

Research output: Contribution to journal › Journal article › peer-review

A generalized Dunnett Test for Multi-arm Multi-stage Clinical Studies with Treatment Selection

Magirr, D., Jaki, T. & Whitehead, J., 06/2012, In: Biometrika. 99, 2, p. 494-501 8 p.

Research output: Contribution to journal › Journal article › peer-review

Recovering Independent Associations in Genetics: A Comparison

Sperrin, M. & Jaki, T., 08/2012, In: Journal of Computational Biology. 19, 8, p. 978–987 10 p.

Research output: Contribution to journal › Journal article › peer-review

A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

Whitehead, J., Thygesen, H., Jaki, T., Davis, S., Halford, S., Turner, H., Cook, N. & Jodrell, D., 15/08/2012, In: Statistics in Medicine. 31, 18, p. 1931-1943 13 p.

Research output: Contribution to journal › Journal article › peer-review

Optimal design of multi-arm multi-stage trials

Wason, J. & Jaki, T., 30/12/2012, In: Statistics in Medicine. 31, 30, p. 4269-4279 11 p.

Research output: Contribution to journal › Journal article › peer-review

Finite mixtures for simultaneously modelling differential effects and non-normal distributions

George, M., Yang, N., Jaki, T., Feaster, D., Lamont, A. E., Van Horn, M. L. & Wilson, D. K., 2013, In: Multivariate Behavioral Research. 48, 6, p. 816-844 29 p.

Research output: Contribution to journal › Journal article › peer-review

Simultaneous confidence intervals that are compatible with closed testing in adaptive designs

Magirr, D., Jaki, T., Posch, M. & Klingelmueller, F., 2013, In: Biometrika. 100, 4, p. 985-996 12 p.

Research output: Contribution to journal › Journal article › peer-review

Using regression mixture models with non-normal data: examining an ordered polytomous approach

George, M., Yang, N., Van Horn, M. L., Smith, J., Jaki, T., Feaster, D., Maysn, K. & Howe, G., 2013, In: Journal of Statistical Computation and Simulation. 83, 4, p. 757-770 14 p.

Research output: Contribution to journal › Journal article › peer-review

Considerations on covariates and endpoints in multi-arm multi-stage clinical trials selecting all promising treatments

Jaki, T. & Magirr, D., 30/03/2013, In: Statistics in Medicine. 32, 7, p. 1150-1163 14 p.

Research output: Contribution to journal › Journal article › peer-review

Uptake of novel statistical methods for early phase clinical studies in the UK public sector

Jaki, T., 04/2013, In: Clinical Trials. 10, 2, p. 344-346 3 p.

Research output: Contribution to journal › Journal article › peer-review

Principles of dose finding studies in cancer: a comparison of trial designs

Jaki, T., Clive, S. & Weir, C., 05/2013, In: Cancer Chemotherapy and Pharmacology. 71, 5, p. 1107-1114 8 p.

Research output: Contribution to journal › Journal article › peer-review

Designing exploratory cancer trials using change in tumour size as primary endpoint

Jaki, T., Andre, V., Su, T-L. & Whitehead, J., 10/07/2013, In: Statistics in Medicine. 32, 15, p. 2544-2554 11 p.

Research output: Contribution to journal › Journal article › peer-review

Analysing malaria drug trials on a per individual or a per clone basis: a comparison of methods

Jaki, T., Parry, A., Winter, K. & Hastings, I., 30/07/2013, In: Statistics in Medicine. 32, 17, p. 3020-3038 19 p.

Research output: Contribution to journal › Journal article › peer-review

Differential effects of parental controls on adolescent substance use: for whom is the family most important?

Fagan, A. A., Van Horn, M. L., Hawkins, J. D. & Jaki, T., 09/2013, In: Journal of Quantitative Criminology. 29, 3, p. 347-368 22 p.

Research output: Contribution to journal › Journal article › peer-review

Multiplicity: discussion points from the PSI multiplicity expert group

Phillips, A., Fletcher, C., Atkinson, G., Channon, E., Douiri, A., Jaki, T., Maca, J., Morgan, D., Roger, J. H. & Terrill, P., 09/2013, In: Pharmaceutical Statistics. 12, 5, p. 255-259 5 p.

Research output: Contribution to journal › Journal article › peer-review

Planning multi-arm screening studies within the context of a drug development programme

Wason, J., Jaki, T. & Stallard, N., 10/09/2013, In: Statistics in Medicine. 32, 20, p. 3424-3435 12 p.

Research output: Contribution to journal › Journal article › peer-review

Statistical evaluation of toxicological assays: Dunnett or Williams test? − take both

Jaki, T. & Hothorn, L. A., 11/2013, In: Archives of Toxicology. 87, 11, p. 1901-1910 10 p.

Research output: Contribution to journal › Journal article › peer-review

Authors' reply to comments on "Estimation in AB/BA cross-over trials with application to bioequivalence studies with incomplete and complete data settings"

Jaki, T., Pallmann, P. & Wolfsegger, M. J., 30/12/2013, In: Statistics in Medicine. 32, 30, p. 5487-5488 2 p.

Research output: Contribution to journal › Comment/debate

Estimation in AB/BA cross-over trials with application to bioequivalence studies with incomplete and complete data designs

Jaki, T., Pallmann, P. & Wolfsegger, M. J., 30/12/2013, In: Statistics in Medicine. 32, 30, p. 5469-5483 15 p.

Research output: Contribution to journal › Journal article › peer-review

A hybrid method to estimate the minimum effective dose for monotone and non-monotone dose-response relationships

Wolfsegger, M. J., Gutjahr, G., Engl, W. & Jaki, T., 2014, In: Biometrics. 70, 1, p. 103-109 7 p.

Research output: Contribution to journal › Journal article › peer-review

Statistical evaluation of toxicological assays with zero or near-to-zero proportions or counts in the concurrent negative control group: a tutorial

Jaki, T., Kitsche, A. & Hothorn, L. A., 2014, In: JP Journal of Biostatistics. 11, 1, p. 1-32 32 p.

Research output: Contribution to journal › Journal article › peer-review

A comparison of methods for classifying samples as truly specific with confirmatory immunoassays

Jaki, T., Lawo, J-P., Wolfsegger, M. J., Allacher, P. & Horling, F., 25/01/2014, In: Journal of Pharmaceutical and Biomedical Analysis. 88, p. 27-35 9 p.

Research output: Contribution to journal › Journal article › peer-review

Flexible sequential designs for multi-arm clinical trials

Magirr, D., Stallard, N. & Jaki, T., 30/08/2014, In: Statistics in Medicine. 33, 19, p. 3269-3279 11 p.

Research output: Contribution to journal › Journal article › peer-review

Statistical approaches for the determination of cut points in anti-drug antibody bioassays

Schaarschmidt, F., Hofmann, M., Jaki, T., Gruen, B. & Hothorn, L. A., 03/2015, In: Journal of Immunological Methods. 418, p. 84-100 17 p.

Research output: Contribution to journal › Journal article › peer-review

Multi-arm clinical trials with treatment selection: what can be gained and at what price?

Jaki, T., 04/2015, In: Clinical Investigation. 5, 4, p. 393-399 7 p.

Research output: Contribution to journal › Journal article › peer-review

Adaptive clinical trials in tuberculosis: applications, challenges and solutions

Davis, G. R., Phillips, P. P. & Jaki, T., 1/06/2015, In: International Journal of Tuberculosis and Lung Disease. 19, 6, p. 626-634 9 p.

Research output: Contribution to journal › Journal article › peer-review

A practical design for a dual-agent dose-escalation trial that incorporates pharmacokinetic data

Cotterill, A., Lorand, D., Wang, J. & Jaki, T., 15/06/2015, In: Statistics in Medicine. 34, 13, p. 2138-2164 27 p.

Research output: Contribution to journal › Journal article › peer-review

Evaluating differential effects using regression interactions and regression mixture models

Van Horn, M. L., Jaki, T., Maysn, K., Howe, G., Feaster, D., Lamont, A. E., George, M. & Kim, M., 08/2015, In: Educational and Psychological Measurement. 75, 4, p. 677-714 38 p.

Research output: Contribution to journal › Journal article › peer-review

Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of Telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy

Pushpakom, S. P., Taylor, C., Kolamunnage-Dona, R., Spowart, C., Vora, J., Garcıa-Finana, M., Kemp, G. J., Whitehead, J., Jaki, T., Khoo, S., Williamson, P. & Pirmohamed, M., 15/10/2015, In: BMJ Open. 5, 10, 13 p., e009566.

Research output: Contribution to journal › Journal article › peer-review

Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function

Yeung, W. Y., Whitehead, J. R., Reigner, B., Beyer, U., Diack, C. & Jaki, T. F., 11/2015, In: Pharmaceutical Statistics. 14, 6, p. 479-487 9 p.

Research output: Contribution to journal › Journal article › peer-review

Using multilevel regression mixture models to identify level-1 heterogeneity in level-2 effects

Van Horn, M. L., Feng, Y., Kim, M., Lamont, A. E., Feaster, D. & Jaki, T., 2016, In: Structural Equation Modeling. 23, 2, p. 259-269 11 p.

Research output: Contribution to journal › Journal article › peer-review

Sample size reassessment and hypothesis testing in adaptive survival trials

Magirr, D., Jaki, T. F., Koenig, F. & Posch, M., 10/02/2016, In: PLoS ONE. 11, 2, 14 p., e0146465.

Research output: Contribution to journal › Journal article › peer-review

Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection

Jaki, T. & Hampson, L., 20/02/2016, In: Statistics in Medicine. 35, 4, p. 522-533 12 p.

Research output: Contribution to journal › Journal article › peer-review

Some recommendations for multi-arm multi-stage trials

Wason, J., Magirr, D., Law, M. & Jaki, T., 04/2016, In: Statistical Methods in Medical Research. 25, 2, p. 716-727 12 p.

Research output: Contribution to journal › Journal article › peer-review

A review of statistical designs for improving the efficiency of phase II studies in oncology

Wason, J. & Jaki, T., 06/2016, In: Statistical Methods in Medical Research. 25, 3, p. 1010-1021 12 p.

Research output: Contribution to journal › Journal article › peer-review

Impact of an equality constraint on the class-specific residual variances in regression mixtures: a Monte Carlo simulation study

Kim, M., Lamont, A. E., Jaki, T., Feaster, D., Howe, G. & Van Horn, M. L., 06/2016, In: Behavior Research Methods. 48, 2, p. 813-826 14 p.

Research output: Contribution to journal › Journal article › peer-review

Modeling predictors of latent classes in regression mixture models

Kim, M., Vermunt, J., Bakk, Z., Jaki, T. F. & Van Horn, M. L., 06/2016, In: Structural Equation Modeling. 23, 4, p. 601-614 14 p.

Research output: Contribution to journal › Journal article › peer-review

Why are two mistakes not worse than one? a proposal for controlling the expected number of false claims

Jaki, T. F. & Parry, A., 07/2016, In: Pharmaceutical Statistics. 15, 4, p. 362-367 6 p.

Research output: Contribution to journal › Journal article › peer-review

Understanding clinical prediction models as ‘innovations’: a mixed methods study in UK family practice

Brown, B., Cheraghi-Sohi, S., Jaki, T. F., Su, T-L., Buchan, I. & Sperrin, M., 9/08/2016, In: BMC Medical Informatics and Decision Making. 16, 13 p., 106.

Research output: Contribution to journal › Journal article › peer-review

Tilting the lasso by knowledge-based post-processing

Tharmaratnam, K., Sperrin, M., Jaki, T. F., Reppe, S. & Frigessi, A., 2/09/2016, In: BMC Bioinformatics. 17, 9 p., 344.

Research output: Contribution to journal › Journal article › peer-review

A false sense of security? can tiered approach be trusted to accurately classify immunogenicity samples?

Jaki, T. F., Allacher, P. & Horling, F., 5/09/2016, In: Journal of Pharmaceutical and Biomedical Analysis. 128, p. 166-173 8 p.

Research output: Contribution to journal › Journal article › peer-review

Clinical drug development in epilepsy revisited: a proposal for a new paradigm streamlined using extrapolation

Wadsworth, I., Jaki, T. F., Sills, G. J., Appleton, R., Cross, J. H., Marson, A. G., Martland, T., McLellan, A., Smith, P. E. M., Pellock, J. M. & Hampson, L. V., 11/2016, In: CNS Drugs. 30, 11, p. 1011-1017 7 p.

Research output: Contribution to journal › Journal article › peer-review

Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children

Hampson, L. V., Fisch, R., Van, L. M. & Jaki, T. F., 10/02/2017, In: Statistics in Medicine. 36, 3, p. 426-441 16 p.

Research output: Contribution to journal › Journal article › peer-review

Factorial versus multi-arm multi-stage designs for clinical trials with multiple treatments

Jaki, T. F. & Vasileiou, D., 20/02/2017, In: Statistics in Medicine. 36, 4, p. 563-580 8 p.

Research output: Contribution to journal › Journal article › peer-review

A Bayesian adaptive design for clinical trials in rare diseases

Williamson, F., Jacko, P., Villar, S. S. & Jaki, T. F., 09/2017, In: Computational Statistics and Data Analysis. 113, p. 136-153 17 p.

Research output: Contribution to journal › Journal article › peer-review

Estimation in multi-arm two-stage trials with treatment selection and time-to-event endpoint

Brueckner, M., Titman, A. C. & Jaki, T. F., 10/09/2017, In: Statistics in Medicine. 36, 20, p. 3137-3153 17 p.

Research output: Contribution to journal › Journal article › peer-review

Comparing sampling methods for pharmacokinetic studies using model averaged derived parameters

Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T., 30/11/2017, In: Statistics in Medicine. 36, 27, p. 4301-4315 15 p.

Research output: Contribution to journal › Journal article › peer-review

Simultaneous confidence regions for multivariate bioequivalence

Pallmann, P. S. & Jaki, T. F., 20/12/2017, In: Statistics in Medicine. 36, 29, p. 4585-4603 19 p.

Research output: Contribution to journal › Journal article › peer-review

Optimal Designs for Non-Compartmental Analysis of Pharmacokinetic Studies

Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T. F., 2018, In: Statistics in Biopharmaceutical Research. 10, 4, p. 255-263 9 p.

Research output: Contribution to journal › Journal article › peer-review

A review of statistical updating methods for clinical prediction models

Su, T-L., Jaki, T. F., Hickey, G., Buchan, I. & Sperrin, M., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 185-197 13 p.

Research output: Contribution to journal › Journal article › peer-review

Identification of Predicted Individual Treatment Effects (PITE) in randomized clinical trials

Lamont, A. E., Lyons, M., Jaki, T. F., Stuart, E. A., Feaster, D., Ishwaran, H., Tharmaratnam, K. & Van Horn, M. L., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 142-157 16 p.

Research output: Contribution to journal › Journal article › peer-review

Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods

Wadsworth, I., Hampson, L. V. & Jaki, T. F., 1/02/2018, In: Statistical Methods in Medical Research. 27, 2, p. 398-413 16 p.

Research output: Contribution to journal › Journal article › peer-review

A review of the deterministic and diffusion approximations for stochastic chemical reaction networks

Mozgunov, P., Beccuti, M., Horvath, A., Jaki, T. F., Sirovich, R. & Bibbona, E., 04/2018, In: Reaction Kinetics, Mechanisms and Catalysis. 123, 2, p. 289-312 24 p.

Research output: Contribution to journal › Journal article › peer-review

An information-theoretic Phase I/II design for molecularly targeted agents that does not require an assumption of monotonicity

Mozgunov, P. & Jaki, T. F., 15/06/2018, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 68, 2, p. 347-367 21 p.

Research output: Contribution to journal › Journal article › peer-review

Model selection based on combined penalties for biomarker identification

Vradi, E., Brannath, W., Jaki, T. & Vonk, R., 4/07/2018, In: Journal of Biopharmaceutical Statistics. 28, 4, p. 735-749 15 p.

Research output: Contribution to journal › Journal article › peer-review

A proposal for a new PhD level curriculum on quantitative methods for drug development

Jaki, T. F., Gordon, A., Forster, P. S., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L. V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A. C., Vonk, R. & Koenig, F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 593-606 14 p.

Research output: Contribution to journal › Journal article › peer-review

Dose-escalation strategies which utilise subgroup information

Cotterill, A. & Jaki, T. F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 414-436 13 p.

Research output: Contribution to journal › Journal article › peer-review

Performance of different clinical trial designs to evaluate treatments during an epidemic

Brueckner, M., Titman, A. C., Jaki, T. F., Rojek, A. & Horby, P. W., 11/09/2018, In: PLoS ONE. 13, 9, 19 p., e0203387.

Research output: Contribution to journal › Journal article › peer-review

Subgroup identification in clinical trials via the predicted individual treatment effect

Ballarini, N. M., Rosenkranz, G. K., Jaki, T., König, F. & Posch, M., 18/10/2018, In: PLoS ONE. 13, 10, 22 p., e0205971.

Research output: Contribution to journal › Journal article › peer-review

Randomized dose-escalation designs for drug combination cancer trials with immunotherapy

Mozgunov, P., Jaki, T. F. & Paoletti, X., 23/10/2018, In: Journal of Biopharmaceutical Statistics. 29, 2, p. 359-377 19 p.

Research output: Contribution to journal › Journal article › peer-review

Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design

Dimairo, M., Coates, E., Pallmann, P., Todd, S., Julious, S. A., Jaki, T., Wason, J., Mander, A. P., Weir, C. J., Koenig, F., Walton, M. K., Biggs, K., Nicholl, J., Hamasaki, T., Proschan, M. A., Scott, J. A., Ando, Y., Hind, D. & Altman, D. G., 16/11/2018, In: BMC Medicine. 16, 1, 20 p.

Research output: Contribution to journal › Journal article › peer-review

Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study

Jaki, T. & Wason, J. M. S., 27/11/2018, In: BMC Cardiovascular Disorders. 18, 1, 8 p., 215.

Research output: Contribution to journal › Journal article › peer-review

Design and estimation in clinical trials with subpopulation selection

Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T. F., 20/12/2018, In: Statistics in Medicine. 37, 29, p. 4335-4352 18 p.

Research output: Contribution to journal › Journal article › peer-review

An alternative method to analyse the Biomarker-strategy design

Kunz, C. U., Jaki, T. F. & Stallard, N., 30/12/2018, In: Statistics in Medicine. 37, 30, p. 4636-4651 16 p.

Research output: Contribution to journal › Journal article › peer-review

Confidence regions for treatment effects in subgroups in biomarker stratified designs

Wan, F., Kunz, C. U. & Jaki, T. F., 1/01/2019, In: Biometrical Journal. 61, 1, p. 27-39 13 p.

Research output: Contribution to journal › Journal article › peer-review

Editorial for the MCP 2017 Special Issue

Cui, X., Hsu, J. C. & Jaki, T., 11/01/2019, In: Biometrical Journal. 61, 1, p. 7 1 p.

Research output: Contribution to journal › Editorial › peer-review

How to design a dose-finding study using the continual reassessment method

Wheeler, G. M., Mander, A. P., Bedding, A., Brock, K., Cornelius, V., Grieve, A. P., Jaki, T., Love, S. B., Odondi, L., Weir, C. J., Yap, C. & Bond, S. J., 18/01/2019, In: BMC Medical Research Methodology. 19, 1, 15 p., 18.

Research output: Contribution to journal › Journal article › peer-review

The R package MAMS for designing multi-arm multi-stage clinical trials

Jaki, T. F., Pallmann, P. S. & Magirr, D., 31/01/2019, In: Journal of Statistical Software. 88, 4, 25 p.

Research output: Contribution to journal › Journal article › peer-review

Instrumental variable estimation in semi-parametric additive hazards models

Brueckner, M., Titman, A. C. & Jaki, T. F., 1/03/2019, In: Biometrics. 75, 1, p. 110-120 11 p.

Research output: Contribution to journal › Journal article › peer-review

The effects of sample size on the estimation of regression mixture models

Jaki, T. F., Kim, M., Lamont, A. E., George, M., Feaster, D. & Van Horn, M. L., 1/04/2019, In: Educational and Psychological Measurement. 79, 2, p. 358-384 27 p.

Research output: Contribution to journal › Journal article › peer-review

Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593-606, Sep/Oct 2018., DOI https://doi.org/10.1002/pst.1873

Jaki, T., Gordon, A., Forster, P., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L. V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A., Vonk, R. & Koenig, F., 1/05/2019, In: Pharmaceutical Statistics. 18, 3, p. 284-286 3 p.

Research output: Contribution to journal › Letter › peer-review

Model-Based dose escalation Designs in R with crmPack

Bové, D. S., Yeung, W. Y., Palermo, G. & Jaki, T., 13/06/2019, In: Journal of Statistical Software. 89, 10, 22 p.

Research output: Contribution to journal › Journal article › peer-review

Bayesian sequential integration within a preclinical pharmacokinetic and pharmacodynamic modeling framework: Lessons learned

La Gamba, F., Jacobs, T., Geys, H., Jaki, T., Serroyen, J., Ursino, M., Russu, A. & Faes, C., 1/07/2019, In: Pharmaceutical Statistics. 18, 4, p. 486-506 21 p.

Research output: Contribution to journal › Journal article › peer-review

A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay

Vradi, E., Jaki, T. F., Vonk, R. & Brannath, W., 1/08/2019, In: Statistical Methods in Medical Research. 28, 8, p. 2538-2556 19 p.

Research output: Contribution to journal › Journal article › peer-review

A novel measure of drug benefit–risk assessment based on Scale Loss Score

Saint-Hilary, G., Robert, V., Gasparini, M., Jaki, T. F. & Mozgunov, P., 1/09/2019, In: Statistical Methods in Medical Research. 28, 9, p. 2738-2753 16 p.

Research output: Contribution to journal › Journal article › peer-review

Loss Functions in Restricted Parameter Spaces and Their Bayesian Applications

Mozgunov, P., Jaki, T. F. & Gasparini, M., 3/10/2019, In: Journal of Applied Statistics. 46, 13, p. 2314-2337 24 p.

Research output: Contribution to journal › Journal article › peer-review