Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: Study protocol for a phase 3 randomized, double-blind, placebo-controlled, multicentre trial

Wang, Y., Zhou, F., Zhang, D., Zhao, J., Du, R., Hu, Y., Cheng, Z., Gao, L., Jin, Y., Luo, G., Fu, S., Lu, Q., Du, G., Wang, K., Lu, Y., Fan, G., Zhang, Y., Liu, Y., Ruan, S., Liu, W., & 5 othersJaki, T., Hayden, F. G., Horby, P. W., Cao, B. & Wang, C., 24/05/2020, In: Trials. 21, 1, 11 p., 422.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimation of treatment effects following a sequential trial of multiple treatments

Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

Wang, Y., Zhang, D., Du, G., Du, R., Zhao, J., Jin, Y., Fu, S., Gao, L., Cheng, Z., Lu, Q., Hu, Y., Luo, G., Wang, K., Lu, Y., Li, H., Wang, S., Ruan, S., Yang, C., Mei, C., Ding, D., & 25 othersWu, F., Tang, X., Ye, X., Ye, Y., Liu, B., Yang, J., Yin, W., Wang, A., Fan, G., Zhou, F., Liu, Z., Gu, X., Xu, J., Shang, L., Zhang, Y., Cao, L., Guo, T., Wan, Y., Qin, H., Jiang, Y., Jaki, T., Hayden, F. G., Horby, P. W., Cao, B. & Wang, C., 16/05/2020, In: The Lancet. p. 1569-1578 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy

Pushpakom, S., Kolamunnage-Dona, R., Taylor, C., Foster, T., Spowart, C., García-Fiñana, M., Kemp, G. J., Jaki, T., Khoo, S., Williamson, P. & Pirmohamed, M., 15/05/2020, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 70, 10, p. 2062-2072 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A comparison of stochastic programming methods for portfolio level decision-making

Graham, E., Jaki, T. & Harbron, C., 1/05/2020, In: Journal of Biopharmaceutical Statistics. 30, 3, p. 405-429 25 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Creating a framework for conducting randomized clinical trials during disease outbreaks

Dean, N. E., Gsell, P-S., Brookmeyer, R., Crawford, F. W., Donnelly, C. A., Ellenberg, S. S., Fleming, T. R., Halloran, E. M., Horby, P., Jaki, T., Krause, P. R., Longini, I. M., Mulangu, S., Muyembe-Tamfum, J-J., Nason, M. C., Smith, P. G., Wang, R., Henao-Restrepo, A. M. & De Gruttola, V., 2/04/2020, In: New England Journal of Medicine. 382, 14, p. 1366-1369 4 p.

Research output: Contribution to Journal/Magazine › Editorial › peer-review

A benchmark for dose finding studies with continuous outcomes

Mozgunov, P., Jaki, T. F. & Paoletti, X., 1/04/2020, In: Biostatistics. 21, 2, p. 189–201 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

Pallmann, P., Wan, F., Mander, A. P., Wheeler, G. M., Yap, C., Clive, S., Hampson, L. V. & Jaki, T., 1/04/2020, In: Clinical Trials. 17, 2, p. 147-156 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Repeated measures regression mixture models

Kim, M., Van Horn, M. L., Jaki, T., Vermunt, J., Feaster, D., Lichstein, K. L., Taylor, D. J., Riedel, B. W. & Bush, A. J., 1/04/2020, In: Behavior Research Methods. 52, 2, p. 591-606 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Improving safety of the continual reassessment method via a modified allocation rule

Mozgunov, P. & Jaki, T., 30/03/2020, In: Statistics in Medicine. 39, 7, p. 906-922 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review