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    Rights statement: This is the peer reviewed version of the following article: Bowring, D. L., Totsika, V., Hastings, R. P., Toogood, S., and McMahon, M. (2017) Prevalence of psychotropic medication use and association with challenging behaviour in adults with an intellectual disability. A total population study. Journal of Intellectual Disability Research, 61: 604–617. doi: 10.1111/jir.12359 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/jir.12359/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.

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Prevalence of psychotropic medication use and association with challenging behaviour in adults with an intellectual disability: a total population study

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Published
  • Darren Bowring
  • Vasiliki Totsika
  • Richard Hastings
  • Sandy Toogood
  • Martin McMahon
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<mark>Journal publication date</mark>06/2017
<mark>Journal</mark>Journal of Intellectual Disability Research
Issue number6
Volume61
Number of pages14
Pages (from-to)604-617
Publication StatusPublished
Early online date16/01/17
<mark>Original language</mark>English

Abstract

Background

There is a high prevalence of psychotropic medication use in adults with Intellectual Disabilities (ID), often in the absence of psychiatric disorder, also associated with challenging behaviour. Previous research has focused on specific sample frames or data from primary care providers. There is also a lack of consistency in the definition of challenging behaviour used.

Methods

We adopted a total population sampling method. Medication data on 265 adults with ID were classified according to the Anatomical Therapeutic Chemical classification system. The Behaviour Problems Inventory – short form classified challenging behaviours. We examined the association between challenging behaviour and the use of psychotropic medication, and whether any association would still be present after accounting for socio-demographic and clinical characteristics.

Results

70.57% of adults with ID were prescribed at least one class of any medication (mean per person =2.62; range 0–14). Psychotropic medications were used by 37.73% of participants with antipsychotics the commonest type used by 21.89% of individuals. Polypharmacy and high dosages were common. Generalised Linear Models indicated significant associations between psychotropic medication and the presence of a psychiatric diagnosis, challenging behaviour, older age and type of residence. Male gender was additionally associated with antipsychotic medication.

Conclusions

The use of a total population sample identified via multiple routes is less likely to overestimate prevalence rates of medication use. Current challenging behaviour was a predictor of medication use after controlling for other variables. Data indicate that there may be differences in prescribing patterns associated with different topographies of challenging behaviours.

Bibliographic note

This is the peer reviewed version of the following article: Bowring, D. L., Totsika, V., Hastings, R. P., Toogood, S., and McMahon, M. (2017) Prevalence of psychotropic medication use and association with challenging behaviour in adults with an intellectual disability. A total population study. Journal of Intellectual Disability Research, 61: 604–617. doi: 10.1111/jir.12359 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/jir.12359/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.