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High-affinity ultivalent DNA binding by using low-molecular-weight dendrons

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<mark>Journal publication date</mark>22/04/2005
<mark>Journal</mark>Angewandte Chemie International Edition
Issue number17
Volume44
Number of pages4
Pages (from-to)2556-2559
StatePublished
Original languageEnglish

Abstract

Nine spermines are better than one: Compound G2 exhibits high-affinity, salt-independent DNA binding as a consequence of the spermine array on its surface. Comparison with smaller dendrons and model compounds indicates a clear multivalency effect on binding.