The handling and braking responses of a heavy vehicle equipped with a cross-axle fluidically-coupled hydropneumatic suspension concept are investigated. The proposed fluidically-coupled suspension is conceived by diagonally interconnecting different hydraulic fluid chambers of the four suspension struts of the vehicle. The analytical formulations of suspension forces are derived based on fluid flows through the couplings and damping valves. A generalized full-vehicle model is developed and validated to evaluate the handling and braking responses to two critical vehicle maneuvers: (i) braking-in-a-turn; and (ii) split-μ straight-line braking. The responses of the vehicle model with the coupled suspension are compared with those of the uncoupled suspension under various inputs to demonstrate the potential benefits of the proposed cross-axle fluidic coupling of the suspension struts.