Research output: Contribution to Journal/Magazine › Journal article › peer-review
| <mark>Journal publication date</mark> | 19/08/2011 |
|---|---|
| <mark>Journal</mark> | Organic Letters |
| Issue number | 16 |
| Volume | 13 |
| Number of pages | 4 |
| Pages (from-to) | 4264-4267 |
| Publication Status | Published |
| <mark>Original language</mark> | English |
An asymmetric decarboxylative palladium-catalyzed allylation of alkyl- and aryl-substituted oxindoles has been developed, enabling the installation of an all-carbon quaternary chiral center at the oxindole 3-position in excellent yields and good to excellent enantioselectivity. An intriguing substrate-dependent reversal in stereoselectivity has been observed, whereby the size of the substituent determines the facial selectivity in the allylation step.