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Bioactive gyroid scaffolds formed by sacrificial templating of nanocellulose and nanochitin hydrogels as instructive platforms for biomimetic tissue engineering

Research output: Contribution to journalJournal article

Published
  • Jose Guillermo Torres-Rendon
  • Tim Femmer
  • Laura De Laporte
  • Thomas Tigges
  • Khoshrow Rahimi
  • Felix Gremse
  • Sara Zafarnia
  • Wiltrud Lederle
  • Shinsuke Ifuku
  • Matthias Wessling
  • John G. Hardy
  • Andreas Walther
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<mark>Journal publication date</mark>2015
<mark>Journal</mark>Advanced Materials
Issue number19
Volume27
Number of pages7
Pages (from-to)2989-2995
<mark>State</mark>Published
Early online date2/04/15
<mark>Original language</mark>English

Abstract

A sacrificial templating process using lithographically printed minimal surface structures allows complex de novo geometries of delicate hydrogel materials. The hydrogel scaffolds based on cellulose and chitin nanofibrils show differences in terms of attachment of human mesenchymal stem cells, and allow their differentiation into osteogenic outcomes. The approach here serves as a first example toward designer hydrogel scaffolds viable for biomimetic tissue engineering.