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Towards organic electronic materials for electrically stimulated gene delivery: nanoparticles for biotherapeutic therapy

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Publication date07/2015
Host publicationNanoparticles for biotherapeutic delivery
EditorsJoshua D. Ramsey, M. Laird Forrest
PublisherFuture Science Group
Pages58-70
Number of pages13
Volume2
ISBN (Electronic)9781910420430
Original languageEnglish

Abstract

The cell-specific delivery of polynucleic acids (e.g., DNA, RNA), gene therapy, has the potential to treat various diseases. In this chapter we discuss the use of organic electronic materials as non-viral gene delivery vectors and the great potential for electrochemically triggered gene delivery. We highlight some examples in this chapter based on fullerenes (bucky balls and carbon nanotubes), graphenes and electroactive polymers, particularly those that include experiments in vivo.