Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
<mark>Journal publication date</mark> | 1/02/2015 |
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<mark>Journal</mark> | Catalysis Science and Technology |
Issue number | 2 |
Volume | 5 |
Number of pages | 7 |
Pages (from-to) | 690-696 |
Publication Status | Published |
Early online date | 11/09/14 |
<mark>Original language</mark> | English |
Proline has been grafted onto silica supports in a single step by reacting trans-4-hydroxy-L-proline with chloropropyl tethers, without the use of protecting groups for the proline amine and carboxylic acid functional groups. The resulting catalysts have been characterised to show that grafting is through reaction with the 4-hydroxy group. The catalysts have been tested in an asymmetric aldol reaction, and shown to be both more active and more enantioselective than equivalent catalysts prepared using a protection/deprotection route for the proline grafting step.