Rights statement: This is the peer reviewed version of the following article: M. Jakoobi, N. Halcovitch, G. F. S. Whitehead, A. G. Sergeev, Angew. Chem. Int. Ed. 2017, 56, 3266 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/anie.201611409/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Accepted author manuscript, 315 KB, PDF document
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Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
<mark>Journal publication date</mark> | 13/03/2017 |
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<mark>Journal</mark> | Angewandte Chemie International Edition |
Issue number | 12 |
Volume | 56 |
Number of pages | 4 |
Pages (from-to) | 3266-3269 |
Publication Status | Published |
Early online date | 17/02/17 |
<mark>Original language</mark> | English |
We report an unprecedented selective cleavage of aromatic C-C bonds through the insertion of well-defined iridium complexes into the aromatic ring of simple alkylarenes. The insertion occurs at 50-100 °C without the activation of weaker C-H and C-C bonds and gives unique metallacycles in high yields. Key to the success of this approach is metal-induced deformation of the arene ring, which creates temporary ring strain and promotes direct and selective insertion of the metal into the otherwise inert arene ring C-C bonds.