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Peptide-directed assembly of functional supramolecular polymers for biomedical applications: electroactive molecular tongue-twisters (oligoalanine-oligoaniline-oligoalanine) for electrochemically enhanced drug delivery

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  • John G. Hardy
  • Megan N. Amend
  • Sydney Geissler
  • Vincent M. Lynch
  • Christine E. Schmidt
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<mark>Journal publication date</mark>8/06/2015
<mark>Journal</mark>Journal of Materials Chemistry B
Issue number25
Volume3
Number of pages5
Pages (from-to)5005-5009
<mark>State</mark>Published
<mark>Original language</mark>English

Abstract

We report the preparation and characterization of films of electroactive supramolecular polymers based on non-electroactive oligoalanines and electroactive oligoanilines. Fibroblasts adhered to and proliferated on the films, and the delivery of the clinically relevant anti-inflammatory drug dexamethasone phosphate could be enhanced upon the application of an electrical stimulus.

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This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. This journal is © The Royal Society of Chemistry 2015