This article explores the role of non-governmental organizations (NGOs) in the making of global tourism destinations. First, it draws together diverse insights in order to substantiate the importance of NGOs in the making of global tourism destinations and, second, it empirically highlights the role of NGOs in the (re)making of one particular destination: “destino Guatemala”. NGOs in La Antigua Guatemala are increasingly engaging with tourism as a NGO resource. In focusing on the NGO touristic practice of hosting storytelling events/activities in Antigua, some of which come to form virtual/actual “poverty tours”, the article argues that while Antigua NGOs develop and host these poverty tours as a means of moving “hearts and wallets”, they are doing considerably more. Most notably, they are helping to (re)make Guatemala into a “development tourism destination”.