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Gene delivery with organic electronic biomaterials

Research output: Contribution to journalLiterature review

Published
<mark>Journal publication date</mark>09/2017
<mark>Journal</mark>Current Pharmaceutical Design
Issue number24
Volume23
Number of pages12
Pages (from-to)3614-3625
StatePublished
Early online date19/07/17
Original languageEnglish

Abstract

Gene therapy may be capable of treating a variety of diseases, a prerequisite of which is the successful delivery of polynucleic acids (e.g., DNA, RNA) to a patient’s cells. Delivery can be achieved technologically (e.g., using electroporation), using viruses (natural gene delivery vectors) or non-viral vectors (e.g., lipids, nanoparticles, polymers). This article aims to give the reader an overview of the use of organic electronic materials (i.e., fullerenes, graphenes and conjugated polymers) as non-viral gene delivery vectors.

Bibliographic note

© 2017 Bentham Science Publishers