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Home > Research > Publications & Outputs > 3-Chloromethylpyridyl Bipyridine fac Tricarbony...
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3-Chloromethylpyridyl Bipyridine fac Tricarbonyl Rhenium: A Thiol-Reactive Lumophore for Fluorescence Microscopy Accumulates In Mitochondria

Research output: Contribution to journalJournal article

Published

  • Angelo J. Amoroso
  • Richard J. Arthur
  • Michael Coogan
  • Jonathan B. Court
  • Vanesa Fernandez-Moreira
  • Anthony J. Hayes
  • David Lloyd
  • Coralie Millet
  • Simon J. A. Pope
Journal publication date2008
JournalNew Journal of Chemistry
Journal number7
Volume32
Number of pages16
Pages1097-1102
Original languageEnglish

Abstract

The 3-chloromethylpyridyl bipyridine fac tricarbonyl rhenium cation is a thiol-reactive luminescent agent with a long luminescence lifetime and large Stokes shift that is demonstrated by co-localisation studies to accumulate in mitochondria. This represents the first application of a 3MLCT luminescent agent for the specific targeting of a biological entity in imaging.