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3-Chloromethylpyridyl Bipyridine fac Tricarbonyl Rhenium: A Thiol-Reactive Lumophore for Fluorescence Microscopy Accumulates In Mitochondria

Research output: Contribution to journalJournal article


  • Angelo J. Amoroso
  • Richard J. Arthur
  • Michael Coogan
  • Jonathan B. Court
  • Vanesa Fernandez-Moreira
  • Anthony J. Hayes
  • David Lloyd
  • Coralie Millet
  • Simon J. A. Pope
<mark>Journal publication date</mark>2008
<mark>Journal</mark>New Journal of Chemistry
Issue number7
Number of pages16
Pages (from-to)1097-1102
<mark>Original language</mark>English


The 3-chloromethylpyridyl bipyridine fac tricarbonyl rhenium cation is a thiol-reactive luminescent agent with a long luminescence lifetime and large Stokes shift that is demonstrated by co-localisation studies to accumulate in mitochondria. This represents the first application of a 3MLCT luminescent agent for the specific targeting of a biological entity in imaging.