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    Rights statement: © 2013 Jones et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A randomised controlled trial of time limited CBT informed psychological therapy for anxiety in bipolar disorder

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A randomised controlled trial of time limited CBT informed psychological therapy for anxiety in bipolar disorder. / Jones, Steven; McGrath, Elly; Hampshire, Kay et al.
In: BMC Psychiatry, Vol. 13, 54, 2013.

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@article{181f6ec0a76d4eef822dc788ad228c83,
title = "A randomised controlled trial of time limited CBT informed psychological therapy for anxiety in bipolar disorder",
abstract = "BACKGROUND: Anxiety comorbidity is common in bipolar disorder and is associated with worse treatment outcomes, greater risk of self harm, suicide and substance misuse. To date however there have been no psychological interventions specifically designed to address this problem. The primary objective of this trial is to establish the acceptability and feasibility of a new integrated intervention for anxiety in bipolar disorder designed in collaboration with individuals with personal experience of both problems.METHODS AND DESIGN: Single blind randomised controlled trials to assess the feasibility and acceptability of a time limited CBT informed psychological intervention for anxiety in bipolar disorder (AIBD) compared with treatment as usual. Participants will be recruited from across the North West of England from specialist mental health services and through primary care and self referral. The primary outcome of the study is the feasibility and acceptability of AIBD assessed by recruitment to target and retention to follow-up, as well as absence of untoward incidents associated with AIBD. We will also estimate the effect size of the impact of the intervention on anxiety and mood outcomes, as well as calculate preliminary estimates of cost-effectiveness and investigate potential mechanisms for this (stigma, self appraisal and stability of social rhythms).DISCUSSION: This is the first trial of an integrated intervention for anxiety in bipolar disorder. It is of interest to researchers involved in the development of new therapies for bipolar disorder as well as indicating the wider potential for evaluating approaches to the treatment of comorbidity in severe mental illness.",
keywords = "Anxiety, Bipolar Disorder, Cognitive Therapy, Cost-Benefit Analysis, Humans, Patient Compliance, Physician-Patient Relations, Psychiatric Status Rating Scales, Psychotherapy, Brief, Quality of Life, Questionnaires, Single-Blind Method, Treatment Outcome",
author = "Steven Jones and Elly McGrath and Kay Hampshire and Rebecca Owen and Lisa Riste and Chris Roberts and Linda Davies and Debbie Mayes",
note = "{\textcopyright} 2013 Jones et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.",
year = "2013",
doi = "10.1186/1471-244X-13-54",
language = "English",
volume = "13",
journal = "BMC Psychiatry",
issn = "1471-244X",
publisher = "NLM (Medline)",

}

RIS

TY - JOUR

T1 - A randomised controlled trial of time limited CBT informed psychological therapy for anxiety in bipolar disorder

AU - Jones, Steven

AU - McGrath, Elly

AU - Hampshire, Kay

AU - Owen, Rebecca

AU - Riste, Lisa

AU - Roberts, Chris

AU - Davies, Linda

AU - Mayes, Debbie

N1 - © 2013 Jones et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PY - 2013

Y1 - 2013

N2 - BACKGROUND: Anxiety comorbidity is common in bipolar disorder and is associated with worse treatment outcomes, greater risk of self harm, suicide and substance misuse. To date however there have been no psychological interventions specifically designed to address this problem. The primary objective of this trial is to establish the acceptability and feasibility of a new integrated intervention for anxiety in bipolar disorder designed in collaboration with individuals with personal experience of both problems.METHODS AND DESIGN: Single blind randomised controlled trials to assess the feasibility and acceptability of a time limited CBT informed psychological intervention for anxiety in bipolar disorder (AIBD) compared with treatment as usual. Participants will be recruited from across the North West of England from specialist mental health services and through primary care and self referral. The primary outcome of the study is the feasibility and acceptability of AIBD assessed by recruitment to target and retention to follow-up, as well as absence of untoward incidents associated with AIBD. We will also estimate the effect size of the impact of the intervention on anxiety and mood outcomes, as well as calculate preliminary estimates of cost-effectiveness and investigate potential mechanisms for this (stigma, self appraisal and stability of social rhythms).DISCUSSION: This is the first trial of an integrated intervention for anxiety in bipolar disorder. It is of interest to researchers involved in the development of new therapies for bipolar disorder as well as indicating the wider potential for evaluating approaches to the treatment of comorbidity in severe mental illness.

AB - BACKGROUND: Anxiety comorbidity is common in bipolar disorder and is associated with worse treatment outcomes, greater risk of self harm, suicide and substance misuse. To date however there have been no psychological interventions specifically designed to address this problem. The primary objective of this trial is to establish the acceptability and feasibility of a new integrated intervention for anxiety in bipolar disorder designed in collaboration with individuals with personal experience of both problems.METHODS AND DESIGN: Single blind randomised controlled trials to assess the feasibility and acceptability of a time limited CBT informed psychological intervention for anxiety in bipolar disorder (AIBD) compared with treatment as usual. Participants will be recruited from across the North West of England from specialist mental health services and through primary care and self referral. The primary outcome of the study is the feasibility and acceptability of AIBD assessed by recruitment to target and retention to follow-up, as well as absence of untoward incidents associated with AIBD. We will also estimate the effect size of the impact of the intervention on anxiety and mood outcomes, as well as calculate preliminary estimates of cost-effectiveness and investigate potential mechanisms for this (stigma, self appraisal and stability of social rhythms).DISCUSSION: This is the first trial of an integrated intervention for anxiety in bipolar disorder. It is of interest to researchers involved in the development of new therapies for bipolar disorder as well as indicating the wider potential for evaluating approaches to the treatment of comorbidity in severe mental illness.

KW - Anxiety

KW - Bipolar Disorder

KW - Cognitive Therapy

KW - Cost-Benefit Analysis

KW - Humans

KW - Patient Compliance

KW - Physician-Patient Relations

KW - Psychiatric Status Rating Scales

KW - Psychotherapy, Brief

KW - Quality of Life

KW - Questionnaires

KW - Single-Blind Method

KW - Treatment Outcome

U2 - 10.1186/1471-244X-13-54

DO - 10.1186/1471-244X-13-54

M3 - Journal article

C2 - 23414176

VL - 13

JO - BMC Psychiatry

JF - BMC Psychiatry

SN - 1471-244X

M1 - 54

ER -