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A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

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A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran. / Twyman, Lance J.; Allsop, David.
In: Tetrahedron Letters, Vol. 40, No. 52, 12.1999, p. 9383-9384.

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Twyman LJ, Allsop D. A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran. Tetrahedron Letters. 1999 Dec;40(52):9383-9384. doi: 10.1016/S0040-4039(99)02030-4

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@article{5b45400a0b814e21bd53046455dfe1d5,
title = "A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.",
abstract = "A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid, which is thought to be the underlying cause of Alzheimer's disease, is described. A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid protein is described.",
keywords = "Benzofurans, heterocyclic, intramolecular Wittig reaction, β-amyloid, Alzheimer's disease",
author = "Twyman, {Lance J.} and David Allsop",
year = "1999",
month = dec,
doi = "10.1016/S0040-4039(99)02030-4",
language = "English",
volume = "40",
pages = "9383--9384",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd",
number = "52",

}

RIS

TY - JOUR

T1 - A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

AU - Twyman, Lance J.

AU - Allsop, David

PY - 1999/12

Y1 - 1999/12

N2 - A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid, which is thought to be the underlying cause of Alzheimer's disease, is described. A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid protein is described.

AB - A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid, which is thought to be the underlying cause of Alzheimer's disease, is described. A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid protein is described.

KW - Benzofurans

KW - heterocyclic

KW - intramolecular Wittig reaction

KW - β-amyloid

KW - Alzheimer's disease

U2 - 10.1016/S0040-4039(99)02030-4

DO - 10.1016/S0040-4039(99)02030-4

M3 - Journal article

VL - 40

SP - 9383

EP - 9384

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 52

ER -