TY - JOUR

T1 - Activity of antibiotics used in human medicine for Campylobacter jejuni isolated from farm animals and their environment in Lancashire, UK.

AU - Piddock, Laura J. V.

AU - Ricci, V.

AU - Stanley, K.

AU - Jones, Keith

PY - 2000/8

Y1 - 2000/8

N2 - A retrospective study of 96 Campylobacter jejuni isolated from farm animals and the environment showed that most were less susceptible than the NCTC type strain to nalidixic acid (MICs 4–32 mg/L), ciprofloxacin (MICs 1–2 mg/L) and erythromycin (MICs 16–64 mg/L), but had similar susceptibility to tetracycline (MICs 4–8 mg/L) and kanamycin (MICs 4–8 mg/L). None had the high MICs of ciprofloxacin (>32 mg/L) or erythromycin (1024 mg/L) typically associated with clinical resistance in this species. Some farms used antimicrobial agents, but there was no obvious association between the use of agents and the susceptibility of the isolates.

AB - A retrospective study of 96 Campylobacter jejuni isolated from farm animals and the environment showed that most were less susceptible than the NCTC type strain to nalidixic acid (MICs 4–32 mg/L), ciprofloxacin (MICs 1–2 mg/L) and erythromycin (MICs 16–64 mg/L), but had similar susceptibility to tetracycline (MICs 4–8 mg/L) and kanamycin (MICs 4–8 mg/L). None had the high MICs of ciprofloxacin (>32 mg/L) or erythromycin (1024 mg/L) typically associated with clinical resistance in this species. Some farms used antimicrobial agents, but there was no obvious association between the use of agents and the susceptibility of the isolates.

U2 - 10.1093/jac/46.2.303

DO - 10.1093/jac/46.2.303

M3 - Journal article

VL - 46

SP - 303

EP - 306

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

SN - 1460-2091

IS - 2

ER -