Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Analysis of Recombination in Campylobacterjejuni from MLST Population Data.
AU - Fearnhead, Paul
AU - Smith, Nick G. C.
AU - Barrigas, Mishele
AU - Fox, Andrew
AU - French, Nigel
PY - 2005/9
Y1 - 2005/9
N2 - We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km2 study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225–750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.
AB - We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km2 study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225–750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.
KW - Bacteria - Campylobacter - Helicobacter - MLST - Recombination rate - Recombination tract length
U2 - 10.1007/s00239-004-0316-0
DO - 10.1007/s00239-004-0316-0
M3 - Journal article
VL - 61
SP - 333
EP - 340
JO - Journal of Molecular Evolution
JF - Journal of Molecular Evolution
SN - 0022-2844
IS - 3
ER -