Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Boron for tissue regeneration-it’s loading into chitosan/collagen hydrogels and testing on chorioallantoic membrane to study the effect on angiogenesis
AU - Ahtzaz, S.
AU - Sher Waris, T.
AU - Shahzadi, L.
AU - Anwar Chaudhry, A.
AU - Ur Rehman, I.
AU - Yar, M.
PY - 2020/3/31
Y1 - 2020/3/31
N2 - In the current study, boric acid loaded chitosan (CS) and collagen-based hydrogels were prepared. Hydrogels with four different boric acid concentrations were prepared; control hydrogel (without boric acid), and a hydrogel having boric acid 50 mg (B50), 250 mg boric acid (B250) and 500 mg boric acid (B500). Internal morphology of hydrogel was determined by performing scanning electron microscopy (SEM). Internal linkages of functional groups were confirmed by Fourier transform infrared spectroscopy (FT-IR). The pro-angiogenic potential of these materials was explored in chorioallantoic membrane (CAM) assay and 50 mg boric acid (B50) based hydrogel showed comparatively higher angiogenesis.
AB - In the current study, boric acid loaded chitosan (CS) and collagen-based hydrogels were prepared. Hydrogels with four different boric acid concentrations were prepared; control hydrogel (without boric acid), and a hydrogel having boric acid 50 mg (B50), 250 mg boric acid (B250) and 500 mg boric acid (B500). Internal morphology of hydrogel was determined by performing scanning electron microscopy (SEM). Internal linkages of functional groups were confirmed by Fourier transform infrared spectroscopy (FT-IR). The pro-angiogenic potential of these materials was explored in chorioallantoic membrane (CAM) assay and 50 mg boric acid (B50) based hydrogel showed comparatively higher angiogenesis.
KW - Angiogenesis
KW - boron loaded hydrogel
KW - chitosan/collagen hydrogel
KW - tissue regeneration
KW - Boride coatings
KW - Boron
KW - Chitosan
KW - Fourier transform infrared spectroscopy
KW - Hydrogels
KW - Scanning electron microscopy
KW - Tissue
KW - Tissue regeneration
KW - Acid concentrations
KW - Chorio-allantoic membranes
KW - Chorioallantoic membrane assays
KW - Fourier transform infra red (FTIR) spectroscopy
KW - Internal morphology
KW - Boric acid
U2 - 10.1080/00914037.2019.1581202
DO - 10.1080/00914037.2019.1581202
M3 - Journal article
VL - 69
SP - 525
EP - 534
JO - International Journal of Polymeric Materials and Polymeric Biomaterials
JF - International Journal of Polymeric Materials and Polymeric Biomaterials
SN - 0091-4037
IS - 8
ER -