We have over 12,000 students, from over 100 countries, within one of the safest campuses in the UK


93% of Lancaster students go into work or further study within six months of graduating

Home > Research > Publications & Outputs > Calcium based signalling in guard cells.
View graph of relations

« Back

Calcium based signalling in guard cells.

Research output: Contribution to journalJournal article


  • Carl K.-Y. Ng
  • Martin McAinsh
  • Julie E. Gray
  • Lee Hunt
  • Callum P. Leckie
  • Lewis Mills
  • Alistair M. Hetherington
Journal publication date07/2001
JournalNew Phytologist
Number of pages12
Original languageEnglish


Calcium is a ubiquitous intracellular signal responsible for controlling numerous cellular processes in both plants and animals. As an example, Ca2+ has been shown to be a second messenger in the signal transduction pathways by which stomatal guard cells respond to external stimuli. Regulated increases in the cytosolic concentration of free calcium ions ([Ca2+]cyt) in guard cells have been observed to be a common intermediate in many of the pathways leading to either opening or closing of the stomatal pore. This observation has prompted investigations into how specificity is encoded in the Ca2+ signal. It has been suggested that the key to generating stimulus-specific calcium signatures lies in the ability to access differentially the cellular machinery controlling calcium influx and release from intracellular stores. Several important components of the calcium-based signalling pathways have been identified in guard cells including cADPR, phospholipase C–InsP3, InsP6 and H2O2. These data suggest that the pathways for intracellular mobilization of Ca2+ are evolutionarily conserved between plants and animals.