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Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability

Research output: Contribution to journalJournal article

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Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. / Alhamoruni, A.; Wright, Karen; Larvin, M.; O'Sullivan, S. E.

In: British Journal of Pharmacology, Vol. 165, No. 8, 04.2012, p. 2598-610.

Research output: Contribution to journalJournal article

Harvard

Alhamoruni, A, Wright, K, Larvin, M & O'Sullivan, SE 2012, 'Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability', British Journal of Pharmacology, vol. 165, no. 8, pp. 2598-610. https://doi.org/10.1111/j.1476-5381.2011.01589.x

APA

Alhamoruni, A., Wright, K., Larvin, M., & O'Sullivan, S. E. (2012). Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. British Journal of Pharmacology, 165(8), 2598-610. https://doi.org/10.1111/j.1476-5381.2011.01589.x

Vancouver

Alhamoruni A, Wright K, Larvin M, O'Sullivan SE. Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. British Journal of Pharmacology. 2012 Apr;165(8):2598-610. https://doi.org/10.1111/j.1476-5381.2011.01589.x

Author

Alhamoruni, A. ; Wright, Karen ; Larvin, M. ; O'Sullivan, S. E. / Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. In: British Journal of Pharmacology. 2012 ; Vol. 165, No. 8. pp. 2598-610.

Bibtex

@article{c44b38eb0a724d999428f8d4eb9daa23,
title = "Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability",
abstract = "Activation of cannabinoid receptors decreases emesis, inflammation, gastric acid secretion and intestinal motility. The ability to modulate intestinal permeability in inflammation may be important in therapy aimed at maintaining epithelial barrier integrity. The aim of the present study was to determine whether cannabinoids modulate the increased permeability associated with inflammation in vitro.",
keywords = "intestinal permeability, inflammation, Caco-2 cells, cytokines, transepithelial electrical resistance (TEER), endocannabinoid , cannabinoid CB1 receptor;Δ9-tetrahydrocannabinol and cannabidiol",
author = "A. Alhamoruni and Karen Wright and M. Larvin and O'Sullivan, {S. E.}",
note = "{\textcopyright} 2011 The Authors. British Journal of Pharmacology {\textcopyright} 2011 The British Pharmacological Society.",
year = "2012",
month = apr,
doi = "10.1111/j.1476-5381.2011.01589.x",
language = "English",
volume = "165",
pages = "2598--610",
journal = "British Journal of Pharmacology",
issn = "0007-1188",
publisher = "Wiley-Blackwell",
number = "8",

}

RIS

TY - JOUR

T1 - Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability

AU - Alhamoruni, A.

AU - Wright, Karen

AU - Larvin, M.

AU - O'Sullivan, S. E.

N1 - © 2011 The Authors. British Journal of Pharmacology © 2011 The British Pharmacological Society.

PY - 2012/4

Y1 - 2012/4

N2 - Activation of cannabinoid receptors decreases emesis, inflammation, gastric acid secretion and intestinal motility. The ability to modulate intestinal permeability in inflammation may be important in therapy aimed at maintaining epithelial barrier integrity. The aim of the present study was to determine whether cannabinoids modulate the increased permeability associated with inflammation in vitro.

AB - Activation of cannabinoid receptors decreases emesis, inflammation, gastric acid secretion and intestinal motility. The ability to modulate intestinal permeability in inflammation may be important in therapy aimed at maintaining epithelial barrier integrity. The aim of the present study was to determine whether cannabinoids modulate the increased permeability associated with inflammation in vitro.

KW - intestinal permeability

KW - inflammation

KW - Caco-2 cells

KW - cytokines

KW - transepithelial electrical resistance (TEER)

KW - endocannabinoid

KW - cannabinoid CB1 receptor;Δ9-tetrahydrocannabinol and cannabidiol

UR - http://www.scopus.com/inward/record.url?scp=84859051261&partnerID=8YFLogxK

U2 - 10.1111/j.1476-5381.2011.01589.x

DO - 10.1111/j.1476-5381.2011.01589.x

M3 - Journal article

C2 - 21745190

VL - 165

SP - 2598

EP - 2610

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 0007-1188

IS - 8

ER -