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Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone. / Howlett, Patrick J.; Walder, Anna R.; Lisk, Durodami R. et al.
In: Emerging Infectious Diseases, Vol. 24, No. 8, 24.08.2018, p. 1412-1421.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Howlett, PJ, Walder, AR, Lisk, DR, Fitzgerald, F, Sevalie, S, Lado, M, N’Jai, A, Brown, CS, Sahr, F, Sesay, F, Read, JM, Steptoe, PJ, Beare, NAV, Dwivedi, R, Solbrig, M, Deen, GF, Solomon, T, Semple, MG & Scott, JT 2018, 'Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone', Emerging Infectious Diseases, vol. 24, no. 8, pp. 1412-1421. https://doi.org/10.3201/eid2408.171367

APA

Howlett, P. J., Walder, A. R., Lisk, D. R., Fitzgerald, F., Sevalie, S., Lado, M., N’Jai, A., Brown, C. S., Sahr, F., Sesay, F., Read, J. M., Steptoe, P. J., Beare, N. A. V., Dwivedi, R., Solbrig, M., Deen, G. F., Solomon, T., Semple, M. G., & Scott, J. T. (2018). Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone. Emerging Infectious Diseases, 24(8), 1412-1421. https://doi.org/10.3201/eid2408.171367

Vancouver

Howlett PJ, Walder AR, Lisk DR, Fitzgerald F, Sevalie S, Lado M et al. Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone. Emerging Infectious Diseases. 2018 Aug 24;24(8):1412-1421. doi: 10.3201/eid2408.171367

Author

Howlett, Patrick J. ; Walder, Anna R. ; Lisk, Durodami R. et al. / Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone. In: Emerging Infectious Diseases. 2018 ; Vol. 24, No. 8. pp. 1412-1421.

Bibtex

@article{46cee287032d4ea09385681097ca4f76,
title = "Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone",
abstract = "We describe a case series of 35 Ebola virus disease (EVD) survivors during the epidemic in West Africa who had neurologic and accompanying psychiatric sequelae. Survivors meeting neurologic criteria were invited from a cohort of 361 EVD survivors to attend a preliminary clinic. Those whose severe neurologic features were documented in the preliminary clinic were referred for specialist neurologic evaluation, ophthalmologic examination, and psychiatric assessment. Of 35 survivors with neurologic sequelae, 13 had migraine headache, 2 stroke, 2 peripheral sensory neuropathy, and 2 peripheral nerve lesions. Of brain computed tomography scans of 17 patients, 3 showed cerebral and/or cerebellar atrophy and 2 confirmed strokes. Sixteen patients required mental health follow-up; psychiatric disorders were diagnosed in 5. The 10 patients who experienced greatest disability had co-existing physical and mental health conditions. EVD survivors may have ongoing central and peripheral nervous system disorders, including previously unrecognized migraine headaches and stroke.",
author = "Howlett, {Patrick J.} and Walder, {Anna R.} and Lisk, {Durodami R.} and Felicity Fitzgerald and Stephen Sevalie and Marta Lado and Abdul N{\textquoteright}Jai and Brown, {Colin S.} and Foday Sahr and Foday Sesay and Read, {Jonathan M.} and Steptoe, {Paul J.} and Beare, {Nicholas A.V.} and Reena Dwivedi and Marylou Solbrig and Deen, {Gibrilla F.} and Tom Solomon and Semple, {Malcolm G.} and Scott, {Janet T.}",
year = "2018",
month = aug,
day = "24",
doi = "10.3201/eid2408.171367",
language = "English",
volume = "24",
pages = "1412--1421",
journal = "Emerging Infectious Diseases",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "8",

}

RIS

TY - JOUR

T1 - Case series of severe neurologic sequelae of ebola virus disease during epidemic, Sierra Leone

AU - Howlett, Patrick J.

AU - Walder, Anna R.

AU - Lisk, Durodami R.

AU - Fitzgerald, Felicity

AU - Sevalie, Stephen

AU - Lado, Marta

AU - N’Jai, Abdul

AU - Brown, Colin S.

AU - Sahr, Foday

AU - Sesay, Foday

AU - Read, Jonathan M.

AU - Steptoe, Paul J.

AU - Beare, Nicholas A.V.

AU - Dwivedi, Reena

AU - Solbrig, Marylou

AU - Deen, Gibrilla F.

AU - Solomon, Tom

AU - Semple, Malcolm G.

AU - Scott, Janet T.

PY - 2018/8/24

Y1 - 2018/8/24

N2 - We describe a case series of 35 Ebola virus disease (EVD) survivors during the epidemic in West Africa who had neurologic and accompanying psychiatric sequelae. Survivors meeting neurologic criteria were invited from a cohort of 361 EVD survivors to attend a preliminary clinic. Those whose severe neurologic features were documented in the preliminary clinic were referred for specialist neurologic evaluation, ophthalmologic examination, and psychiatric assessment. Of 35 survivors with neurologic sequelae, 13 had migraine headache, 2 stroke, 2 peripheral sensory neuropathy, and 2 peripheral nerve lesions. Of brain computed tomography scans of 17 patients, 3 showed cerebral and/or cerebellar atrophy and 2 confirmed strokes. Sixteen patients required mental health follow-up; psychiatric disorders were diagnosed in 5. The 10 patients who experienced greatest disability had co-existing physical and mental health conditions. EVD survivors may have ongoing central and peripheral nervous system disorders, including previously unrecognized migraine headaches and stroke.

AB - We describe a case series of 35 Ebola virus disease (EVD) survivors during the epidemic in West Africa who had neurologic and accompanying psychiatric sequelae. Survivors meeting neurologic criteria were invited from a cohort of 361 EVD survivors to attend a preliminary clinic. Those whose severe neurologic features were documented in the preliminary clinic were referred for specialist neurologic evaluation, ophthalmologic examination, and psychiatric assessment. Of 35 survivors with neurologic sequelae, 13 had migraine headache, 2 stroke, 2 peripheral sensory neuropathy, and 2 peripheral nerve lesions. Of brain computed tomography scans of 17 patients, 3 showed cerebral and/or cerebellar atrophy and 2 confirmed strokes. Sixteen patients required mental health follow-up; psychiatric disorders were diagnosed in 5. The 10 patients who experienced greatest disability had co-existing physical and mental health conditions. EVD survivors may have ongoing central and peripheral nervous system disorders, including previously unrecognized migraine headaches and stroke.

U2 - 10.3201/eid2408.171367

DO - 10.3201/eid2408.171367

M3 - Journal article

C2 - 30014839

AN - SCOPUS:85050385726

VL - 24

SP - 1412

EP - 1421

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 8

ER -