Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Cerebellar contributions to spatial memory
AU - Tomlinson, Simon P
AU - Davis, Nick J
AU - Morgan, Helen M
AU - Bracewell, R Martyn
N1 - Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
PY - 2014/8/22
Y1 - 2014/8/22
N2 - There is mounting evidence for a role for the cerebellum in working memory (WM). The majority of relevant studies has examined verbal WM and has suggested specialisation of the right cerebellar hemisphere for language processing. Our study used theta burst stimulation (TBS) to examine whether there is a converse cerebellar hemispheric specialisation for spatial WM. We conducted two experiments to examine spatial WM performance before and after TBS to mid-hemispheric and lateral locations in the posterior cerebellum. Participants were required to recall the order of presentation of targets on a screen or the targets' order of presentation and their locations. We observed impaired recollection of target order after TBS to the mid left cerebellar hemisphere and reduced response speed after TBS to the left lateral cerebellum. We suggest that these results give evidence of the contributions of the left cerebellar cortex to the encoding and retrieval of spatial information.
AB - There is mounting evidence for a role for the cerebellum in working memory (WM). The majority of relevant studies has examined verbal WM and has suggested specialisation of the right cerebellar hemisphere for language processing. Our study used theta burst stimulation (TBS) to examine whether there is a converse cerebellar hemispheric specialisation for spatial WM. We conducted two experiments to examine spatial WM performance before and after TBS to mid-hemispheric and lateral locations in the posterior cerebellum. Participants were required to recall the order of presentation of targets on a screen or the targets' order of presentation and their locations. We observed impaired recollection of target order after TBS to the mid left cerebellar hemisphere and reduced response speed after TBS to the left lateral cerebellum. We suggest that these results give evidence of the contributions of the left cerebellar cortex to the encoding and retrieval of spatial information.
KW - Adult
KW - Cerebellum
KW - Female
KW - Humans
KW - Male
KW - Memory, Short-Term
KW - Spatial Memory
KW - Transcranial Magnetic Stimulation
KW - Young Adult
KW - Journal Article
U2 - 10.1016/j.neulet.2014.06.057
DO - 10.1016/j.neulet.2014.06.057
M3 - Journal article
C2 - 25004407
VL - 578
SP - 182
EP - 186
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
ER -