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cGAS-independent STING activation in response to DNA damage

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cGAS-independent STING activation in response to DNA damage. / Unterholzner, Leonie; Dunphy, Gillian.

In: Molecular & Cellular Oncology, Vol. 6, No. 4, e1558682 , 19.04.2019.

Research output: Contribution to journalJournal article

Harvard

Unterholzner, L & Dunphy, G 2019, 'cGAS-independent STING activation in response to DNA damage', Molecular & Cellular Oncology, vol. 6, no. 4, e1558682 . https://doi.org/10.1080/23723556.2018.1558682

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Unterholzner, Leonie ; Dunphy, Gillian. / cGAS-independent STING activation in response to DNA damage. In: Molecular & Cellular Oncology. 2019 ; Vol. 6, No. 4.

Bibtex

@article{b2561a39bf68475988addf542d450840,
title = "cGAS-independent STING activation in response to DNA damage",
abstract = "Self-DNA has previously been thought to be protected from immune detection by compartmentalisation in the nucleus or mitochondria. Here, we describe the discovery of a signalling cascade that links the detection of DNA damage in the nucleus to the activation of the innate immune adaptor STING (STimulator of INterfern Genes).",
author = "Leonie Unterholzner and Gillian Dunphy",
year = "2019",
month = "4",
day = "19",
doi = "10.1080/23723556.2018.1558682",
language = "English",
volume = "6",
journal = "Molecular & Cellular Oncology",
issn = "2372-3556",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - cGAS-independent STING activation in response to DNA damage

AU - Unterholzner, Leonie

AU - Dunphy, Gillian

PY - 2019/4/19

Y1 - 2019/4/19

N2 - Self-DNA has previously been thought to be protected from immune detection by compartmentalisation in the nucleus or mitochondria. Here, we describe the discovery of a signalling cascade that links the detection of DNA damage in the nucleus to the activation of the innate immune adaptor STING (STimulator of INterfern Genes).

AB - Self-DNA has previously been thought to be protected from immune detection by compartmentalisation in the nucleus or mitochondria. Here, we describe the discovery of a signalling cascade that links the detection of DNA damage in the nucleus to the activation of the innate immune adaptor STING (STimulator of INterfern Genes).

U2 - 10.1080/23723556.2018.1558682

DO - 10.1080/23723556.2018.1558682

M3 - Journal article

VL - 6

JO - Molecular & Cellular Oncology

JF - Molecular & Cellular Oncology

SN - 2372-3556

IS - 4

M1 - e1558682

ER -