Although recent advancements in technology have led to major transformations in healthcare services, the use of tele-monitoring in patient care is yet an emerging occurrence. This study examines factors that affect the adoption of video based remote treatment of senior patients in a tele-glaucoma project in a large hospital in Greece. Several themes emerge from the study encapsulating technical, usability, process, institutional, ethics and privacy, clinicians’ behaviour and patients’ demography related factors. The findings of the study showed that while the benefits of tele-monitoring service adoption were of foremost importance for doctors, usability and connectivity for enabling remote services was critical for its success.