Comparative in vitro study of honey based and silver based wound preparations on cell viability

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Comparative in vitro study of honey based and silver based wound preparations on cell viability. / Tshukudu, Gloria M.; van der Walt, Marilize; Wessels, Quenton.
In: Burns, Vol. 36, No. 7, 11.2010, p. 1036-1041.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Tshukudu, GM, van der Walt, M & Wessels, Q 2010, 'Comparative in vitro study of honey based and silver based wound preparations on cell viability', Burns, vol. 36, no. 7, pp. 1036-1041. https://doi.org/10.1016/j.burns.2010.01.016

APA

Tshukudu, G. M., van der Walt, M., & Wessels, Q. (2010). Comparative in vitro study of honey based and silver based wound preparations on cell viability. Burns, 36(7), 1036-1041. https://doi.org/10.1016/j.burns.2010.01.016

Vancouver

Tshukudu GM, van der Walt M, Wessels Q. Comparative in vitro study of honey based and silver based wound preparations on cell viability. Burns. 2010 Nov;36(7):1036-1041. doi: 10.1016/j.burns.2010.01.016

Author

Tshukudu, Gloria M. ; van der Walt, Marilize ; Wessels, Quenton. / Comparative in vitro study of honey based and silver based wound preparations on cell viability. In: Burns. 2010 ; Vol. 36, No. 7. pp. 1036-1041.

Bibtex

@article{b15bfa6ecb224829989ac4535f0aa70c,

title = "Comparative in vitro study of honey based and silver based wound preparations on cell viability",

abstract = "Since the early 1980s a plethora of dressings has been developed to promote wound healing. The objective of this study was to compare the effects of silver based dressings and honey based dressings on cell viability.Materials and methodsIn this blinded study, keratinocyte cultures were exposed to prepared extracts of each of the following wound dressings for 40 h:•Silver based dressings: Acticoat, Actisorb, Askina, Atrauman-Ag and Contreet.•Honey based dressings: Melladerm gel, Melladerm mesh, Melladerm plus and Mellarsorb. Controls consisted of cells that were cultured in the same medium, and under the same conditions as those exposed to extracts.ResultsAll dressing extracts had an effect on cell viability. Changes in cell morphology from different wound dressing extracts were noted and compared with control groups after 24 h of incubation.ConclusionsIn the silver based extracts group, Atrauman-silver and Acticoat had the most viable cells. For the honey based group, the most viable cells were seen with Melladerm mesh and Mellasorb. There was no significant difference between the best performing silver and honey based wound preparations with regard to cell viability.",

keywords = "Comparative, In vitro , Silver based , Honey based , Cell viability",

author = "Tshukudu, {Gloria M.} and {van der Walt}, Marilize and Quenton Wessels",

year = "2010",

month = nov,

doi = "10.1016/j.burns.2010.01.016",

language = "English",

volume = "36",

pages = "1036--1041",

journal = "Burns",

issn = "0305-4179",

publisher = "Elsevier Limited",

number = "7",

}

RIS

TY - JOUR

T1 - Comparative in vitro study of honey based and silver based wound preparations on cell viability

AU - Tshukudu, Gloria M.

AU - van der Walt, Marilize

AU - Wessels, Quenton

PY - 2010/11

Y1 - 2010/11

N2 - Since the early 1980s a plethora of dressings has been developed to promote wound healing. The objective of this study was to compare the effects of silver based dressings and honey based dressings on cell viability.Materials and methodsIn this blinded study, keratinocyte cultures were exposed to prepared extracts of each of the following wound dressings for 40 h:•Silver based dressings: Acticoat, Actisorb, Askina, Atrauman-Ag and Contreet.•Honey based dressings: Melladerm gel, Melladerm mesh, Melladerm plus and Mellarsorb. Controls consisted of cells that were cultured in the same medium, and under the same conditions as those exposed to extracts.ResultsAll dressing extracts had an effect on cell viability. Changes in cell morphology from different wound dressing extracts were noted and compared with control groups after 24 h of incubation.ConclusionsIn the silver based extracts group, Atrauman-silver and Acticoat had the most viable cells. For the honey based group, the most viable cells were seen with Melladerm mesh and Mellasorb. There was no significant difference between the best performing silver and honey based wound preparations with regard to cell viability.

AB - Since the early 1980s a plethora of dressings has been developed to promote wound healing. The objective of this study was to compare the effects of silver based dressings and honey based dressings on cell viability.Materials and methodsIn this blinded study, keratinocyte cultures were exposed to prepared extracts of each of the following wound dressings for 40 h:•Silver based dressings: Acticoat, Actisorb, Askina, Atrauman-Ag and Contreet.•Honey based dressings: Melladerm gel, Melladerm mesh, Melladerm plus and Mellarsorb. Controls consisted of cells that were cultured in the same medium, and under the same conditions as those exposed to extracts.ResultsAll dressing extracts had an effect on cell viability. Changes in cell morphology from different wound dressing extracts were noted and compared with control groups after 24 h of incubation.ConclusionsIn the silver based extracts group, Atrauman-silver and Acticoat had the most viable cells. For the honey based group, the most viable cells were seen with Melladerm mesh and Mellasorb. There was no significant difference between the best performing silver and honey based wound preparations with regard to cell viability.

KW - Comparative

KW - In vitro

KW - Silver based

KW - Honey based

KW - Cell viability

U2 - 10.1016/j.burns.2010.01.016

DO - 10.1016/j.burns.2010.01.016

M3 - Journal article

VL - 36

SP - 1036

EP - 1041

JO - Burns

JF - Burns

SN - 0305-4179

IS - 7

ER -

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