Two different design methods for customized cranioplasty prostheses are presented in this paper. The first approach is designing the digital model of the cranial implants in a haptic environment, utilizing a combination of a PHANToM haptic device and a freeform software called Claytools. The other method makes use of a software solution provided by Materialise Inc. known as 3-matic. Next, the skull models and the designed implants are fabricated via stereolitography (SLA). Finally, the implants’ fit over the skull models are evaluated to determine the most accurate method.