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Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published

Standard

Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science. / Skeldon, K. D.; Gibson, G. M.; Wyse, C. A. et al.
In: Applied Optics, Vol. 44, No. 22, 08.2005, p. 4712-4721.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Skeldon, KD, Gibson, GM, Wyse, CA, McMillan, LC, Monk, SD, Longbottom, C & Padgett, MJ 2005, 'Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science.', Applied Optics, vol. 44, no. 22, pp. 4712-4721. <http://www.ncbi.nlm.nih.gov/pubmed/16075884>

APA

Skeldon, K. D., Gibson, G. M., Wyse, C. A., McMillan, L. C., Monk, S. D., Longbottom, C., & Padgett, M. J. (2005). Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science. Applied Optics, 44(22), 4712-4721. http://www.ncbi.nlm.nih.gov/pubmed/16075884

Vancouver

Skeldon KD, Gibson GM, Wyse CA, McMillan LC, Monk SD, Longbottom C et al. Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science. Applied Optics. 2005 Aug;44(22):4712-4721.

Author

Skeldon, K. D. ; Gibson, G. M. ; Wyse, C. A. et al. / Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science. In: Applied Optics. 2005 ; Vol. 44, No. 22. pp. 4712-4721.

Bibtex

@article{172c1f85c7124a6bbfb04d328b8d7818,
title = "Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science.",
abstract = "We describe a high-resolution real-time spectroscopy system targeted to ethane gas with sensitivity >= 70 ppt and response time from >= 0.7 s. The measurement technique is based on a mid-IR lead-salt laser passing through a Herriott cell through which a gas sample flows. We compare wavelength scanning and locked configurations and discuss their relative merits. The technology has been motivated by clinical breath testing applications, ethane being widely regarded as the most important breath biomarker for cell damage via free-radical-mediated oxidative attack. We discuss preliminary human and animal studies in which ultrasensitive real-time ethane detection offers new diagnostic and monitoring potential. (c) 2005 Optical Society of America.",
author = "Skeldon, {K. D.} and Gibson, {G. M.} and Wyse, {C. A.} and McMillan, {L. C.} and Monk, {S. D.} and C. Longbottom and Padgett, {M. J.}",
year = "2005",
month = aug,
language = "English",
volume = "44",
pages = "4712--4721",
journal = "Applied Optics",
issn = "2155-3165",
publisher = "The Optical Society",
number = "22",

}

RIS

TY - JOUR

T1 - Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science.

AU - Skeldon, K. D.

AU - Gibson, G. M.

AU - Wyse, C. A.

AU - McMillan, L. C.

AU - Monk, S. D.

AU - Longbottom, C.

AU - Padgett, M. J.

PY - 2005/8

Y1 - 2005/8

N2 - We describe a high-resolution real-time spectroscopy system targeted to ethane gas with sensitivity >= 70 ppt and response time from >= 0.7 s. The measurement technique is based on a mid-IR lead-salt laser passing through a Herriott cell through which a gas sample flows. We compare wavelength scanning and locked configurations and discuss their relative merits. The technology has been motivated by clinical breath testing applications, ethane being widely regarded as the most important breath biomarker for cell damage via free-radical-mediated oxidative attack. We discuss preliminary human and animal studies in which ultrasensitive real-time ethane detection offers new diagnostic and monitoring potential. (c) 2005 Optical Society of America.

AB - We describe a high-resolution real-time spectroscopy system targeted to ethane gas with sensitivity >= 70 ppt and response time from >= 0.7 s. The measurement technique is based on a mid-IR lead-salt laser passing through a Herriott cell through which a gas sample flows. We compare wavelength scanning and locked configurations and discuss their relative merits. The technology has been motivated by clinical breath testing applications, ethane being widely regarded as the most important breath biomarker for cell damage via free-radical-mediated oxidative attack. We discuss preliminary human and animal studies in which ultrasensitive real-time ethane detection offers new diagnostic and monitoring potential. (c) 2005 Optical Society of America.

M3 - Journal article

VL - 44

SP - 4712

EP - 4721

JO - Applied Optics

JF - Applied Optics

SN - 2155-3165

IS - 22

ER -